78606-80-1
78606-80-1
Chemical Structure
BML-111
- CAS 番号: 78606-80-1
- Formula:C8H16O5
- Molecular Weight:192.21
IUPAC Name: methyl (5S,6R)-5,6,7-trihydroxyheptanoate
InChIKey: RNMFWAFZUNVQOR-NKWVEPMBSA-N
SMILES: O=C(OC)CCC[C@H](O)[C@H](O)CO
Biological Activity: BML-111, a lipoxin A4 analog, is a lipoxin A4 receptor agonist. BML-111 represses the activity of angiotensin converting enzyme (ACE) and increases the activity of angiotensinconverting enzyme 2 (ACE2). BML-111 has antiangiogenic, antitumor and anti-inflammatory properties[1][2].
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BML-111 | 98.87% | BML-111, a lipoxin A4 analog, is a lipoxin A4 receptor agonist. BML-111 represses the activity of angiotensin converting enzyme (ACE) and increases the activity of angiotensinconverting enzyme 2 (ACE2). BML-111 has antiangiogenic, antitumor and anti-inflammatory properties. | ||||||||||||||||||||
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BML-111 (Standard) | ≥98% | BML-111 (Standard) is the analytical standard of BML-111 (HY-100450). This product is intended for research and analytical applications. BML-111, a lipoxin A4 analog, is a lipoxin A4 receptor agonist. BML-111 represses the activity of angiotensin converting enzyme (ACE) and increases the activity of angiotensinconverting enzyme 2 (ACE2). BML-111 has antiangiogenic, antitumor and anti-inflammatory properties. | ||||||||||||||||||||
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References
- [1]. Ying Chen, et al. Lipoxin A4 and Its Analogue Suppress the Tumor Growth of Transplanted H22 in Mice: The Role of Antiangiogenesis. Mol Cancer Ther. 2010 Aug;9(8):2164-74. [Content Brief]
- [2]. Qiong-Feng Chen, et al. BML-111, a Lipoxin Receptor Agonist, Protects Against Acute Injury via Regulating the Renin Angiotensin-Aldosterone System. Prostaglandins Other Lipid Mediat. 2019 Feb;140:9-17. [Content Brief]
