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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
77 Results for "
ANGPTL
" in MedChemExpress (MCE) Product Catalog:
Products (77)
77 Results for "ANGPTL" in MCE Product Catalog:
2
2 Cited Publications
Cat. No.: HY-P7507
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ANGPTL4; Peroxisome Proliferator-Activated Receptor (PPAR) Gamma Induced Angiopoietin-Related Protein; Angiopoietin Like 4; Hepatic Angiopoietin-Related Protein; HFARP; PPARG Angiopoietin Related Protein; PGAR; Fasting-Induced Adipose Factor; ARP4; Angiopoietin-Like Protein 4; Hepatic Fibrinogen/Angiopoietin-Related Protein; Angiopoietin-Like 4; Angiopoietin-Related Protein 4; UNQ171; Pp1158; TGQTL; FIAF; HARP; NL2
Species:
Human
Source:
HEK293
1
Target:
Research Areas:
1
1 Cited Publications
Cat. No.: HY-P7508
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ANGPTL4; Peroxisome Proliferator-Activated Receptor (PPAR) Gamma Induced Angiopoietin-Related Protein; Angiopoietin Like 4; Hepatic Angiopoietin-Related Protein; HFARP; PPARG Angiopoietin Related Protein; PGAR; Fasting-Induced Adipose Factor; ARP4; Angiop
Species:
Mouse
Source:
HEK293
Research Areas:
JTE-907 is a selective and orally active cannabinoid CB2 receptor inverse agonist and exerts anti-inflammatory effects. JTE-907 upregulates IL-6, MCP-1, IL-1β, VEGF, ANGPTL4, and TRPV1 in mature adipocytes. JTE-907 downregulates CB1, MCP-1, and IL-1β in preadipocytes. JTE-907 inhibits ear swelling in mice. JTE-907 reverses the protective effects of CB2 agonists and Anandamide (HY-10863) against cytokine-evoked colonic mucosal damage. JTE-907 can be used for the research of allergic dermatitis, obesity, and colitis .
Cat. No.: HY-163794
CAS No.: 2135765-21-6
Research Areas:
DC371739 is a potent and orally activity PCSK9 inhibitor. DC371739 decreases the mRNA expression of PCSK9 and ANGPTL3. DC371739 decreases the protein expression of PCSK9 and increases the protein expression of LDLR. DC371739 has the potential for the research of hyperlipidemia .
Cat. No.: HY-P990335
Target:
Research Areas:
Cat. No.: HY-177671
CAS No.: 2232918-66-8
Synonyms: ARO-ANG3
Target:
Research Areas:
Zodasiran is a siRNA targeted to ANGPTL3 in the liver.
Synonyms: IONIS ANGPT-L3Rx sodium; ISIS 703802 sodium
Target:
Research Areas:
Vupanorsen (sodium) is an N-acetyl galactosamine-conjugated antisense oligonucleotide that inhibits Angiopoietin-like 3 (ANGPTL3) protein synthesis. Vupanorsen (sodium) lowers triglycerides and atherogenic lipoproteins.
Cat. No.: HY-RS00693
Target:
Research Areas:
ANGPTL4 Human Pre-designed siRNA Set A contains three designed siRNAs for ANGPTL4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-159709
CAS No.: 2765519-47-7
Target:
Research Areas:
VL-422 is an ionizable cationic lipid. VL-422 delivers CRISPR complementary single-guide RNA (sgRNA) and Cas9 mRNA to enable in vitro and in vivo gene editing. LNPs containing VL-422 loaded with Cas9 mRNA and sgRNA targeting the ANGPTL3 gene induce the deletion of premature stop codons within the ANGPTL3 gene in the liver of cynomolgus monkeys. Loss-of-function of ANGPTL3 leads to decreased levels of LDL, HDL and cholesterol in plasma. The VL-422 delivery system can be used for the research of gene editing strategies targeting lipid metabolism diseases .
Cat. No.: HY-RS16575
Target:
Research Areas:
Angptl4 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Angptl4 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-177666
CAS No.: 2718150-11-7
Synonyms: LY3561774
Target:
Research Areas:
Solbinsiran is a siRNA targeted to hepatic ANGPTL3.
Cat. No.: HY-177666A
CAS No.: 2707429-60-3
Synonyms: LY3561774 sodium
Target:
Research Areas:
Solbinsiran sodium is a siRNA targeted to hepatic ANGPTL3.
Cat. No.: HY-177671A
CAS No.: 2232918-74-8
Synonyms: ARO-ANG3 sodium
Target:
Research Areas:
Zodasiran sodium is a siRNA targeted to ANGPTL3 in the liver.
Cat. No.: HY-153497
CAS No.: 2097587-62-5
Synonyms: IONIS ANGPT-L3Rx; ISIS 703802
Target:
Research Areas:
Vupanorsen is an N-acetyl galactosamine-conjugated antisense oligonucleotide that inhibits Angiopoietin-like 3 (ANGPTL3) protein synthesis. Vupanorsen lowers triglycerides and atherogenic lipoproteins.
Cat. No.: HY-P990336
Target:
Research Areas:
Cat. No.: HY-RS00690
Target:
Research Areas:
ANGPTL1 Human Pre-designed siRNA Set A contains three designed siRNAs for ANGPTL1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS00692
Target:
Research Areas:
ANGPTL3 Human Pre-designed siRNA Set A contains three designed siRNAs for ANGPTL3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS00694
Target:
Research Areas:
ANGPTL5 Human Pre-designed siRNA Set A contains three designed siRNAs for ANGPTL5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS00695
Target:
Research Areas:
ANGPTL6 Human Pre-designed siRNA Set A contains three designed siRNAs for ANGPTL6 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
