89-84-9
Chemical Structure
2',4'-Dihydroxyacetophenone
Synonym(s): Resacetophenone; 1-(2,4-Dihydroxyphenyl)ethanone
- CAS No.: 89-84-9
- Formula:C8H8O3
- Molecular Weight:152.15
IUPAC Name: 1-(2,4-dihydroxyphenyl)ethan-1-one
InChIKey: SULYEHHGGXARJS-UHFFFAOYSA-N
SMILES: CC(C1=CC=C(O)C=C1O)=O
Biological Activity: 2',4'-Dihydroxyacetophenone (Resacetophenone) is acetophenone carrying hydroxy substituents at positions 2' and 4'. 2',4'-Dihydroxyacetophenone involves in a practical CsHCO3-mediated alkylation that efficiently provide 4-alkylated products with excellent regioselectivity, good isolated yields and a broad substrate scope. 2',4'-Dihydroxyacetophenone is a plant metabolite[1][2][3].
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2',4'-Dihydroxyacetophenone | 99.94% | 2',4'-Dihydroxyacetophenone (Resacetophenone) is acetophenone carrying hydroxy substituents at positions 2' and 4'. 2',4'-Dihydroxyacetophenone involves in a practical CsHCO3-mediated alkylation that efficiently provide 4-alkylated products with excellent regioselectivity, good isolated yields and a broad substrate scope. 2',4'-Dihydroxyacetophenone is a plant metabolite. | ||||||||||||||||||||
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2',4'-Dihydroxyacetophenone (Standard) | ≥98% | 2',4'-Dihydroxyacetophenone (Resacetophenone) is acetophenone carrying hydroxy substituents at positions 2' and 4'. 2',4'-Dihydroxyacetophenone involves in a practical CsHCO3-mediated alkylation that efficiently provide 4-alkylated products with excellent regioselectivity, good isolated yields and a broad substrate scope. 2',4'-Dihydroxyacetophenone is a plant metabolite. | ||||||||||||||||||||
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References
- [1]. Li XJ, et al. Bioactive metabolites from biotransformation of paeonol by the white-rot basidiomycete Coriolus versicolor. Nat Prod Commun. 2011 Aug;6(8):1129-30. [Content Brief]
- [2]. Baughman RG, et al. 2,4-Dinitrophenylhydrazones of 2,4-dihydroxybenzaldehyde, 2,4-dihydroxyacetophenone and 2,4-dihydroxybenzophenone. Acta Crystallogr C. 2004 Feb;60(Pt 2):o103-6. [Content Brief]
- [3]. Frank A, et al. Regioselective alkylation of 2,4-dihydroxybenzyaldehydes and 2,4-dihydroxyacetophenones. Tetrahedron Lett. 2022 Apr 13;95:153755. [Content Brief]
