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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
13 Results for "
Alkylating metabolite
" in MedChemExpress (MCE) Product Catalog:
Products (13)
13 Results for "Alkylating metabolite" in MCE Product Catalog:
2
2 Cited Publications
Cat. No.: HY-114577
CAS No.: 1070409-31-2
Synonyms: Isophosphoramide mustard tromethamine; IPM tromethamine; ZIO-201 tromethamine
Target:
Research Areas:
Palifosfamide (tromethamine) is a synthetic alkylating agent with potential antineoplastic activity. As the stabilized active metabolite of ifosfamide, palifosfamide (tromethamine) irreversibly alkylates and crosslinks DNA through GC base pairs. This leads to an inhibition of DNA replication and ultimately cell death. Compared to ifosfamide, palifosfamide (tromethamine) is less toxic.
1
1 Cited Publications
Synonyms: Resacetophenone; 1-(2,4-Dihydroxyphenyl)ethanone
Target:
Target:
Research Areas:
MTIC, the active metabolite of Temozolomide (TMZ), is a DNA alkylating agent. MTIC has antitumor activity
.
Cat. No.: HY-W007337
CAS No.: 627-18-9
Cat. No.: HY-W587524
CAS No.: 22788-18-7
Target:
Research Areas:
Carboxyphosphamide is an inactive metabolite of the alkylating agent Cyclophosphamide (HY-17420) .
Cat. No.: HY-136327
CAS No.: 10477-72-2
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Research Areas:
Phenylacetic acid mustard is the major metabolite of the cancer chemotherapeutic agent Chlorambucil (HY-13593). Chlorambucil is an alkylating agent with antitumor activity .
Cat. No.: HY-13533
CAS No.: 176046-79-0
Synonyms: NSC 682691; 4-Demethylpenclomedine
Target:
Research Areas:
DMPEN (NSC 682691) (4-Demethylpenclomedine) is an alkylating metabolite of Penclomedine (HY-106401). DMPEN has an antitumor activity. DMPEN does not induce Purkinje cells loss with no significant neurocerebellar toxicity in rat cerebellum models. DMPEN can be used for cancers like breast and brain cancer research .
Cat. No.: HY-W740674
CAS No.: 27046-19-1
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Research Areas:
4-Ketocyclophosphamide is an inactive metabolite of the alkylating agent Cyclophosphamide (HY-17420).
Category:
Cat. No.: HY-119696R
CAS No.: 3413-72-7
Target:
Research Areas:
MTIC (Standard) is the analytical standard of MTIC. This product is intended for research and analytical applications. MTIC, the active metabolite of Temozolomide (TMZ), is a DNA alkylating agent. MTIC has antitumor activity
[1][2][3][4].
Cat. No.: HY-119696S1
Cat. No.: HY-W1057999
CAS No.: 104149-14-6
Target:
Research Areas:
Bromofosfamide is a prodrug-type alkylating agent and also an analog of Ifosfamide (HY-17419). Bromofosfamide exhibits potent in vivo anti-tumor activity against lymphoid leukemia and can be used for the research of lymphoid leukemia .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
