1 Result for "

BI 02982816

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "BI 02982816" in MCE Product Catalog:

Cat. No.: HY-170499
CAS No.: 3100913-05-8
Synonyms: BI02982816
Target:  

mGluR

Research Areas:  

Neurological Disease

VU6024578 (BI02982816) is a selective, orally active positive allosteric modulator (PAM) for metabotropic glutamate receptor (mGluR1), that activates human mGluR1 and rat mGluR1 with EC50 of 54 nM and 46 nM. VU6024578 exhibits antipsychotic activity in rats amphetamine-induced hyperactivity models and MK-801 (HY-15084B)-induced novel object recognition (NOR) models. VU6024578 is blood brain barrier penetrable .
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