8-Phenyl-BODIPY 505/515
Based on 1 publication(s) in Google Scholar
8-Phenyl-BODIPY 505/515 is a molecular rotor based on the BODIPY scaffold, specifically used as a microviscosity probe. The working principle of 8-Phenyl-BODIPY 505/515 is based on the restriction of molecular motion by viscosity: in a high-viscosity environment, the rotational freedom of its chemical bonds is inhibited, which leads to a significant extension of fluorescence lifetime. This property makes 8-Phenyl-BODIPY 505/515 an effective tool for monitoring changes in the viscosity of intracellular microenvironments via fluorescence lifetime imaging (FLIM) technology.
For research use only. We do not sell to patients.
- Purity: 98.47%
- CAS No.: 194235-40-0
- Formula: C19H19BF2N2
- Molecular Weight:324.18
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) 8-Phenyl-BODIPY 505/515
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Biological Activity
8-Phenyl-BODIPY 505/515 detects a local microviscosity maximum 10-20 μm above untreated F1-4_ErbB2 cells, and this region of increased microviscosity shifts to the membrane surface in enzyme-treated F1-4_ErbB2 cells, confirming its association with extracellular matrix components[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
515
502
Chemical Information
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CAS No. 194235-40-0
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Appearance Solid
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Molecular Weight 324.18
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Formula C19H19BF2N2
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Color Orange to red
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SMILES
CC1=C([N-](C(C)=C1)[B+3]([F-])2[F-])C(C3=CC=CC=C3)=C(C(C)=C4)[N]2=C4C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Publications (1)
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Journal Impact Factor
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Most Recent
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iScience
2025 Jun 19;28(7):112954. PMID: 40687811
Solvent & Solubility
DMSO : 40 mg/mL (123.39 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (280 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.0847 mL | 15.4235 mL | 30.8471 mL | 77.1177 mL |
| 5 mM | 0.6169 mL | 3.0847 mL | 6.1694 mL | 15.4235 mL | |
| 10 mM | 0.3085 mL | 1.5424 mL | 3.0847 mL | 7.7118 mL | |
| 15 mM | 0.2056 mL | 1.0282 mL | 2.0565 mL | 5.1412 mL | |
| 20 mM | 0.1542 mL | 0.7712 mL | 1.5424 mL | 3.8559 mL | |
| 25 mM | 0.1234 mL | 0.6169 mL | 1.2339 mL | 3.0847 mL | |
| 30 mM | 0.1028 mL | 0.5141 mL | 1.0282 mL | 2.5706 mL | |
| 40 mM | 0.0771 mL | 0.3856 mL | 0.7712 mL | 1.9279 mL | |
| 50 mM | 0.0617 mL | 0.3085 mL | 0.6169 mL | 1.5424 mL | |
| 60 mM | 0.0514 mL | 0.2571 mL | 0.5141 mL | 1.2853 mL | |
| 80 mM | 0.0386 mL | 0.1928 mL | 0.3856 mL | 0.9640 mL | |
| 100 mM | 0.0308 mL | 0.1542 mL | 0.3085 mL | 0.7712 mL |
8-Phenyl-BODIPY 505/515 Related Classifications
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