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Cat. No.: HY-126734

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Avenanthramide E

Avenanthramide E is a collagen synthesis inhibitor. Avenanthramide E inhibits TGF-β-stimulated Collagen synthesis. Avenanthramide E can be used for the research of diabetic nephropathy.

For research use only. We do not sell to patients.

CAS No.: 93755-77-2
Formula: C₁₇H₁₅NO₅
Molecular Weight:313.30

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Avenanthramide E Chemical Structure

CAS No.: 93755-77-2

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
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Bioz

Biological Activity

Description

Avenanthramide E is a collagen synthesis inhibitor. Avenanthramide E inhibits TGF-β-stimulated Collagen synthesis. Avenanthramide E can be used for the research of diabetic nephropathy^[1].

All TGF-beta/Smad Isoforms :

Smad1
Smad3

In Vitro

Avenanthramide E (Compound 5) (100 μM) inhibits TGF-β-stimulated collagen synthesis in cultured renal mesangial cells by 50% at a concentration of 100 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 93755-77-2
Molecular Weight 313.30
Formula C₁₇H₁₅NO₅
SMILES

O=C(O)C1=CC=CC=C1NC(/C=C/C2=CC=C(O)C(OC)=C2)=O
Structure Classification
- Phenols
- Monophenols
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Zammit SC, et al. Evaluation and optimization of antifibrotic activity of cinnamoyl anthranilates. Bioorg Med Chem Lett. 2009;19(24):7003-7006. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
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- In Vitro
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Avenanthramide E

All TGF-beta/Smad Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Avenanthramide E Related Classifications

HY-126734 Related Classifications