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Results for "

Bodipy probe

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (2) Bcl-2 Family (1) Btk (2) Caspase (1) Deubiquitinase (1) Fluorescent Dye (47) Ligands for E3 Ligase (1) MOFs (1) Reactive Oxygen Species (ROS) (1) Reference Standards (1)
By Research Areas:	Cancer (7) Inflammation/Immunology (2) Metabolic Disease (5) Neurological Disease (1)

Inhibitors & Agonists

Fluorescent Dyes

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-110210

BODIPY-FL NHS ester Bodipy FL,SE	Fluorescent Dye	Others
BODIPY FL NHS ester (BODIPY FL, SE) is a cell membranes-penatrable amine-reactive fluorescent probe. The maximum excitation/emission wavelength of the BODIPY-FL NHS ester are 502/511 nm, respectively. BODIPY-FL NHS ester has high stability and is insensitive to the polarity, pH and type of solvent, and can maintain stable fluorescence properties under different environmental conditions. BODIPY-FL NHS ester can be used for the synthesis of protease substrates, live cell imaging, protein labeling and immunoassay .

HY-43520

BODIPY-FL	Fluorescent Dye	Others
BODIPY-FL is a green fluorescent dye that can be used to label probes or primers. BODIPY-FL fluorescence can be quenched after interacting with uniquely positioned guanine, making it useful for quantifying specific DNA or RNA molecules. The maximum absorption wavelength of BODIPY-FL is 505 nm, and the maximum emission wavelength is 513 nm .

HY-D1297

ER-Tracker Green Maximum Cited Publications 6 Publications Verification	Fluorescent Dye	Others
ER-Tracker dye is a derivative of BODIPY series dyes coupled with Glibenclamide (HY-15206), highly selective binding to the endoplasmic reticulum, non-toxic to cells at low concentrations, this type of dye is an environmentally sensitive probe, and formaldehyde treatment can still retain part of the fluorescence, with high fluorescence life, good extinction coefficient and other characteristics. Glibenclamide is an atp-dependent K ⁺ channel blocker (Kir6, KATP) and CFTR Cl-channel blocker that binds in the endoplasmic reticulum. ER-Tracker is not suitable for staining cells after fixation .

HY-125623

MitoPerOx 3 Publications Verification	Fluorescent Dye	Others
MitoPerOx is a mitochondrial-targeted, lipid peroxidation-indicating fluorescent probe with BODIPY581/591 fluorophores. The triphenylphosphine cation (TPP+) of MitoPerOx can be selectively enriched in mitochondria (depending on membrane potential) and can be used to detect lipid peroxidation in the inner mitochondrial membrane. Under the action of lipid peroxides, the BODIPY581/591 fluorophores of MitoPerOx shift their emission wavelength from 590 nm (reduced state) to 520 nm (oxidized state), and ratiometric detection can be performed at an excitation wavelength of 488 nm. MitoPerOx can specifically monitor the peroxidation of mitochondrial phospholipids (especially cardiolipin) and is used in the study of oxidative stress-related diseases (such as aging, neurodegenerative diseases, and mitochondrial dysfunction)[1][2].

HY-D1431

ER-Tracker Red 4 Publications Verification	Fluorescent Dye	Cancer
ER-Tracker dye is a derivative of BODIPY series dyes coupled with Glibenclamide (HY-15206), highly selective binding to the endoplasmic reticulum, non-toxic to cells at low concentrations, this type of dye is an environmentally sensitive probe, and formaldehyde treatment can still retain part of the fluorescence, with high fluorescence life, good extinction coefficient and other characteristics. Glibenclamide is an atp-dependent K ⁺ channel blocker (Kir6, KATP) and CFTR Cl-channel blocker that binds in the endoplasmic reticulum. ER-Tracker is not suitable for staining cells after fixation. Ex/Em=587/615 nm .

HY-D1612

BODIPY FL C5-Ceramide	Fluorescent Dye	Others
The Golgi apparatus is composed of flattened vesicles superimposed on each other by unit membranes. The flattened vesicles are round with expanded and perforated edges. The Golgi fluorescent probe is a BODIPY-labeled ceramide derivative, the synthesis of which occurs in the endoplasmic reticulum and can then be transported to the Golgi via ceramide transport protein (CERT) or vesicular translocation, allowing specific labeling of the dye . BODIPY Fl C5-Ceramide is a Golgi-specific green fluorescent dye, which can visualise individual cells . Ex/Em= 505 nm/512 nm.

HY-N0729F

BODIPY-Linoleic acid	Fluorescent Dye	Metabolic Disease
BODIPY-Linoleic acid is a conjugate of the BODIPY fluorophore and Linoleic acid (HY-N0729) (C18:2) and is a lipid metabolism probe.

HY-D1429

ER-Tracker Blue-White DPX	Fluorescent Dye	Others
ER-Tracker dye is a derivative of BODIPY series dyes coupled with Glibenclamide (HY-15206), highly selective binding to the endoplasmic reticulum, non-toxic to cells at low concentrations, this type of dye is an environmentally sensitive probe, and formaldehyde treatment can still retain part of the fluorescence, with high fluorescence life, good extinction coefficient and other characteristics. Glibenclamide is an atp-dependent K ⁺ channel blocker (Kir6, KATP) and CFTR Cl-channel blocker that binds in the endoplasmic reticulum. ER-Tracker is not suitable for staining fixed cells. Staining followed by fixation is possible, but cells fixed with aldehydes will only retain partial fluorescence (Ex/Em = 374/ 430-640 nm) .

HY-115691

STY-BODIPY Styrene-Bodipy; Styrene-Conjugated Bodipy	Fluorescent Dye	Others
STY-BODIPY (Styrene-BODIPY; Styrene-Conjugated BODIPY) is a styrene-conjugated fluorescent probe used to measure the activity of radical-trapping antioxidants (RTAs)> .

HY-152231

BODIPY FL thalidomide	Fluorescent Dye Ligands for E3 Ligase	Others
BODIPY FL thalidomide is a high-affinity and selective human cereblon (CRBN)-targeting fluorescent probe with a K_d of 3.6 nM. BODIPY FL thalidomide enables use as a probe in time-resolved fluorescence resonance energy transfer (TR-FRET) binding assays for cereblon ligands. BODIPY FL thalidomide supports development of highly sensitive, selective, stable cereblon TR-FRET binding assays (Ex/Em = 502/510 nm) .

HY-D1602

BODIPY FL-DHPE	Fluorescent Dye	Others
BODIPY FL DHPE is a green-fluorescent phospholipid probe. BODIPY FL DHPE labels lipid 1,2-dihexadecanoyl-sn-glycero-phosphoethanolamine (DHPE), labeled liposomes can be internalized by membrane fusion. BODIPY FL DHPE can be used for investigations of membrane surface and membrane fusion. (λ_ex=505 nm, λ_em=511 nm) .

HY-D1459

BODIPY 665/676	Fluorescent Dye	Metabolic Disease
BODIPY 665/676 is a lipophilic radical-sensitive fluorescent probe that can be used to study radical-driven lipid autoxidation (Ex/Em=665/676 nm) .

HY-DY1073

MitoPerOx (solution)	Fluorescent Dye	Others
MitoPerOx (solution) is a mitochondrial-targeted, lipid peroxidation-indicating fluorescent probe with BODIPY581/591 fluorophores. The triphenylphosphine cation (TPP+) of MitoPerOx can be selectively enriched in mitochondria (depending on membrane potential) and can be used to detect lipid peroxidation in the inner mitochondrial membrane. Under the action of lipid peroxides, the BODIPY581/591 fluorophores of MitoPerOx shift their emission wavelength from 590 nm (reduced state) to 520 nm (oxidized state) , and ratiometric detection can be performed at an excitation wavelength of 488 nm. MitoPerOx can specifically monitor the peroxidation of mitochondrial phospholipids (especially cardiolipin) and is used in the study of oxidative stress-related diseases (such as aging, neurodegenerative diseases, and mitochondrial dysfunction) . Solvent and concentration: DMSO: 2 mM

HY-W248115

Pyrromethene 597	Fluorescent Dye	Others
Pyrromethene 597 is a BODIPY laser dye. Pyrromethene 597 displays wide tuning range of lasing wavelengths and high photostability. Pyrromethene 597 can be used as a thermal probe .

HY-114354

BODIPY FL alkyne BOD FL alkyne	Fluorescent Dye	Inflammation/Immunology
BODIPY (BOD) FL alkyne is an alkyne-containing *BODIPY* fluorophore derivative. BODIPY FL alkyne is a bioorthogonal labeling reagent with low toxicity and extremely low non-specific reactivity, and it is widely used in fluorescent bioimaging. BODIPY FL alkyne specifically labels azide groups on intracellular glycoconjugates mainly via strain-promoted azide-alkyne cycloaddition (SPAAC), or mediates site-specific conjugation with proteins such as IL-33, and supports positive cross-linking with other probes (e.g., DBCO-SCy5) for dual labeling. With the advantages of high specificity and low background interference, BODIPY FL alkyne can be used in the research of related diseases such as asthma, atopic dermatitis and inflammatory bowel disease .

HY-D1735

BODIPY TR Ceramide Golgi-Red Tracke	Fluorescent Dye	Others
The Golgi apparatus is composed of flattened vesicles superimposed on each other by unit membranes. The flattened vesicles are round with expanded and perforated edges. The Golgi fluorescent probe is a BODIPY-labeled ceramide derivative, the synthesis of which occurs in the endoplasmic reticulum and can then be transported to the Golgi via ceramide transport protein (CERT) or vesicular translocation, allowing specific labeling of the dye. BODIPY TR Ceramide (Golgi-Red Tracke) is a Golgi-specific fluorescent dye, which can visualise individual cells . Ex/Em=589 nm/616 nm.

HY-D1590

BODIPY Green 8-P2M	Fluorescent Dye	Others
ODIPY Green 8-P2M is a novel thiol-reactive fluorescence probe based on the BODIPY fluorophore, the fluorescence is strongly quenched by d-PeT and then can be restored after reaction with thiol, resulting in an extremely high signal-to-noise ratio. ODIPY Green 8-P2M can be useful for detecting extremely low concentrations of protein in the gel after SDS-PAGE .

HY-100335

PCI-33380 1 Publications Verification	Fluorescent Dye Btk	Cancer
PCI-33380 is a fluorescent probe ( (Ex=532 nm, Em=555 nm). PCI-33380 consists of a (BTK) inhibitor PCI-32765 (HY-10997) attaching with a Bodipy-FL fluorophore via a piperazine linker. PCI-33380 binds predominantly to Btk in B cell lysates with cell permeable activity. PCI-33380 can be used for imaging live cancer cells such as non-Hodgkin lymphoma research

HY-DY1074

ER-Tracker Blue-White DPX (solution)	Fluorescent Dye	Others
ER-Tracker dye is a derivative of BODIPY series dyes coupled with Glibenclamide (HY-15206) , highly selective binding to the endoplasmic reticulum, non-toxic to cells at low concentrations, this type of dye is an environmentally sensitive probe, and formaldehyde treatment can still retain part of the fluorescence, with high fluorescence life, good extinction coefficient and other characteristics. Glibenclamide is an atp-dependent K ⁺ channel blocker (Kir6, KATP) and CFTR Cl-channel blocker that binds in the endoplasmic reticulum. ER-Tracker is not suitable for staining fixed cells. Staining followed by fixation is possible, but cells fixed with aldehydes will only retain partial fluorescence . Solvent and concentration: DMSO: 1 mM

HY-D1262

BODIPY-TS Thiol-green 2	Fluorescent Dye	Others
BODIPY-TS (Thiol-green 2) is a fast response and thiol-specific turn-on probe. BODIPY-TS utilizes the thiosulfonate scaffold as a thiol recognition unit. BODIPY-TS has low toxicity, and features high selectivity, low detection limit, and quantitative reaction to thiols . Ex: 490 nM; Em: 515 nM.

HY-W089353

8-Phenyl-BODIPY 505/515 1 Publications Verification	MOFs Fluorescent Dye	Others
8-Phenyl-BODIPY 505/515 is a molecular rotor based on the *BODIPY* scaffold, specifically used as a microviscosity probe. The working principle of 8-Phenyl-BODIPY 505/515 is based on the restriction of molecular motion by viscosity: in a high-viscosity environment, the rotational freedom of its chemical bonds is inhibited, which leads to a significant extension of fluorescence lifetime. This property makes 8-Phenyl-BODIPY 505/515 an effective tool for monitoring changes in the viscosity of intracellular microenvironments via fluorescence lifetime imaging (FLIM) technology .

HY-D2415

BODIPY-FL staurosporine	Fluorescent Dye	Others
BODIPY-FL staurosporine (Compound 8a) is a fluorescence probe based on staurosporine, exhibiting high specificity towards tyrosine kinases (TK) and tyrosine kinase-like (TKL) family kinases. BODIPY-FL staurosporine has the potential to develop binding assays for kinases that are not recommended for use with Kinase Tracer 236, such as PIM3, CDC42BPG, MAP2K7, TXK, and SIK3. BODIPY-FL staurosporine can be a powerful tool for analyzing kinase selectivity in kinase drug discovery .

HY-147889

BBR-BODIPY	Apoptosis Caspase Bcl-2 Family	Others
BBR-BODIPY is a fluorescent probe that allows screening its interaction with the targeted cells. BBR-BODIPY induces apoptosis and changes the expression of apoptosis-related proteins .

HY-D2413

BODIPY FL VH032 Bodipy FL PEG4-VH032	Fluorescent Dye	Others
BODIPY FL VH032 is a high-affinity VHL fluorescent probe with a K_d value of 3.01 nM. BODIPY FL VH032 consists of von Hippel-Lindau (VHL) ligand VH032 (HY-120217) and BODIPY FL (HY-43520). BODIPY FL VH032 can be used for time-resolved fluorescence resonance energy transfer (TR-FRET) detection for high-throughput identification and characterization of VHL ligands with maximum excitation emission wavelength: 504/520 nm .

HY-N15875

18:1-18:1-C11 BODIPY 505/515 TG	Fluorescent Dye	Metabolic Disease
18:1-18:1-C11 BODIPY 505/515 TG is a fluorescently-labeled triglyceride that can be used as a fluorescent probe (Ex/Em = 495/503 nm).

HY-DY1043

ER-Tracker Green (solution)	Fluorescent Dye	Others
ER-Tracker dye is a derivative of BODIPY series dyes coupled with Glibenclamide (HY-15206) , highly selective binding to the endoplasmic reticulum, non-toxic to cells at low concentrations, this type of dye is an environmentally sensitive probe, and formaldehyde treatment can still retain part of the fluorescence, with high fluorescence life, good extinction coefficient and other characteristics. Glibenclamide is an atp-dependent K ⁺ channel blocker (Kir6, KATP) and CFTR Cl-channel blocker that binds in the endoplasmic reticulum. ER-Tracker is not suitable for staining cells after fixation . Solvent and concentration: DMSO: 1 mM

HY-D1726

8RK59	Deubiquitinase	Cancer
8RK59, a Bodipy probe, is a potent UCHL1 (ubiquitin C-terminal hydrolase L1) inhibitor, with an IC₅₀ close to 1 μM. 8RK59 could penetrate and label living cells. BodipyFL-alkyne is coupled to the azide of 8RK64 (HY-148254) using copper(I)-mediated click chemistry, resulting in compound 8RK59 .

HY-DY1026

ER-Tracker Red (solution)	Fluorescent Dye	Cancer
ER-Tracker dye is a derivative of BODIPY series dyes coupled with Glibenclamide (HY-15206) , highly selective binding to the endoplasmic reticulum, non-toxic to cells at low concentrations, this type of dye is an environmentally sensitive probe, and formaldehyde treatment can still retain part of the fluorescence, with high fluorescence life, good extinction coefficient and other characteristics. Glibenclamide is an atp-dependent K ⁺ channel blocker (Kir6, KATP) and CFTR Cl-channel blocker that binds in the endoplasmic reticulum. ER-Tracker is not suitable for staining cells after fixation. Ex/Em=587/615 nm . Solvent and concentration: DMSO: 1 mM

HY-D1595

BODIPY FL Cholesterol	Fluorescent Dye	Others
BODIPY FL Cholesterol is a green fluorescent, lipophilic probe. BODIPY FL Cholesterol can be used for the research of lipid transport processes and lipid-protein interactions .

HY-D1671

TRITC-DHPE	Fluorescent Dye	Others
TRITC-DHPE is a rhodamine-labeled glycerophosphate ethanolamine lipid, with head groups marked with bright red fluorescent TRITC dye (λEx/λEm=514/580 nm). TRITC-DHPE can be used for membrane fusion assay to trace lipid processing in intracellular phagocytosis. TRITC-DHPE can serves as an energy transfer receptor for NBD, BODIPY and fluorescein lipid probes .

HY-D2262

BODIPY-cholesterol conjugate-2	Fluorescent Dye	Metabolic Disease
BODIPY-cholesterol conjugate-2 (compound 6) is a BODIPY-cholesterol conjugate. BODIPY-cholesterol conjugate-2 is a useful probe for simultaneous visualization of intracellular cholesterol pools and for monitoring cholesterol efflux from cells to extracellular acceptors. (λex=589 nm, λem=638 nm) .

HY-D1591

BODIPY R6G methyl ester	Fluorescent Dye	Others
BODIPY R6G methyl ester (compound 5′-1) is a BODIPY-like fluorescent dye with good light stability and insensitive to pH value. BODIPY R6G methyl ester shows good photostability, high sensitivity and insensitive to pH value. BODIPY R6G methyl ester can be used in research areas such as photodynamic research, PH probes, ion recognition, photocatalysis, protein labeling, cell imaging, and proteomic analysis .

HY-D1609

BODIPY FL Verapamil hydrochloride	Fluorescent Dye	Others
BODIPY FL Verapamil hydrochloride is a fluorescent dye, it can be used as a molecular probe to label tissues and cells. BODIPY FL Verapamil hydrochloride is a substrate for both ABCB1 and ABCC1 .

HY-W248119

8-(4-Iodophenyl)-1,3,5,7-tetramethyl BODIPY	Fluorescent Dye	Others
8-(4-Iodophenyl)-1,3,5,7-tetramethyl BODIPY is a BODIPY derivative that can be used as a fluorescent probe for GFP-labeled muscarinic M1 receptor .

HY-D2952

BOCA-1-BG	Fluorescent Dye	Others
BOCA-1-BG is a BODIPY-labeled SNAP tag fluorescence probe. BOCA-1-BG can be used to detect Ca ²⁺ concentration and serves as a highly sensitive Ca ²⁺ fluorescent indicator .

HY-147177

Bodipy 8-chloromethane	Fluorescent Dye	Others
BODIPY-8-chloromethane is a fluorophore. BODIPY-8-chloromethane can be used as as a fluorescent probe .

HY-138241

PBD-BODIPY	Fluorescent Dye	Others
PBD-BODIPY is a probe for the spectrophotometric measurement of autoxidation reactions. Co-autoxidation of the PBD-BODIPY signal carrier and a hydrocarbon co-substrate can be quantified by monitoring loss of absorbance at 591 nm. PBD-BODIPY has been used to measure the activity of radical-trapping antioxidants in cell-free assays. It has also been used as a fluorescent probe for the detection of epoxidation activity.

HY-D2261

BODIPY-cholesterol conjugate-1	Fluorescent Dye	Metabolic Disease
BODIPY-cholesterol conjugate-1 (compound 5) is a BODIPY-cholesterol conjugate. BODIPY-cholesterol conjugate-1 is a useful probe for simultaneous visualization of intracellular cholesterol pools and for monitoring cholesterol efflux from cells to extracellular acceptors . (λex 541 nm, λem 615 nm).

HY-151536

meso-Benzothiazole-BODIPY 505/515	Fluorescent Dye	Neurological Disease
meso-Benzothiazole-BODIPY 505/515 is a boron dipyrromethenes (BODIPY) -based fluorescent probeBODIPY 505/515 can monitor cellular viscosity changes and autophagy. meso-Benzothiazole-BODIPY 505/515 can be used for the research of Alzheimer’s diseases, lysosomal storage diseases and neural degeneration diseases .

HY-D2290

Demethoxy-BODIPY TMR NHS ester	Fluorescent Dye	Others
Demethoxy-BODIPY TMR NHS ester is an amine-reactive fluorescent probe, and can be used for the labeling of proteins, peptides, and other molecules .

HY-D2201

Fluorescent ACKR3 antagonist 1	Fluorescent Dye	Cancer
Fluorescent ACKR3 antagonist 1(compound 18a) is a atypical chemokine receptor 3 antagonist .

HY-D2997

1,2-Dimethylpyridinium iodide-Bodipy	Fluorescent Dye	Cancer
1,2-Dimethylpyridinium iodide-Bodipy (Probe 1) is an H₂S fluorescent probe. Self-assembled 1,2-Dimethylpyridinium iodide-Bodipy exhibits highly efficient responsiveness to H₂S. The assembled form of 1,2-Dimethylpyridinium iodide-Bodipy emits near-infrared fluorescence at 718 nm upon H₂S activation .

HY-175074

C3 BODIPY Ganglioside GM1 (d18:1/3:0) ammonium	Fluorescent Dye	Others
C3 BODIPY Ganglioside GM1 (d18:1/3:0) ammonium is a fluorescently labeled GM1 ganglioside probe. C3 BODIPY Ganglioside GM1 (d18:1/3:0) ammonium can be used as a probe in biological experiments .

HY-D2942

BDP-V BG-BODIPY	Fluorescent Dye	Others
BDP-V BG-BODIPY is a SNAP tag fluorescent probe labeled with a BODIPY molecular motor. BDP-V BG-BODIPY contains a BODIPY molecular rotor that functions as a viscosity-sensitive fluorophore, which is highly responsive to local viscosity changes and enables the specific monitoring of the local microviscosity of proteins. BDP-V BG-BODIPY supports one-photon and two-photon imaging, with an excitation wavelength (Ex) of 488 nm (for one-photon excitation) and 850 nm (for two-photon excitation), and an emission wavelength (Em) of 500-600 nm .

HY-D3449

8-(9-Bromoanthracene)-BODIPY 505/515	Fluorescent Dye Reactive Oxygen Species (ROS)	Others
8-(9-Bromoanthracene)-BODIPY 505/515 is a fluorescence turn-on probe with selective fluorescence turn-on response towards hydroxyl radical. 8-(9-Bromoanthracene)-BODIPY 505/515 can be used to detect reactive oxygen/nitrogen species (ROS/RNS) . (Ex/Em = 505/515 nm)

HY-D3190

BODIPY−DOX	Fluorescent Dye Apoptosis	Inflammation/Immunology
BODIPY-DOX is a conjugate composed of *BODIPY* and Doxorubicin (HY-15142A), as well as a pH-activated fluorescent probe for M1 macrophages and an apoptosis inducer. BODIPY-DOX undergoes pH-induced hydrazone bond cleavage in acidic M1 macrophage phagosomes, thereby releasing cytotoxic Doxorubicin (Dox) and inhibiting the function of pro-inflammatory M1 macrophages. BODIPY-DOX highly selectively inhibits the production of relevant pro-inflammatory cytokines by mouse and human monocyte-derived M1 macrophages, while exerting minimal effects on M2 or unactivated macrophages. Therefore, BODIPY-DOX enables simultaneous fluorescent tracing, differentiation and elimination of specific macrophage subsets, and exhibits the potential to regulate tissue regeneration in zebrafish models .

HY-D3233

Ctrl-BDPS1	Fluorescent Dye	Others
Ctrl-BDPS1 is a BODIPY-based control probe that shows no response to copper ions (exhibiting two emission peaks at 575 nm and 708 nm; the maximum excitation wavelength is at 627 nm). Ctrl-BDPS1 has no fluorescent response to Cu ⁺ .

HY-D3230

FLCS1	Fluorescent Dye	Others
FLCS1 is a *BODIPY*-based Fluorescent probe and selective copper (I) ion binder (λ_ex = 630 nm, λ_emis = 660 nm). Binding of FLCS1 to copper (I) ions induces fluorescence turn-on. Addition of copper (I) to a methanolic solution of FLCS1 causes a slight red shift (4 nm) in the maximum absorption wavelength (λ_max) in the UV-Vis spectrum .

HY-100335R

PCI-33380 (Standard)	Fluorescent Dye Reference Standards Btk	Cancer
PCI-33380 (Standard) is the analytical standard of PCI-33380 (HY-100335). This product is intended for research and analytical applications. PCI-33380 is a fluorescent probe ( (Ex=532 nm, Em=555 nm). PCI-33380 consists of a (BTK) inhibitor PCI-32765 (HY-10997) attaching with a Bodipy-FL fluorophore via a piperazine linker. PCI-33380 binds predominantly to Btk in B cell lysates with cell permeable activity. PCI-33380 can be used for imaging live cancer cells such as non-Hodgkin lymphoma research

Cat. No.	Product Name	Type

HY-110210

BODIPY-FL NHS ester

Bodipy FL,SE

Fluorescent Dyes

BODIPY FL NHS ester (BODIPY FL, SE) is a cell membranes-penatrable amine-reactive fluorescent probe. The maximum excitation/emission wavelength of the BODIPY-FL NHS ester are 502/511 nm, respectively. BODIPY-FL NHS ester has high stability and is insensitive to the polarity, pH and type of solvent, and can maintain stable fluorescence properties under different environmental conditions. BODIPY-FL NHS ester can be used for the synthesis of protease substrates, live cell imaging, protein labeling and immunoassay .

HY-43520

BODIPY-FL	Fluorescent Dyes
BODIPY-FL is a green fluorescent dye that can be used to label probes or primers. BODIPY-FL fluorescence can be quenched after interacting with uniquely positioned guanine, making it useful for quantifying specific DNA or RNA molecules. The maximum absorption wavelength of BODIPY-FL is 505 nm, and the maximum emission wavelength is 513 nm .

HY-D1297

ER-Tracker Green

Maximum Cited Publications

6 Publications Verification

Fluorescent Dyes

ER-Tracker dye is a derivative of BODIPY series dyes coupled with Glibenclamide (HY-15206), highly selective binding to the endoplasmic reticulum, non-toxic to cells at low concentrations, this type of dye is an environmentally sensitive probe, and formaldehyde treatment can still retain part of the fluorescence, with high fluorescence life, good extinction coefficient and other characteristics. Glibenclamide is an atp-dependent K ⁺ channel blocker (Kir6, KATP) and CFTR Cl-channel blocker that binds in the endoplasmic reticulum. ER-Tracker is not suitable for staining cells after fixation .

HY-125623

MitoPerOx

3 Publications Verification

Fluorescent Dyes

MitoPerOx is a mitochondrial-targeted, lipid peroxidation-indicating fluorescent probe with BODIPY581/591 fluorophores. The triphenylphosphine cation (TPP+) of MitoPerOx can be selectively enriched in mitochondria (depending on membrane potential) and can be used to detect lipid peroxidation in the inner mitochondrial membrane. Under the action of lipid peroxides, the BODIPY581/591 fluorophores of MitoPerOx shift their emission wavelength from 590 nm (reduced state) to 520 nm (oxidized state), and ratiometric detection can be performed at an excitation wavelength of 488 nm. MitoPerOx can specifically monitor the peroxidation of mitochondrial phospholipids (especially cardiolipin) and is used in the study of oxidative stress-related diseases (such as aging, neurodegenerative diseases, and mitochondrial dysfunction)[1][2].

HY-D1431

ER-Tracker Red

4 Publications Verification

Fluorescent Dyes

HY-D1612

BODIPY FL C5-Ceramide

Fluorescent Dyes

The Golgi apparatus is composed of flattened vesicles superimposed on each other by unit membranes. The flattened vesicles are round with expanded and perforated edges. The Golgi fluorescent probe is a BODIPY-labeled ceramide derivative, the synthesis of which occurs in the endoplasmic reticulum and can then be transported to the Golgi via ceramide transport protein (CERT) or vesicular translocation, allowing specific labeling of the dye . BODIPY Fl C5-Ceramide is a Golgi-specific green fluorescent dye, which can visualise individual cells . Ex/Em= 505 nm/512 nm.

HY-N0729F

BODIPY-Linoleic acid	Fluorescent Dyes
BODIPY-Linoleic acid is a conjugate of the BODIPY fluorophore and Linoleic acid (HY-N0729) (C18:2) and is a lipid metabolism probe.

HY-D1429

ER-Tracker Blue-White DPX

Fluorescent Dyes

HY-115691

STY-BODIPY Styrene-Bodipy; Styrene-Conjugated Bodipy	Fluorescent Dyes
STY-BODIPY (Styrene-BODIPY; Styrene-Conjugated BODIPY) is a styrene-conjugated fluorescent probe used to measure the activity of radical-trapping antioxidants (RTAs)> .

HY-D1602

BODIPY FL-DHPE	Fluorescent Dyes
BODIPY FL DHPE is a green-fluorescent phospholipid probe. BODIPY FL DHPE labels lipid 1,2-dihexadecanoyl-sn-glycero-phosphoethanolamine (DHPE), labeled liposomes can be internalized by membrane fusion. BODIPY FL DHPE can be used for investigations of membrane surface and membrane fusion. (λ_ex=505 nm, λ_em=511 nm) .

HY-D1459

BODIPY 665/676	Fluorescent Dyes
BODIPY 665/676 is a lipophilic radical-sensitive fluorescent probe that can be used to study radical-driven lipid autoxidation (Ex/Em=665/676 nm) .

HY-DY1073

MitoPerOx (solution)

Fluorescent Dyes

MitoPerOx (solution) is a mitochondrial-targeted, lipid peroxidation-indicating fluorescent probe with BODIPY581/591 fluorophores. The triphenylphosphine cation (TPP+) of MitoPerOx can be selectively enriched in mitochondria (depending on membrane potential) and can be used to detect lipid peroxidation in the inner mitochondrial membrane. Under the action of lipid peroxides, the BODIPY581/591 fluorophores of MitoPerOx shift their emission wavelength from 590 nm (reduced state) to 520 nm (oxidized state) , and ratiometric detection can be performed at an excitation wavelength of 488 nm. MitoPerOx can specifically monitor the peroxidation of mitochondrial phospholipids (especially cardiolipin) and is used in the study of oxidative stress-related diseases (such as aging, neurodegenerative diseases, and mitochondrial dysfunction) .
Solvent and concentration: DMSO: 2 mM

HY-W248115

Pyrromethene 597	Fluorescent Dyes
Pyrromethene 597 is a BODIPY laser dye. Pyrromethene 597 displays wide tuning range of lasing wavelengths and high photostability. Pyrromethene 597 can be used as a thermal probe .

HY-114354

BODIPY FL alkyne

BOD FL alkyne

Fluorescent Dyes

BODIPY (BOD) FL alkyne is an alkyne-containing BODIPY fluorophore derivative. BODIPY FL alkyne is a bioorthogonal labeling reagent with low toxicity and extremely low non-specific reactivity, and it is widely used in fluorescent bioimaging. BODIPY FL alkyne specifically labels azide groups on intracellular glycoconjugates mainly via strain-promoted azide-alkyne cycloaddition (SPAAC), or mediates site-specific conjugation with proteins such as IL-33, and supports positive cross-linking with other probes (e.g., DBCO-SCy5) for dual labeling. With the advantages of high specificity and low background interference, BODIPY FL alkyne can be used in the research of related diseases such as asthma, atopic dermatitis and inflammatory bowel disease .

HY-D1735

BODIPY TR Ceramide

Golgi-Red Tracke

Fluorescent Dyes

The Golgi apparatus is composed of flattened vesicles superimposed on each other by unit membranes. The flattened vesicles are round with expanded and perforated edges. The Golgi fluorescent probe is a BODIPY-labeled ceramide derivative, the synthesis of which occurs in the endoplasmic reticulum and can then be transported to the Golgi via ceramide transport protein (CERT) or vesicular translocation, allowing specific labeling of the dye. BODIPY TR Ceramide (Golgi-Red Tracke) is a Golgi-specific fluorescent dye, which can visualise individual cells . Ex/Em=589 nm/616 nm.

HY-DY1074

ER-Tracker Blue-White DPX (solution)

Fluorescent Dyes

ER-Tracker dye is a derivative of BODIPY series dyes coupled with Glibenclamide (HY-15206) , highly selective binding to the endoplasmic reticulum, non-toxic to cells at low concentrations, this type of dye is an environmentally sensitive probe, and formaldehyde treatment can still retain part of the fluorescence, with high fluorescence life, good extinction coefficient and other characteristics. Glibenclamide is an atp-dependent K ⁺ channel blocker (Kir6, KATP) and CFTR Cl-channel blocker that binds in the endoplasmic reticulum. ER-Tracker is not suitable for staining fixed cells. Staining followed by fixation is possible, but cells fixed with aldehydes will only retain partial fluorescence .
Solvent and concentration: DMSO: 1 mM

HY-D1262

BODIPY-TS Thiol-green 2	Fluorescent Dyes
BODIPY-TS (Thiol-green 2) is a fast response and thiol-specific turn-on probe. BODIPY-TS utilizes the thiosulfonate scaffold as a thiol recognition unit. BODIPY-TS has low toxicity, and features high selectivity, low detection limit, and quantitative reaction to thiols . Ex: 490 nM; Em: 515 nM.

HY-W089353

8-Phenyl-BODIPY 505/515

1 Publications Verification

Fluorescent Dyes

8-Phenyl-BODIPY 505/515 is a molecular rotor based on the BODIPY scaffold, specifically used as a microviscosity probe. The working principle of 8-Phenyl-BODIPY 505/515 is based on the restriction of molecular motion by viscosity: in a high-viscosity environment, the rotational freedom of its chemical bonds is inhibited, which leads to a significant extension of fluorescence lifetime. This property makes 8-Phenyl-BODIPY 505/515 an effective tool for monitoring changes in the viscosity of intracellular microenvironments via fluorescence lifetime imaging (FLIM) technology .

HY-D2415

BODIPY-FL staurosporine

Fluorescent Dyes

BODIPY-FL staurosporine (Compound 8a) is a fluorescence probe based on staurosporine, exhibiting high specificity towards tyrosine kinases (TK) and tyrosine kinase-like (TKL) family kinases. BODIPY-FL staurosporine has the potential to develop binding assays for kinases that are not recommended for use with Kinase Tracer 236, such as PIM3, CDC42BPG, MAP2K7, TXK, and SIK3. BODIPY-FL staurosporine can be a powerful tool for analyzing kinase selectivity in kinase drug discovery .

HY-147889

BBR-BODIPY	Fluorescent Dyes
BBR-BODIPY is a fluorescent probe that allows screening its interaction with the targeted cells. BBR-BODIPY induces apoptosis and changes the expression of apoptosis-related proteins .

HY-D2413

BODIPY FL VH032

Bodipy FL PEG4-VH032

Fluorescent Dyes

BODIPY FL VH032 is a high-affinity VHL fluorescent probe with a K_d value of 3.01 nM. BODIPY FL VH032 consists of von Hippel-Lindau (VHL) ligand VH032 (HY-120217) and BODIPY FL (HY-43520). BODIPY FL VH032 can be used for time-resolved fluorescence resonance energy transfer (TR-FRET) detection for high-throughput identification and characterization of VHL ligands with maximum excitation emission wavelength: 504/520 nm .

HY-DY1043

ER-Tracker Green (solution)

Fluorescent Dyes

ER-Tracker dye is a derivative of BODIPY series dyes coupled with Glibenclamide (HY-15206) , highly selective binding to the endoplasmic reticulum, non-toxic to cells at low concentrations, this type of dye is an environmentally sensitive probe, and formaldehyde treatment can still retain part of the fluorescence, with high fluorescence life, good extinction coefficient and other characteristics. Glibenclamide is an atp-dependent K ⁺ channel blocker (Kir6, KATP) and CFTR Cl-channel blocker that binds in the endoplasmic reticulum. ER-Tracker is not suitable for staining cells after fixation .
Solvent and concentration: DMSO: 1 mM

HY-D1726

8RK59	Fluorescent Dyes
8RK59, a Bodipy probe, is a potent UCHL1 (ubiquitin C-terminal hydrolase L1) inhibitor, with an IC₅₀ close to 1 μM. 8RK59 could penetrate and label living cells. BodipyFL-alkyne is coupled to the azide of 8RK64 (HY-148254) using copper(I)-mediated click chemistry, resulting in compound 8RK59 .

HY-DY1026

ER-Tracker Red (solution)

Fluorescent Dyes

ER-Tracker dye is a derivative of BODIPY series dyes coupled with Glibenclamide (HY-15206) , highly selective binding to the endoplasmic reticulum, non-toxic to cells at low concentrations, this type of dye is an environmentally sensitive probe, and formaldehyde treatment can still retain part of the fluorescence, with high fluorescence life, good extinction coefficient and other characteristics. Glibenclamide is an atp-dependent K ⁺ channel blocker (Kir6, KATP) and CFTR Cl-channel blocker that binds in the endoplasmic reticulum. ER-Tracker is not suitable for staining cells after fixation. Ex/Em=587/615 nm .
Solvent and concentration: DMSO: 1 mM

HY-D1595

BODIPY FL Cholesterol	Fluorescent Dyes
BODIPY FL Cholesterol is a green fluorescent, lipophilic probe. BODIPY FL Cholesterol can be used for the research of lipid transport processes and lipid-protein interactions .

HY-D1671

TRITC-DHPE	Fluorescent Dyes
TRITC-DHPE is a rhodamine-labeled glycerophosphate ethanolamine lipid, with head groups marked with bright red fluorescent TRITC dye (λEx/λEm=514/580 nm). TRITC-DHPE can be used for membrane fusion assay to trace lipid processing in intracellular phagocytosis. TRITC-DHPE can serves as an energy transfer receptor for NBD, BODIPY and fluorescein lipid probes .

HY-D2262

BODIPY-cholesterol conjugate-2	Fluorescent Dyes
BODIPY-cholesterol conjugate-2 (compound 6) is a BODIPY-cholesterol conjugate. BODIPY-cholesterol conjugate-2 is a useful probe for simultaneous visualization of intracellular cholesterol pools and for monitoring cholesterol efflux from cells to extracellular acceptors. (λex=589 nm, λem=638 nm) .

HY-D1591

BODIPY R6G methyl ester

Fluorescent Dyes

BODIPY R6G methyl ester (compound 5′-1) is a BODIPY-like fluorescent dye with good light stability and insensitive to pH value. BODIPY R6G methyl ester shows good photostability, high sensitivity and insensitive to pH value. BODIPY R6G methyl ester can be used in research areas such as photodynamic research, PH probes, ion recognition, photocatalysis, protein labeling, cell imaging, and proteomic analysis .

HY-D1609

BODIPY FL Verapamil hydrochloride	Fluorescent Dyes
BODIPY FL Verapamil hydrochloride is a fluorescent dye, it can be used as a molecular probe to label tissues and cells. BODIPY FL Verapamil hydrochloride is a substrate for both ABCB1 and ABCC1 .

HY-W248119

8-(4-Iodophenyl)-1,3,5,7-tetramethyl BODIPY	Fluorescent Dyes
8-(4-Iodophenyl)-1,3,5,7-tetramethyl BODIPY is a BODIPY derivative that can be used as a fluorescent probe for GFP-labeled muscarinic M1 receptor .

HY-D2952

BOCA-1-BG	Fluorescent Dyes
BOCA-1-BG is a BODIPY-labeled SNAP tag fluorescence probe. BOCA-1-BG can be used to detect Ca ²⁺ concentration and serves as a highly sensitive Ca ²⁺ fluorescent indicator .

HY-147177

Bodipy 8-chloromethane	Fluorescent Dyes
BODIPY-8-chloromethane is a fluorophore. BODIPY-8-chloromethane can be used as as a fluorescent probe .

HY-D2921

BODIPY-FL-Vindoline	Fluorescent Dyes
BODIPY-FL-Vindoline is a high-affinity fluorescent probe for the pregnane X receptor (PXR), with a K_d of 256 nM. BODIPY-FL-Vindoline can be used in the research of drug metabolism and drug-drug interactions .

HY-D2290

Demethoxy-BODIPY TMR NHS ester	Fluorescent Dyes
Demethoxy-BODIPY TMR NHS ester is an amine-reactive fluorescent probe, and can be used for the labeling of proteins, peptides, and other molecules .

HY-D2201

Fluorescent ACKR3 antagonist 1	Fluorescent Dyes
Fluorescent ACKR3 antagonist 1(compound 18a) is a atypical chemokine receptor 3 antagonist .

HY-D2997

1,2-Dimethylpyridinium iodide-Bodipy	Fluorescent Dyes
1,2-Dimethylpyridinium iodide-Bodipy (Probe 1) is an H₂S fluorescent probe. Self-assembled 1,2-Dimethylpyridinium iodide-Bodipy exhibits highly efficient responsiveness to H₂S. The assembled form of 1,2-Dimethylpyridinium iodide-Bodipy emits near-infrared fluorescence at 718 nm upon H₂S activation .

HY-175074

C3 BODIPY Ganglioside GM1 (d18:1/3:0) ammonium	Fluorescent Dyes
C3 BODIPY Ganglioside GM1 (d18:1/3:0) ammonium is a fluorescently labeled GM1 ganglioside probe. C3 BODIPY Ganglioside GM1 (d18:1/3:0) ammonium can be used as a probe in biological experiments .

HY-D2942

BDP-V BG-BODIPY

Fluorescent Dyes

BDP-V BG-BODIPY is a SNAP tag fluorescent probe labeled with a BODIPY molecular motor. BDP-V BG-BODIPY contains a BODIPY molecular rotor that functions as a viscosity-sensitive fluorophore, which is highly responsive to local viscosity changes and enables the specific monitoring of the local microviscosity of proteins. BDP-V BG-BODIPY supports one-photon and two-photon imaging, with an excitation wavelength (Ex) of 488 nm (for one-photon excitation) and 850 nm (for two-photon excitation), and an emission wavelength (Em) of 500-600 nm .

HY-D3449

8-(9-Bromoanthracene)-BODIPY 505/515	Fluorescent Dyes
8-(9-Bromoanthracene)-BODIPY 505/515 is a fluorescence turn-on probe with selective fluorescence turn-on response towards hydroxyl radical. 8-(9-Bromoanthracene)-BODIPY 505/515 can be used to detect reactive oxygen/nitrogen species (ROS/RNS) . (Ex/Em = 505/515 nm)

HY-D3190

BODIPY−DOX

Fluorescent Dyes

BODIPY-DOX is a conjugate composed of BODIPY and Doxorubicin (HY-15142A), as well as a pH-activated fluorescent probe for M1 macrophages and an apoptosis inducer. BODIPY-DOX undergoes pH-induced hydrazone bond cleavage in acidic M1 macrophage phagosomes, thereby releasing cytotoxic Doxorubicin (Dox) and inhibiting the function of pro-inflammatory M1 macrophages. BODIPY-DOX highly selectively inhibits the production of relevant pro-inflammatory cytokines by mouse and human monocyte-derived M1 macrophages, while exerting minimal effects on M2 or unactivated macrophages. Therefore, BODIPY-DOX enables simultaneous fluorescent tracing, differentiation and elimination of specific macrophage subsets, and exhibits the potential to regulate tissue regeneration in zebrafish models .

HY-D3233

Ctrl-BDPS1	Fluorescent Dyes
Ctrl-BDPS1 is a BODIPY-based control probe that shows no response to copper ions (exhibiting two emission peaks at 575 nm and 708 nm; the maximum excitation wavelength is at 627 nm). Ctrl-BDPS1 has no fluorescent response to Cu ⁺ .

HY-D3230

FLCS1	Fluorescent Dyes
FLCS1 is a *BODIPY*-based Fluorescent probe and selective copper (I) ion binder (λ_ex = 630 nm, λ_emis = 660 nm). Binding of FLCS1 to copper (I) ions induces fluorescence turn-on. Addition of copper (I) to a methanolic solution of FLCS1 causes a slight red shift (4 nm) in the maximum absorption wavelength (λ_max) in the UV-Vis spectrum .

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