134179-38-7
Chemical Structure
Amino-PEG3-C2-Azido
- CAS No.: 134179-38-7
- Formula:C8H18N4O3
- Molecular Weight:218.25
IUPAC Name: 2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)ethan-1-amine
InChIKey: FPVCVHVTMPCZTH-UHFFFAOYSA-N
SMILES: [N-]=[N+]=NCCOCCOCCOCCN
Biological Activity: Amino-PEG3-C2-Azido is a PEG-based PROTAC linker can be used in the synthesis of the PARP1 degrader iRucaparib-TP3 (HY-130645)[1]. Amino-PEG3-C2-Azido is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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Amino-PEG3-C2-Azido | 98.96% | Amino-PEG3-C2-Azido is a PEG-based PROTAC linker can be used in the synthesis of the PARP1 degrader iRucaparib-TP3 (HY-130645). Amino-PEG3-C2-Azido is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | ||||||||||||||||||||
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Keywords
