Avenanthramide 1c
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Avenanthramide 1c is a free radical scavenger and antioxidant. Avenanthramide 1c scavenges DPPH free radicals. Avenanthramide 1c inhibits azo-initiated linoleic acid peroxidation. Avenanthramide 1c exerts antioxidant effects. Avenanthramide 1c exhibits an antagonistic interaction with Avenanthramide 2f in the DPPH free radical scavenging system.
For research use only. We do not sell to patients.
- Purity: 98.43%
- CAS No.: 116764-16-0
- Formula: C16H13NO5
- Molecular Weight:299.28
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Storage:
Store at room temperature, keep dry and cool.
In solvent -80°C, 1 year , -20°C, 6 months
Biological Activity
Avenanthramide 1c (0.50 mM) exhibits potent DPPH free radical scavenging activity in hydrophilic systems, with a ΔA value of 31 at 2 minutes[1].
Avenanthramide 1c potently inhibits azo-initiated linoleic acid peroxidation in lipophilic systems, with a production slope of conjugated diene hydroperoxides of 1.0 μM/min within the first 30 minutes[1].
Avenanthramide 1c (40-90 μM; 20 min) exhibits a significant antagonistic effect against Avenanthramide 2f in the DPPH free radical scavenging system (p = 0.02)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 116764-16-0
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Appearance Solid
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Molecular Weight 299.28
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Formula C16H13NO5
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Color White to off-white
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SMILES
OC(C1=C(C=CC=C1)NC(/C=C/C2=CC(O)=C(C=C2)O)=O)=O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature, keep dry and cool
In solvent -80°C 1 year -20°C 6 months
Solvent & Solubility
DMSO : 100 mg/mL (334.14 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Bratt K, et al. Avenanthramides in oats (Avena sativa L.) and structure-antioxidant activity relationships. J Agric Food Chem. 2003;51(3):594-600. [Content Brief]
[2]. Sumayya PC, Babu GM, Muraleedharan K. Quantum chemical investigation of the antiradical property of avenanthramides, oat phenolics. Heliyon. 2021;7(2):e06125. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.3414 mL | 16.7068 mL | 33.4135 mL | 83.5338 mL |
| 5 mM | 0.6683 mL | 3.3414 mL | 6.6827 mL | 16.7068 mL | |
| 10 mM | 0.3341 mL | 1.6707 mL | 3.3414 mL | 8.3534 mL | |
| 15 mM | 0.2228 mL | 1.1138 mL | 2.2276 mL | 5.5689 mL | |
| 20 mM | 0.1671 mL | 0.8353 mL | 1.6707 mL | 4.1767 mL | |
| 25 mM | 0.1337 mL | 0.6683 mL | 1.3365 mL | 3.3414 mL | |
| 30 mM | 0.1114 mL | 0.5569 mL | 1.1138 mL | 2.7845 mL | |
| 40 mM | 0.0835 mL | 0.4177 mL | 0.8353 mL | 2.0883 mL | |
| 50 mM | 0.0668 mL | 0.3341 mL | 0.6683 mL | 1.6707 mL | |
| 60 mM | 0.0557 mL | 0.2784 mL | 0.5569 mL | 1.3922 mL | |
| 80 mM | 0.0418 mL | 0.2088 mL | 0.4177 mL | 1.0442 mL | |
| 100 mM | 0.0334 mL | 0.1671 mL | 0.3341 mL | 0.8353 mL |