2740620-18-0
Chemical Structure
BODIPY FL thalidomide
- CAS No.: 2740620-18-0
- Formula:C37H43BF2N6O7
- Molecular Weight:732.58
IUPAC Name: N-(3-(dimethylamino)propyl)propionimidamide 4-methylbenzenesulfonate
InChIKey: CJILTFJYYOHLGA-UHFFFAOYSA-N
SMILES: O=C(COC1=CC=CC(C(N2C3C(NC(CC3)=O)=O)=O)=C1C2=O)NCCCCCCCCNC(CCC4=CC=C5C=C6C(C)=CC(C)=[N]6[B+3]([F-])([N-]54)[F-])=O
Biological Activity: BODIPY FL thalidomide is a high-affinity and selective human cereblon (CRBN)-targeting fluorescent probe with a Kd of 3.6 nM. BODIPY FL thalidomide enables use as a probe in time-resolved fluorescence resonance energy transfer (TR-FRET) binding assays for cereblon ligands. BODIPY FL thalidomide supports development of highly sensitive, selective, stable cereblon TR-FRET binding assays (Ex/Em = 502/510 nm)[1].
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BODIPY FL thalidomide | 99.18% | BODIPY FL thalidomide is a high-affinity and selective human cereblon (CRBN)-targeting fluorescent probe with a Kd of 3.6 nM. BODIPY FL thalidomide enables use as a probe in time-resolved fluorescence resonance energy transfer (TR-FRET) binding assays for cereblon ligands. BODIPY FL thalidomide supports development of highly sensitive, selective, stable cereblon TR-FRET binding assays (Ex/Em = 502/510 nm). | ||||||||||||||||||||
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