2 Results for "

Bullatine A

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Bullatine A" in MCE Product Catalog:

Bullatine A
Bullatine A
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Cat. No.: HY-N5025
CAS No.: 1354-84-3
Category:  

Alkaloids Piperidine Alkaloids Ranunculaceae  Aconitum carmichaeli Debx. Plants Disease Research Fields Inflammation/Immunology

Target:  

P2X Receptor Apoptosis ERK p38 MAPK c-Myc NF-κB Reactive Oxygen Species (ROS)

Bullatine A, a diterpenoid alkaloid, is a potent P2X7 antagonist. Bullatine A possesses anti-rheumatic, anti-inflammatory and anti-nociceptive effects. Bullatine A inhibits ATP-induced BV-2 cell death/apoptosis and P2X receptor-mediated inflammatory responses. Bullatine A suppresses glioma cell growth by targeting SIRT6. Bullatine A specifically attenuates pain hypersensitivity in rats. Bullatine A attenuates LPS (HY-D1056)-induced systemic inflammatory response by inhibiting the ROS/JNK/NF-κB pathway in mice. Bullatine A improves despair behavior in Chronic chronic social defeat stress (CSDS) mice. Bullatine A can be used for the study of inflammation, glioblastoma (GBM) and depression .
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Neoline
Neoline
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1 Cited Publications
Cat. No.: HY-N0478
CAS No.: 466-26-2
Synonyms: Bullatine B
Category:  

Alkaloids Piperidine Alkaloids other families Plants

Target:  

Others

Neoline (Bullatine B) is the active ingredient of the active ingredient (PA), which can be used to cure the disease. Neoline Flow Suppression Nav1.7 Electrical Flow Control (VGSC), improve diabetes mechanical pain sensitivity. Neoline has a list of compounds that can be used, research on its use, and the quality of its processing during processing in pain .
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