1. Alkaloids
  2. Neoline

Neoline (Synonyms: Bullatine B)

Cat. No.: HY-N0478 Purity: ≥98.0%
Handling Instructions

Neoline, the active ingredient of processed aconite root (PA), alleviated oxaliplatin-induced peripheral neuropathy in mice. Neoline can be used as a marker compound to determine the quality of the PA products for the treatment of neuropathic pain.

For research use only. We do not sell to patients.

Neoline Chemical Structure

Neoline Chemical Structure

CAS No. : 466-26-2

Size Price Stock Quantity
5 mg USD 202 In-stock
Estimated Time of Arrival: December 31
10 mg USD 343 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

Neoline, the active ingredient of processed aconite root (PA), alleviated oxaliplatin-induced peripheral neuropathy in mice. Neoline can be used as a marker compound to determine the quality of the PA products for the treatment of neuropathic pain[1].

Molecular Weight

437.57

Formula

C₂₄H₃₉NO₆

CAS No.
SMILES
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (571.34 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2853 mL 11.4267 mL 22.8535 mL
5 mM 0.4571 mL 2.2853 mL 4.5707 mL
10 mM 0.2285 mL 1.1427 mL 2.2853 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 6.25 mg/mL (14.28 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 6.25 mg/mL (14.28 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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Keywords:

NeolineBullatine BOthersoxaliplatin-inducedperipheralneuropathyneuropathicpainInhibitorinhibitorinhibit

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Product Name:
Neoline
Cat. No.:
HY-N0478
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