5 Results for "

Anti-IL-5 Antibody

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "Anti-IL-5 Antibody" in MCE Product Catalog:

Cat. No.: HY-P990452

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Anti-IL-5 Antibody is a CHO-expressed humanized antibody that targets IL-5. The Anti-IL-5 Antibody is composed of huIgG4 heavy chains and huκ light chains, with a predicted molecular weight (MW) of 150 kDa. The isotype control for Anti-IL-5 Antibody can be referenced as Human IgG4 kappa, Isotype Control (HY-P99003).
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1 Cited Publications
Cat. No.: HY-P9923A
CAS No.: 1044511-01-4
Synonyms: MEDI-563 (Anti-IL5RA); BIW-8405 (Anti-IL5RA); KHK4563 (Anti-IL5RA)
Benralizumab (anti-IL5RA) (MEDI-563 (anti-IL5RA); BIW-8405 (anti-IL5RA)) is an interleukin-5 receptor α (IL-5Rα)-directed cytolytic monoclonal antibody that induces direct, rapid and nearly complete depletion of eosinophils via enhanced antibody-dependent cell-mediated cytotoxicity. Benralizumab can be used for severe eosinophilic asthma study .
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Cat. No.: HY-P9945A
CAS No.: 196078-29-2

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Mepolizumab (anti-IL5) is a humanized monoclonal antibody that binds to and neutralizes interleukin-5 (IL-5), the major cytokine involved in eosinophil proliferation, activation, and survival. Mepolizumab can be used for the research of eosinophilic granulomatosis with polyangiitis (EGPA) and severe eosinophilic asthma .
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Cat. No.: HY-P99850
CAS No.: 2243274-14-6
Synonyms: GSK-3511294

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Depemokimab (GSK-3511294) is a long-acting anti-IL-5 monoclonal antibody. Depemokimab can be used for research of asthma .
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Cat. No.: HY-P991599

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

SHR-1703 is a long-acting humanized anti-IL-5 IgG1 monoclonal antibody. SHR-1703 can selectively recognize and bind to IL-5, blocking the binding of IL-5 to the α chain of the receptor on the surface of eosinophils, thereby inhibiting the proliferation, activation, and migration of eosinophils, and ultimately reducing eosinophil-mediated inflammation and damage. SHR-1703 can be used in the research of eosinophil-related diseases, such as eosinophilic asthma. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001) .
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