134179-38-7

Amino-PEG3-C2-Azido Chemical Structure
134179-38-7

Chemical Structure

Amino-PEG3-C2-Azido

  • CAS. Nr.: 134179-38-7
  • Formula:C8H18N4O3
  • Molecular Weight:218.25

IUPAC Name: 2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)ethan-1-amine

InChIKey: FPVCVHVTMPCZTH-UHFFFAOYSA-N

SMILES: [N-]=[N+]=NCCOCCOCCOCCN

Biological Activity: Amino-PEG3-C2-Azido is a PEG-based PROTAC linker can be used in the synthesis of the PARP1 degrader iRucaparib-TP3 (HY-130645)[1]. Amino-PEG3-C2-Azido is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Art. -Nr. Produktname Reinheit Beschreibung Pricing
HY-W021401 		Amino-PEG3-C2-Azido 98.96% Amino-PEG3-C2-Azido is a PEG-based PROTAC linker can be used in the synthesis of the PARP1 degrader iRucaparib-TP3 (HY-130645). Amino-PEG3-C2-Azido is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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