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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
18 Results for "
C-IBS
" in MedChemExpress (MCE) Product Catalog:
Products (18)
18 Results for "C-IBS" in MCE Product Catalog:
1
1 Cited Publications
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Anticancer agent 73 (compound CIB-3b) is a anticancer agent, potently targeting TAR RNA-binding protein 2 (TRBP) and disrupts its interaction with Dicer. Anticancer agent 73 can rebalance the expression profile of oncogenic or tumor-suppressive miRNAs. Anticancer agent 73 suppresses the proliferation and metastasis of HCC in vitro and in vivo .
Cat. No.: HY-170791
CAS No.: 1082942-70-8
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CIB-L43 is an orally active TRBP inhibitor (KD = 4.78 nM) and enhances disruption of TRBP-Dicer interactions (IC50 = 2.34 μM). CIB-L43 suppresses oncogenic miR-21 biosynthesis, increasing PTEN and Smad7 expression and inhibiting AKT and TGF-β signaling, thereby reducing HCC cell proliferation and migration .
Cat. No.: HY-162558
CAS No.: 886536-76-1
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NCGC00351170 is an antiplatelet agent that disrupts the calcium and integrin-binding protein 1 (CIB1)-αIIbβ3 interaction. NCGC00351170 inhibits thrombin-induced human platelet aggregation .
Synonyms: BRL 24924
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Renzapride (BRL 24924), a substituted benzamide, is a full 5-HT4 receptor agonist with a Ki value of 115 nM. Renzapride (BRL 24924) is also a 5HT2b and 5HT3 receptor antagonist . Renzapride could be used for constipation predominant irritable bowel syndrome (C-IBS) study .
Cat. No.: HY-14147A
Purity: 98.06%
Synonyms: (S)-BRL 24924
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(S)-Renzapride ((S)-BRL 24924) is the isomer of HY-14147 Renzapride. Renzapride is a 5-HT4 receptor agonist with a Ki value of 115 nM. Renzapride also is a 5HT2b and 5HT3 receptor antagonist. Renzapride can be used for constipation predominant irritable bowel syndrome (C-IBS) study .
Cat. No.: HY-N8443
CAS No.: 126671-80-5
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Cat. No.: HY-RS02706
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CIB1 Human Pre-designed siRNA Set A contains three designed siRNAs for CIB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS02707
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CIB2 Human Pre-designed siRNA Set A contains three designed siRNAs for CIB2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS02708
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CIB3 Human Pre-designed siRNA Set A contains three designed siRNAs for CIB3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS19584
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Cib1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cib1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS19884
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Cib2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cib2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS26081
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Cib1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Cib1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS26384
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Cib2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Cib2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-N12194
CAS No.: 108050-26-6
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Cat. No.: HY-184448
CAS No.: 2963747-43-3
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Pyruvate Carboxylase (PC) Apoptosis Ferroptosis Caspase Bcl-2 Family PARP Glutathione Peroxidase
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CIB-Q22 is a potent pyruvate carboxylase (PC) inhibitor with an IC50 of 1.74 nM. CIB-Q22 suppresses hepatocellular carcinoma (HCC) cell proliferation, migration, and invasion. CIB-Q22 induces apoptosis and ferroptosis, promotes mitochondrial oxidative stress and dysfunction, inhibits glycolysis and anaplerotic flux, and reverses epithelial-mesenchymal transition (EMT). CIB-Q22 can be used for the study of hepatocellular carcinoma .
Cat. No.: HY-RS02709
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CIB4 Human Pre-designed siRNA Set A contains three designed siRNAs for CIB4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-N12193
CAS No.: 108050-28-8
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
