30 Results for "

Amino-PEG3-C2-Azido

" in MedChemExpress (MCE) Product Catalog:
Products (30)

30 Results for "Amino-PEG3-C2-Azido" in MCE Product Catalog:

Referencia número: HY-W021401
No. CAS: 134179-38-7
Target:  

PROTAC Linkers

Áreas de investigación:  

Cancer

Amino-PEG3-C2-Azido is a PEG-based PROTAC linker can be used in the synthesis of the PARP1 degrader iRucaparib-TP3 (HY-130645) . Amino-PEG3-C2-Azido is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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4
4 Cited Publications
Referencia número: HY-P2336A
Target:  

Melanocortin Receptor

Áreas de investigación:  

Cancer

CCZ01048 TFA, a α-MSH analogue, exhibits high binding affinity to melanocortin 1 receptor (MC1R) with a Ki of 0.31 nM. CCZ01048 TFA shows rapid internalization into B16F10 melanoma cells and high in vivo stability. CCZ01048 TFA is a promising candidate for PET imaging of malignant melanoma .
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1
1 Cited Publications
Referencia número: HY-105055
No. CAS: 77327-05-0
Pureza:  99.95%
Didemnin B is a depsipeptide extracted from the marine tunicate Trididemnin cyanophorum. Didemnin B can be used for the research of cancer .
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Referencia número: HY-P4070
No. CAS: 1188379-43-2
Target:  

Insulin Receptor

Áreas de investigación:  

Metabolic Disease

Insulin icodec is an Insulin (HY-P0035) analog that strongly but reversibly binds to albumin. Insulin icodec has long plasma half-life. Insulin icodec modulates insulin receptor activity, controls blood glucose levels, reduces HbA1c levels, and binds reversibly to human serum albumin. Insulin icodec can be used for the research of type 2 diabetes mellitus .
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Referencia número: HY-172320
No. CAS: 2919596-13-5
Target:  

PD-1/PD-L1

Áreas de investigación:  

Cancer

BMS-986238 is an orally active macrocyclic peptide PD-L1 inhibitor. BMS-986238 can be used in the research of tumors such as solid tumors and lymphomas .
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Referencia número: HY-P5362
NODAGA-LM3 is a ligand that can cross the blood-brain barrier and targets somatostatin receptor SSTR2 with high affinity (IC50 = 1.3 nM). NODAGA-LM3 does not trigger the internalization of SSTR2 and can inhibit agonist-induced internalization processes. NODAGA-LM3 shows low uptake in normal tissues such as the liver and spleen, but high uptake in the lungs and blood pool. 68Ga-labeled NODAGA-LM3 can serve as a PET imaging agent for well-differentiated neuroendocrine tumors, and is applied in studies related to small cell lung cancer and well-differentiated neuroendocrine tumors .
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Referencia número: HY-P5112A
Synonyms: Azido-PEG3-FLAG TFA
Áreas de investigación:  

Others

Azido-PEG3-DYKDDDDK (azide-PEG3-FLAG) TFA is a multifunctional fusion tag for the purification of recombinant proteins. Azido-PEG3-DYKDDDDK TFA is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups .
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Referencia número: HY-P10341
No. CAS: 1345835-12-2
Target:  

GCGR

Áreas de investigación:  

Metabolic Disease

ZP3022 is a dual agonist of glucagon-like peptide-1 (GLP-1) and gastrin that has the ability to sustainably improve glycemic control. Additionally, ZP3022 can effectively increase β-cell mass, promote β-cell proliferation, and enhance the function of pancreatic islets. ZP3022 can be used in anti-diabetic research .
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Referencia número: HY-P5112
No. CAS: 2243206-95-1
Synonyms: Azido-PEG3-FLAG
Áreas de investigación:  

Others

Azido-PEG3-DYKDDDDK (azide-PEG3-FLAG) is a multifunctional fusion tag for the purification of recombinant proteins. Azido-PEG3-DYKDDDDK is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups .
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Referencia número: HY-169089
Target:  

Drug Derivative

Áreas de investigación:  

Cancer

RP-182-PEG3-K palmitic acid-NH2 (Compound 1a) is a fatty acid derivative of the immunomodulatory peptide RP-182. RP-182-PEG3-K palmitic acid-NH2 inhibits CD206 high M2-like macrophage (IC50 of 3.2 μM) and induces phagocytosis. RP-182-PEG3-K palmitic acid-NH2 exhibits antitumor efficacy in mouse B16 melanoma allografts .
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Referencia número: HY-176240
No. CAS: 3085085-29-3
Target:  

AUTACs Autophagy

Áreas de investigación:  

Cancer

FBnG-amino-PEG3-C2-azido is a tag-linker conjugate that incorporates a degradation tag FBnG (HY-W073762) and a glycol linker (Amino-PEG3-C2-Azido) (HY-W021401). FBnG-amino-PEG3-C2-azido can be used for synthesis of GPX4-AUTAC (HY-176220) .
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Referencia número: HY-P11270
No. CAS: 2843676-09-3
Synonyms: BGM0504; BG128
Áreas de investigación:  

Metabolic Disease

Relsipatide (BG128) is a dual gastric inhibitory polypeptide (GIP) and glucagon-like peptide 1 (GLP-1) receptor agonist. Enicepatide can be studied in antidiabetic research .
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Referencia número: HY-169089A
Target:  

Drug Derivative

Áreas de investigación:  

Cancer

RP-182-PEG3-K(palmitic acid)-NH2 (Compound 1a) TFA is a fatty acid derivative of the immunomodulatory peptide RP-182. RP-182-PEG3-K(palmitic acid)-NH2 TFA inhibits CD206 high M2-like macrophage (IC50 of 3.2 μM) and induces phagocytosis. RP-182-PEG3-K(palmitic acid)-NH2 TFA exhibits antitumor efficacy in mouse B16 melanoma allografts .
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Referencia número: HY-P5025
No. CAS: 1392269-21-4
Synonyms: Azido-c(RGDyK)
Target:  

Drug Intermediate

Áreas de investigación:  

Others

Cyclo(Arg-Gly-Asp-D-Tyr-ε-azido-Nle) (Azido-c(RGDyK)) is a polypeptide composed of arginine, glycine, aspartic acid, and tyrosine that can be used for Synthesis of [ 18F]FPyKYNE-c(RGDyK) .
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Referencia número: HY-P11004
Target:  

Bacterial Antibiotic

Áreas de investigación:  

Infection

A3-APO is an antimicrobial peptide. A3-APO has a significant antimicrobial activity by a dual mode of action with both membrane disintegration and intracellular target inhibition. A3-APO can deactivate bacterial toxins and increase the expression of anti-inflammatory cytokines (such as IL-4 and IL-10), without antimicrobial resistance. A3-APO accelerates burn wounds healing in mice infection model of Acinetobacter baumannii and Staphylococcus aureus .
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Referencia número: HY-P10319
Target:  

PKA

Áreas de investigación:  

Cardiovascular Disease Cancer

RI-STAD-2 is a high-affinity interfering peptide that regulates the subunit RI of protein kinase A (PKA). RI-STAD-2 interferes with the binding of AKAPs and PKA-RI by simulating the interaction between AKAPs' α-helix domain and PKA-RI's dimerization/anchoration (D/D) domain, thereby affecting PKA activity and intracellular localization. RI-STAD-2 can be used to study the role of AKAPs interaction with PKA-RI in pathological processes such as cardiovascular disease and cancer .
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Referencia número: HY-P10472
No. CAS: 134457-28-6
Target:  

GnRH Receptor

Áreas de investigación:  

Endocrinology

Azaline B is an antagonist for gonadotropin-releasing hormone (GnRH) with IC50 of 1.37 nM, Azaline B can be used in research of sex hormone-related pathological states, ovulation induction and male contraception .
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Referencia número: HY-P4757
No. CAS: 108081-77-2
Target:  

Parasite

Áreas de investigación:  

Others

N1-Glutathionyl-spermidine disulfide is a substrate of trypanothione reductase .
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Referencia número: HY-P11243
Target:  

Ephrin Receptor

Áreas de investigación:  

Neurological Disease

EphA4 agonist compound 23 is a novel EphA4 agonist peptide mimic. EphA4 agonist compound 23 exhibits high affinity, high selectivity, and significant receptor activation ability. EphA4 agonist compound 23 is commonly used in the study of neurodegenerative diseases .
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Referencia número: HY-P2434
No. CAS: 846569-60-6
Target:  

Somatostatin Receptor

Áreas de investigación:  

Neurological Disease Metabolic Disease Cancer

AP102 is a dual SSTR2/SSTR5-specific somatostatin analog (SSA). AP102 is a disulfide-bridged octapeptide SSA containing synthetic iodinated amino acids. AP102 binds with subnanomolar affinity to SSTR2 and SSTR5 (IC50: 0.63 and 0.65 nM, respectively). AP102 does not bind to SSTR1 or SSTR3. AP102 can be used for acromegaly and neuroendocrine tumors research .
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