Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
Bromodomain-containing protein 4
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "Bromodomain-containing protein 4" in MCE Product Catalog:
4
4 Cited Publications
Cat. No.: HY-P7846
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: BRD4; Mitotic Chromosome-Associated protein; Bromodomain containing 4; Bromodomain-containing protein 4; HUNKI; Chromosome-Associated protein; HUNK1; Bromodomain-containing protein 4 Variant; MCAP; Bromodomain-containing 4; CAP; protein HUNK1; FSHRG4; BRD4 protein; Female Sterile Homeotic Related Gene 4; CDLS6
Species:
Human
Source:
E. coli
2
2 Cited Publications
Target:
Research Areas:
ZL0454 is a potent and selective Bromodomain-containing protein 4 (BRD4) inhibitor with an IC50 of 49 and 32 nM for BD1 and BD2.
Synonyms: AP1867-PEG2-JQ1; AP-PEG2-JQ1
Target:
Research Areas:
NICE-01 (AP1867-PEG2-JQ1; AP-PEG2-JQ1) is a bifunctional compound that bind to proteins in separate cellular compartments that can induce nuclear import of cytosolic cargoes, using nuclear-localized bromodomain-containing protein 4 (BRD4) as a “carrier” for co-import and nuclear trapping of cytosolic proteins .
Cat. No.: HY-W017851
CAS No.: 1198-97-6
Target:
Research Areas:
4-Phenyl-2-pyrrolidinone is a precursor and synthetic intermediate. 4-Phenyl-2-pyrrolidinone can be used as a precursor in the synthesis of compounds with anticonvulsant and nootropic activities and is an intermediate in the synthesis of bromodomain-containing protein 4 (BRD4) bromodomain 1 inhibitors .
Target:
Research Areas:
ZL0420 is a potent and selective bromodomain-containing protein 4 (BRD4) inhibitor with IC50 values of 27 nM against BRD4 BD1 and 32 nM against BRD4 BD2.
Research Areas:
BRD4/CK2-IN-1 is the first highly effective and oral active dual-target inhibitor of BRD4/CK2 (bromodomain-containing protein 4/casein kinase 2), with IC50s of 180 nM and 230 nM for BRD4 and CK2, respectively. BRD4/CK2-IN-1 has strong anticancer activity without obvious toxicities. BRD4/CK2-IN-1 induces apoptosis and autophagy-associated cell death in triple-negative breast cancer (TNBC)
Cat. No.: HY-112149A
CAS No.: 2229039-45-4
Target:
Research Areas:
(E/Z)-ZL0420 is a racemic compound of (Z)-ZL0420 and (E)-ZL0420 isomers. (E)-ZL0420 is a potent and selective bromodomain-containing protein 4 (BRD4) inhibitor with IC50 values of 27 nM against BRD4 BD1 and 32 nM against BRD4 BD2 .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
