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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
ATP-competitive catalytic site
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "ATP-competitive catalytic site" in MCE Product Catalog:
16
16 Cited Publications
Target:
Research Areas:
PHA-665752 is a selective, ATP-competitive, and active-site inhibitor of the catalytic activity of c-Met kinase (Ki=4 nM; IC50=9 nM). PHA-665752 exhibits >50-fold selectivity for c-Met compared with a panel of diverse tyrosine and serine-threonine kinases. PHA-665752 induces apoptosis and cell cycle arrest, and exhibits cytoreductive antitumor activity .
Cat. No.: HY-D1493
CAS No.: 220518-50-3
Cat. No.: HY-11107R
CAS No.: 477575-56-7
Research Areas:
PHA-665752 (Standard) is the analytical standard of PHA-665752 (HY-11107). This product is intended for research and analytical applications. PHA-665752 is a selective, ATP-competitive, and active-site inhibitor of the catalytic activity of c-Met Kinase (Ki=4 nM; IC50=9 nM). PHA-665752 exhibits >50-fold selectivity for c-Met compared with a panel of diverse tyrosine and serine-threonine Kinases. PHA-665752 induces apoptosis and cell cycle arrest, and exhibits cytoreductive antitumor activity .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
