39 Results for "

B-cell maturation antigen

" in MedChemExpress (MCE) Product Catalog:
Products (39)

39 Results for "B-cell maturation antigen" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-P9980
CAS No.: 2061894-48-0
Synonyms: GSK2857914

Research Areas:  

Cancer

Belantamab (GSK2857916) is a humanized IgG1 anti-BCMA/TNFRSF17 monoclonal antibody. Belantamab is linked to MMAF (HY-15579) through a non-cleavable ADC linker to synthesize the antibody-active molecule conjugate (ADC) Belantamab mafodotin (HY-P3239). After binding to BCMA on the surface of tumor cells, Belantamab mafodotin enters the cell through receptor-mediated endocytosis. After entering the cell, Belantamab mafodotin releases MMAF, blocks cell division by inhibiting tubulin polymerization, arrests the cell cycle and induces cell apoptosis. Belantamab can be used for the study of multiple myeloma, especially relapsed/refractory multiple myeloma .
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1
1 Cited Publications
Cat. No.: HY-P3239
CAS No.: 2050232-20-5
Synonyms: GSK2857916; Belantamab mafodotin-blm
Research Areas:  

Cancer

Belantamab mafodotin (GSK2857916) is composed of humanized and focused monoclonal antibody against B cell maturation antigen (BCMA) and McMMAF. The antibody portion is Belantamab (HY-P9980), and the drug-linker conjugate for ADC is McMMAF (HY-15578). Belantamab mafodotin has anti-myeloma activity .
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1
1 Cited Publications
Cat. No.: HY-P99814
CAS No.: 2250292-39-6
Synonyms: AMG-701

Target:  

CD3

Research Areas:  

Inflammation/Immunology Cancer

Pavurutamab (AMG-701) is a bispecific T cell engager molecule that anti-CD3 and anti-B cell maturation antigens (BCMA). Pavurutamab has an extended half-life based on Pacanalotamab (HY-P99798). The Fc of Pavurutamab is coupled to molecules to improve pharmacokinetic parameters. Pavurutamab has potential applications in immune regulation and multiple myeloma (MM) .
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Cat. No.: HY-P99798
CAS No.: 2251756-52-0
Synonyms: AMG 420; BI-836909

Target:  

CD3

Research Areas:  

Cancer

Pacanalotamab (AMG 420; BI-836909) is a bispecific T-cell engager (BiTE) targeting to BCMA and CD3E. BCMA refers to B cell maturation antigen, as Pacanalotamab redirecting T cells to BCMA expressing cells on the cell surface. Pacanalotamab conducts T-cell redirected lysis of human multiple myeloma (MM) cell lines .
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Cat. No.: HY-P9989
CAS No.: 2408319-25-3
Synonyms: REGN5458

Target:  

CD3 TNF Receptor

Research Areas:  

Cancer

Linvoseltamab (REGN5458) is a bispecific T-cell engager (BiTE) antibody that specifically binds to B cell maturation antigen (BCMA) and CD3 of T cells, thereby directing T cells to multiple myeloma (MM) cells expressing BCMA and activating T cells to kill tumor cells. Linvoseltamab can be used in research of relapsed/refractory multiple myeloma (RRMM) .
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Cat. No.: HY-P991490

Target:  

CD38 CD3 TNF Receptor

Research Areas:  

Cancer

ISB2001 is a trispecific antibody targeting CD38, CD3 and BCMA. ISB2001 effectively counteracts tumor immune escape mechanisms caused by antigen downregulation, antigen loss, soluble factor competition and other factors. ISB2001 is applicable to relevant research on multiple myeloma and relapsed/refractory multiple myeloma .
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Cat. No.: HY-P990980
CAS No.: 2919209-65-5
Synonyms: CND-106; EMB-06

Target:  

CD3

Research Areas:  

Inflammation/Immunology Cancer

Cizutamig (CND-106) is a bispecific T-cell engager targeting BCMA and CD3. Cizutamig exhibits immunostimulatory and anti-tumor activities. Cizutamig can be used in research related to relapsed or refractory multiple myeloma and systemic lupus erythematosus .
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Cat. No.: HY-P990785
CAS No.: 2490552-52-6
Synonyms: ABBV-383; TNB 383B

Target:  

CD3

Etentamig is a BCMA × CD3 bispecific T-cell engager (BiTE) that can inhibit the activity of B-cell maturation antigen (BCMA) and activate the T-cell surface glycoprotein CD3 complex. Etentamig can be used for research in multiple myeloma, immunoglobulin light chain amyloidosis, and cardiovascular diseases .
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Cat. No.: HY-P1700
CAS No.: 2293841-58-2
Target:  

TNF Receptor

Research Areas:  

Cancer

BCMA72-80 is a HLA-A2-specific B-cell maturation antigen (BCMA) peptide, with great affinity to HLA-A2, used in the research of multiple myeloma or other B-cell maturation antigen expressing tumors .
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Cat. No.: HY-P990939
CAS No.: 2851863-52-8
Synonyms: HPN 217
Target:  

CD3

Research Areas:  

Cancer

Podentamig (HPN 217) is a trispecific construct with three binding domains, including an anti-CD3 domain for T cell activation, an anti-BCMA domain for binding to plasma cells, and an anti-albumin domain for half-life extension. Podentamig is applicable to research related to relapsed/refractory multiple myeloma .
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Cat. No.: HY-P75591
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF17; TNFRSF13A; Prev. BCMA; Tumor Necrosis Factor Receptor Superfamily, Member 17; BCM; B cell maturation antigen; Tumor Necrosis Factor Receptor Superfamily Member 17; B-cell maturation Factor; B-cell maturation Protein; CD269 antigen; TNF Receptor
Species:  
Rat
Source:  
HEK293
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Cat. No.: HY-P72850
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF17; TNFRSF13A; Prev. BCMA; Tumor Necrosis Factor Receptor Superfamily, Member 17; BCM; B cell maturation antigen; Tumor Necrosis Factor Receptor Superfamily Member 17; B-cell maturation Factor; B-cell maturation Protein; CD269 antigen; TNF Receptor
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P76166
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF17; TNFRSF13A; Prev. BCMA; Tumor Necrosis Factor Receptor Superfamily, Member 17; BCM; B cell maturation antigen; Tumor Necrosis Factor Receptor Superfamily Member 17; B-cell maturation Factor; B-cell maturation Protein; CD269 antigen; TNF Receptor
Species:  
Rhesus Macaque
Source:  
HEK293
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Cat. No.: HY-P72849
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF17; TNFRSF13A; Prev. BCMA; Tumor Necrosis Factor Receptor Superfamily, Member 17; BCM; B cell maturation antigen; Tumor Necrosis Factor Receptor Superfamily Member 17; B-cell maturation Factor; B-cell maturation Protein; CD269 antigen; TNF Receptor
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P76167
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF17; TNFRSF13A; Prev. BCMA; Tumor Necrosis Factor Receptor Superfamily, Member 17; BCM; B cell maturation antigen; Tumor Necrosis Factor Receptor Superfamily Member 17; B-cell maturation Factor; B-cell maturation Protein; CD269 antigen; TNF Receptor
Species:  
Rhesus Macaque
Source:  
HEK293
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Cat. No.: HY-P72847
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF17; TNFRSF13A; Prev. BCMA; Tumor Necrosis Factor Receptor Superfamily, Member 17; BCM; B cell maturation antigen; Tumor Necrosis Factor Receptor Superfamily Member 17; B-cell maturation Factor; B-cell maturation Protein; CD269 antigen; TNF Receptor Superfamily Member 17; CD269
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P7132
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF17; TNFRSF13A; Prev. BCMA; Tumor Necrosis Factor Receptor Superfamily, Member 17; BCM; B cell maturation antigen; Tumor Necrosis Factor Receptor Superfamily Member 17; B-cell maturation Factor; B-cell maturation Protein; CD269 antigen; TNF Receptor
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P7654
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF17; TNFRSF13A; Prev. BCMA; Tumor Necrosis Factor Receptor Superfamily, Member 17; BCM; B cell maturation antigen; Tumor Necrosis Factor Receptor Superfamily Member 17; B-cell maturation Factor; B-cell maturation Protein; CD269 antigen; TNF Receptor
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P7656
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF17; TNFRSF13A; Prev. BCMA; Tumor Necrosis Factor Receptor Superfamily, Member 17; BCM; B cell maturation antigen; Tumor Necrosis Factor Receptor Superfamily Member 17; B-cell maturation Factor; B-cell maturation Protein; CD269 antigen; TNF Receptor
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P70778
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF17; TNFRSF13A; Prev. BCMA; Tumor Necrosis Factor Receptor Superfamily, Member 17; BCM; B cell maturation antigen; Tumor Necrosis Factor Receptor Superfamily Member 17; B-cell maturation Factor; B-cell maturation Protein; CD269 antigen; TNF Receptor
Species:  
Cynomolgus
Source:  
HEK293
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