133867-53-5
Chemical Structure
BODIPY FL C5-Ceramide
- CAS No.: 133867-53-5
- Formula:C34H54BF2N3O3
- Molecular Weight:601.62
IUPAC Name: 2-bromo-4,6-dichlorobenzo[d]thiazole
InChIKey: VRQLSQAURNRUHQ-VYPMXFAASA-N
SMILES: O=C(CCCCC1=CC=C2C=C3C(C)=CC(C)=[N]3[B+3]([F-])([N-]21)[F-])N[C@H]([C@@H](/C=C/CCCCCCCCCCCCC)O)CO
Biological Activity: The Golgi apparatus is composed of flattened vesicles superimposed on each other by unit membranes. The flattened vesicles are round with expanded and perforated edges. The Golgi fluorescent probe is a BODIPY-labeled ceramide derivative, the synthesis of which occurs in the endoplasmic reticulum and can then be transported to the Golgi via ceramide transport protein (CERT) or vesicular translocation, allowing specific labeling of the dye[1]. BODIPY Fl C5-Ceramide is a Golgi-specific green fluorescent dye, which can visualise individual cells[2]. Ex/Em= 505 nm/512 nm.
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BODIPY FL C5-Ceramide | 98.87% | The Golgi apparatus is composed of flattened vesicles superimposed on each other by unit membranes. The flattened vesicles are round with expanded and perforated edges. The Golgi fluorescent probe is a BODIPY-labeled ceramide derivative, the synthesis of which occurs in the endoplasmic reticulum and can then be transported to the Golgi via ceramide transport protein (CERT) or vesicular translocation, allowing specific labeling of the dye. BODIPY Fl C5-Ceramide is a Golgi-specific green fluorescent dye, which can visualise individual cells. Ex/Em= 505 nm/512 nm. | ||||||||||||||||||||
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- [1]. Alamudi SH, et al. Development of background-free tame fluorescent probes for intracellular live cell imaging. Nat Commun. 2016 Jun 20;7:11964. [Content Brief]
- [2]. Podgorny OV, et al. Isolation of single Chlamydia-infected cells using laser microdissection. J Microbiol Methods. 2015 Feb;109:123-8. [Content Brief]
Keywords