(S)-Renzapride
Based on 1 Customer Validation
(S)-Renzapride ((S)-BRL 24924) is the isomer of HY-14147 Renzapride. Renzapride is a 5-HT4 receptor agonist with a Ki value of 115 nM. Renzapride also is a 5HT2b and 5HT3 receptor antagonist. Renzapride can be used for constipation predominant irritable bowel syndrome (C-IBS) study.
For research use only. We do not sell to patients.
- Purity: 98.06%
- Formula: C16H22ClN3O2
- Molecular Weight:323.82
-
Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
-
GPCR/G Protein Compound Library
HY-L006
-
Neuronal Signaling Compound Library
HY-L013
-
Neurotransmitter Receptor Compound Library
HY-L062
-
Anti-Alzheimer's Disease Compound Library
HY-L069
-
Coagulation and Anti-coagulation Compound Library
HY-L136
-
Membrane Protein-targeted Compound Library
HY-L149
-
Membrane Receptor-targeted Compound Library
HY-L150
-
Bioactive Compound Library Max
HY-L181
-
MCE Bioactive Compound Library
HY-L001V
-
Bioactive Compound Library
HY-L001
-
High-Throughput Bioactive Compound Library
HY-L205
-
Lactylation Compound Library
HY-L249
All 5-HT Receptor Isoforms
More
Biological Activity
|
5-HT2B Receptor |
Chemical Information
-
Appearance Solid
-
Molecular Weight 323.82
-
Formula C16H22ClN3O2
-
Color White to off-white
-
SMILES
ClC1=C(N)C=C(OC)C(C(N[C@H]2CCN3CCC[C@H]2C3)=O)=C1
-
Synonyms
(S)-BRL 24924
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 35 mg/mL (108.08 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (272 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
Handling Instructions (2659 KB)
References
[1]. Camilleri M, et al. Effect of renzapride on transit in constipation-predominant irritable bowel syndrome. Clin Gastroenterol Hepatol. 2004;2(10):895-904. [Content Brief]
[2]. Scarpellini E, et al. Renzapride: a new drug for the treatment of constipation in the irritable bowel syndrome. Expert Opin Investig Drugs. 2008;17(11):1663-1670. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.0881 mL | 15.4407 mL | 30.8814 mL | 77.2034 mL |
| 5 mM | 0.6176 mL | 3.0881 mL | 6.1763 mL | 15.4407 mL | |
| 10 mM | 0.3088 mL | 1.5441 mL | 3.0881 mL | 7.7203 mL | |
| 15 mM | 0.2059 mL | 1.0294 mL | 2.0588 mL | 5.1469 mL | |
| 20 mM | 0.1544 mL | 0.7720 mL | 1.5441 mL | 3.8602 mL | |
| 25 mM | 0.1235 mL | 0.6176 mL | 1.2353 mL | 3.0881 mL | |
| 30 mM | 0.1029 mL | 0.5147 mL | 1.0294 mL | 2.5734 mL | |
| 40 mM | 0.0772 mL | 0.3860 mL | 0.7720 mL | 1.9301 mL | |
| 50 mM | 0.0618 mL | 0.3088 mL | 0.6176 mL | 1.5441 mL | |
| 60 mM | 0.0515 mL | 0.2573 mL | 0.5147 mL | 1.2867 mL | |
| 80 mM | 0.0386 mL | 0.1930 mL | 0.3860 mL | 0.9650 mL | |
| 100 mM | 0.0309 mL | 0.1544 mL | 0.3088 mL | 0.7720 mL |
(S)-Renzapride Related Classifications
HY-14147A Related Classifications
Powered by Bioz