Search Result

Results for "

Avenanthramide L

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (3) Biochemical Assay Reagents (1) Collagen (1) CXCR (2) DNA/RNA Synthesis (3) Drug Derivative (1) Endogenous Metabolite (1) Fungal (1) Insulin Receptor (1) Interleukin Related (1) Isotope-Labeled Compounds (1) Melanocortin Receptor (1) Neuropeptide Y Receptor (2) NF-κB (1) Parasite (1) Reactive Oxygen Species (ROS) (3) Reference Standards (1) TGF-beta/Smad (1) Trk Receptor (1)
By Research Areas:	Cancer (6) Endocrinology (1) Infection (1) Inflammation/Immunology (5) Metabolic Disease (2) Neurological Disease (4)

Inhibitors & Agonists

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P4070

Insulin icodec	Insulin Receptor	Metabolic Disease
Insulin icodec is an Insulin (HY-P0035) analog that strongly but reversibly binds to albumin. Insulin icodec has long plasma half-life. Insulin icodec modulates insulin receptor activity, controls blood glucose levels, reduces HbA_1c levels, and binds reversibly to human serum albumin. Insulin icodec can be used for the research of type 2 diabetes mellitus .

HY-118693

Avenanthramide D Dianthramide P	Drug Derivative	Inflammation/Immunology
Avenanthramide D is a phenolic acids found in the Avena sativa L.. Avenanthramide D is promising for research of inflammation .

HY-P1103

CTCE-9908 1 Publications Verification	CXCR	Cancer
CTCE-9908 is a potent and selective CXCR4 antagonist. CTCE-9908 induces mitotic catastrophe, cytotoxicity and inhibits migration in CXCR4-expressing ovarian cancer cells .

HY-124344

Avenanthramide C	Interleukin Related	Neurological Disease
Avenanthramide C is an orally active avenanthramide that can be isolated from oat seeds. Avenanthramide C decreases the protein expression of cleaved caspase-3 and increases the expression of p-GSK3β(Ser9) and IL-10 levels. Avenanthramide C has the potential for the research of Alzheimer’s disease .

HY-114977

Avenanthramide A	DNA/RNA Synthesis Apoptosis Reactive Oxygen Species (ROS)	Inflammation/Immunology Cancer
Avenanthramide A is an orally active phytoalexin that targets the RNA helicase DDX3 with a K_D of 8.8 μM. Avenanthramide A induces mitochondrial swelling and increased ROS production, and triggers apoptosis in CRC cells. Avenanthramide A inhibits smooth muscle cell proliferation and enhances nitric oxide production. Avenanthramide A can be used in research on colorectal cancer and atherosclerosis .

HY-114977R

Avenanthramide A (Standard)	Reference Standards Apoptosis DNA/RNA Synthesis Reactive Oxygen Species (ROS)	Inflammation/Immunology Cancer
Avenanthramide A (Standard) is the analytical standard of Avenanthramide A. This product is intended for research and analytical applications. Avenanthramide A is an orally active phytoalexin that targets the RNA helicase DDX3 with a K_D of 8.8 μM. Avenanthramide A induces mitochondrial swelling and increased ROS production, and triggers apoptosis in CRC cells. Avenanthramide A inhibits smooth muscle cell proliferation and enhances nitric oxide production. Avenanthramide A can be used in research on colorectal cancer and atherosclerosis .

HY-P1103A

CTCE-9908 TFA	CXCR	Cancer
CTCE-9908 TFA is a potent and selective CXCR4 antagonist. CTCE-9908 TFA induces mitotic catastrophe, cytotoxicity and inhibits migration in CXCR4-expressing ovarian cancer cells .

HY-P4757

N1-Glutathionyl-spermidine disulfide	Parasite	Others
N1-Glutathionyl-spermidine disulfide is a substrate of trypanothione reductase .

HY-P11293

DOTA-GGNle-CycMSHhex	Melanocortin Receptor	Cancer
DOTA-GGNle-CycMSHhex is a melanocortin-1 receptor (MC1R)-targeting peptide that can be radionuclide-labeled for melanoma imaging .

HY-P1321

GR231118 1229U91; GW1229	Neuropeptide Y Receptor	Neurological Disease
GR231118, an analogue of the C-terminus of neuropeptide Y, is a potent , competitive and relative seletive antagonist at human neuropeptide Y Y receptor with a pK_i of 10.4. GR231118 a potent agonist at the human neuropeptide Y Y4 receptor (pEC₅₀=8.6; pK_i=9.6) and a weak agonist at the human and rat neuropeptide YY2 and Y5 receptors. GR231118 also has high affinity for the mouse neuropeptide Y Y6 receptor (pK_i= 8.8) .

HY-114977S

Avenanthramide A-d4	Isotope-Labeled Compounds Apoptosis DNA/RNA Synthesis Reactive Oxygen Species (ROS)	Inflammation/Immunology Cancer
Avenanthramide A-d₄ is the deuterium labeled Avenanthramide A (HY-114977). Avenanthramide A is an orally active phytoalexin that targets the RNA helicase DDX3 with a K_D of 8.8 μM. Avenanthramide A induces mitochondrial swelling and increased ROS production, and triggers apoptosis in CRC cells. Avenanthramide A inhibits smooth muscle cell proliferation and enhances nitric oxide production. Avenanthramide A can be used in research on colorectal cancer and atherosclerosis .

HY-N18069

Avenanthramide L	Fungal Endogenous Metabolite	Infection
Avenanthramide L is a phytoalexin that can inhibit the spore germination of Puccinia coronata f. sp. avenae. Avenanthramide L is found in the leaves of inoculated oats, but not in the leaves of healthy oat seedlings, and at a concentration of 200-300 μg/mL. Avenanthramide L inhibits fungal spore germination by up to 50%. Avenanthramide L is absent from the leaves of healthy oat seedlings. Avenanthramide L can be used for the research of oat crown rust .

HY-138284

Avenanthramide-C methyl ester	NF-κB	Inflammation/Immunology
Avenanthramide-C methyl ester is an anti-inflammatory agent and NF-κB inhibitor that inhibits the secretion of pro-inflammatory factors. Avenanthramide-C methyl ester inhibits NF-κB activation by inhibiting IKK and IκB phosphorylation and inhibiting proteasome activity .

HY-P1321A

GR231118 TFA 1229U91 TFA; GW1229 TFA	Neuropeptide Y Receptor	Neurological Disease
GR231118 TFA, an analogue of the C-terminus of neuropeptide Y, is a potent , competitive and relative seletive antagonist at human neuropeptide YY receptor with a pK_i of 10.4. GR231118 a potent agonist at the human neuropeptide YY4 receptor (pEC₅₀=8.6; pK_i=9.6) and a weak agonist at the human and rat neuropeptide Y Y2 and Y5 receptors. GR231118 also has high affinity for the mouse neuropeptide YY6 receptor (pK_i= 8.8) .

HY-N17673

Avenanthramide 1c	Biochemical Assay Reagents	Others
Avenanthramide 1c is a free radical scavenger and antioxidant. Avenanthramide 1c scavenges DPPH free radicals. Avenanthramide 1c inhibits azo-initiated linoleic acid peroxidation. Avenanthramide 1c exerts antioxidant effects. Avenanthramide 1c exhibits an antagonistic interaction with Avenanthramide 2f in the DPPH free radical scavenging system .

HY-126734

Avenanthramide E	TGF-beta/Smad Collagen	Metabolic Disease Endocrinology
Avenanthramide E (Compound 5) is a collagen synthesis inhibitor. Avenanthramide E inhibits TGF-β-stimulated Collagen synthesis. Avenanthramide E can be used for the research of diabetic nephropathy .

HY-P11480

TrkA/NGF-IN-1	Trk Receptor	Neurological Disease
TrkA/NGF-IN-1 (Peptide 19) is an inhibitor of protein-protein interactions between TrkA and NGF (IC₅₀: 21 nM for human TrkA in PathHunter assay). TrkA/NGF-IN-1 shows an analgesic effect in a rat incisional pain model .

Cat. No.	Product Name	Target	Research Area

HY-P4070

Insulin icodec	Insulin Receptor	Metabolic Disease
Insulin icodec is an Insulin (HY-P0035) analog that strongly but reversibly binds to albumin. Insulin icodec has long plasma half-life. Insulin icodec modulates insulin receptor activity, controls blood glucose levels, reduces HbA_1c levels, and binds reversibly to human serum albumin. Insulin icodec can be used for the research of type 2 diabetes mellitus .

HY-P1103

CTCE-9908 1 Publications Verification	CXCR	Cancer
CTCE-9908 is a potent and selective CXCR4 antagonist. CTCE-9908 induces mitotic catastrophe, cytotoxicity and inhibits migration in CXCR4-expressing ovarian cancer cells .

HY-P1103A

CTCE-9908 TFA	CXCR	Cancer
CTCE-9908 TFA is a potent and selective CXCR4 antagonist. CTCE-9908 TFA induces mitotic catastrophe, cytotoxicity and inhibits migration in CXCR4-expressing ovarian cancer cells .

HY-P4757

N1-Glutathionyl-spermidine disulfide	Parasite	Others
N1-Glutathionyl-spermidine disulfide is a substrate of trypanothione reductase .

HY-P11293

DOTA-GGNle-CycMSHhex	Melanocortin Receptor	Cancer
DOTA-GGNle-CycMSHhex is a melanocortin-1 receptor (MC1R)-targeting peptide that can be radionuclide-labeled for melanoma imaging .

HY-P1321

GR231118 1229U91; GW1229	Neuropeptide Y Receptor	Neurological Disease
GR231118, an analogue of the C-terminus of neuropeptide Y, is a potent , competitive and relative seletive antagonist at human neuropeptide Y Y receptor with a pK_i of 10.4. GR231118 a potent agonist at the human neuropeptide Y Y4 receptor (pEC₅₀=8.6; pK_i=9.6) and a weak agonist at the human and rat neuropeptide YY2 and Y5 receptors. GR231118 also has high affinity for the mouse neuropeptide Y Y6 receptor (pK_i= 8.8) .

HY-P1321A

GR231118 TFA 1229U91 TFA; GW1229 TFA	Neuropeptide Y Receptor	Neurological Disease
GR231118 TFA, an analogue of the C-terminus of neuropeptide Y, is a potent , competitive and relative seletive antagonist at human neuropeptide YY receptor with a pK_i of 10.4. GR231118 a potent agonist at the human neuropeptide YY4 receptor (pEC₅₀=8.6; pK_i=9.6) and a weak agonist at the human and rat neuropeptide Y Y2 and Y5 receptors. GR231118 also has high affinity for the mouse neuropeptide YY6 receptor (pK_i= 8.8) .

HY-P11480

TrkA/NGF-IN-1	Trk Receptor	Neurological Disease
TrkA/NGF-IN-1 (Peptide 19) is an inhibitor of protein-protein interactions between TrkA and NGF (IC₅₀: 21 nM for human TrkA in PathHunter assay). TrkA/NGF-IN-1 shows an analgesic effect in a rat incisional pain model .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-118693

Avenanthramide D Dianthramide P	Simple Phenylpropanols Phenylpropanoids Endogenous metabolite Source Classification	Drug Derivative
Avenanthramide D is a phenolic acids found in the Avena sativa L.. Avenanthramide D is promising for research of inflammation .

HY-124344

Avenanthramide C	Simple Phenylpropanols Avena sativa Linn. Gramineae Phenylpropanoids Plants Source Classification	Interleukin Related
Avenanthramide C is an orally active avenanthramide that can be isolated from oat seeds. Avenanthramide C decreases the protein expression of cleaved caspase-3 and increases the expression of p-GSK3β(Ser9) and IL-10 levels. Avenanthramide C has the potential for the research of Alzheimer’s disease .

HY-114977

Avenanthramide A	Structural Classification Avena sativa Linn. Gramineae Phenols Polyphenols Plants Source Classification	DNA/RNA Synthesis Apoptosis Reactive Oxygen Species (ROS)
Avenanthramide A is an orally active phytoalexin that targets the RNA helicase DDX3 with a K_D of 8.8 μM. Avenanthramide A induces mitochondrial swelling and increased ROS production, and triggers apoptosis in CRC cells. Avenanthramide A inhibits smooth muscle cell proliferation and enhances nitric oxide production. Avenanthramide A can be used in research on colorectal cancer and atherosclerosis .

HY-114977R

Avenanthramide A (Standard)	Structural Classification Avena sativa Linn. Gramineae Phenols Polyphenols Plants Source Classification	Reference Standards Apoptosis DNA/RNA Synthesis Reactive Oxygen Species (ROS)
Avenanthramide A (Standard) is the analytical standard of Avenanthramide A. This product is intended for research and analytical applications. Avenanthramide A is an orally active phytoalexin that targets the RNA helicase DDX3 with a K_D of 8.8 μM. Avenanthramide A induces mitochondrial swelling and increased ROS production, and triggers apoptosis in CRC cells. Avenanthramide A inhibits smooth muscle cell proliferation and enhances nitric oxide production. Avenanthramide A can be used in research on colorectal cancer and atherosclerosis .

HY-N18069

Avenanthramide L	Structural Classification Alkaloids Microorganisms Other Alkaloids Source Classification	Fungal Endogenous Metabolite
Avenanthramide L is a phytoalexin that can inhibit the spore germination of Puccinia coronata f. sp. avenae. Avenanthramide L is found in the leaves of inoculated oats, but not in the leaves of healthy oat seedlings, and at a concentration of 200-300 μg/mL. Avenanthramide L inhibits fungal spore germination by up to 50%. Avenanthramide L is absent from the leaves of healthy oat seedlings. Avenanthramide L can be used for the research of oat crown rust .

HY-N17673

Avenanthramide 1c	Structural Classification Avena sativa Linn. Gramineae Phenols Polyphenols Plants Source Classification	Biochemical Assay Reagents
Avenanthramide 1c is a free radical scavenger and antioxidant. Avenanthramide 1c scavenges DPPH free radicals. Avenanthramide 1c inhibits azo-initiated linoleic acid peroxidation. Avenanthramide 1c exerts antioxidant effects. Avenanthramide 1c exhibits an antagonistic interaction with Avenanthramide 2f in the DPPH free radical scavenging system .

HY-126734

Avenanthramide E	Structural Classification Monophenols Avena sativa Linn. Gramineae Phenols Plants Source Classification	TGF-beta/Smad Collagen
Avenanthramide E (Compound 5) is a collagen synthesis inhibitor. Avenanthramide E inhibits TGF-β-stimulated Collagen synthesis. Avenanthramide E can be used for the research of diabetic nephropathy .

Cat. No.	Product Name	Chemical Structure

HY-114977S

Avenanthramide A-d4
Avenanthramide A-d₄ is the deuterium labeled Avenanthramide A (HY-114977). Avenanthramide A is an orally active phytoalexin that targets the RNA helicase DDX3 with a K_D of 8.8 μM. Avenanthramide A induces mitochondrial swelling and increased ROS production, and triggers apoptosis in CRC cells. Avenanthramide A inhibits smooth muscle cell proliferation and enhances nitric oxide production. Avenanthramide A can be used in research on colorectal cancer and atherosclerosis .

Avenanthramide A-d4

Avenanthramide A-d₄ is the deuterium labeled Avenanthramide A (HY-114977). Avenanthramide A is an orally active phytoalexin that targets the RNA helicase DDX3 with a K_D of 8.8 μM. Avenanthramide A induces mitochondrial swelling and increased ROS production, and triggers apoptosis in CRC cells. Avenanthramide A inhibits smooth muscle cell proliferation and enhances nitric oxide production. Avenanthramide A can be used in research on colorectal cancer and atherosclerosis .

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

Avenanthramide L

Inhibitors & Agonists

Peptides

NaturalProducts

Isotope-Labeled Compounds

Natural
Products