100 Results for "

C17

" in MedChemExpress (MCE) Product Catalog:
Products (100)

100 Results for "C17" in MCE Product Catalog:

5
5 Cited Publications
Cat. No.: HY-149992
CAS No.: 2911609-80-6
Purity:  99.95%
Target:  

MyD88

Research Areas:  

Inflammation/Immunology Cancer

MyD88-IN-1 (Compound c17) is an orally active MyD88 inhibitor. MyD88-IN-1 inhibits the interaction of TLR4 and MyD88 and suppressed the NF-κB pathway. MyD88-IN-1 can be used in research of cancer and inflammatory .
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4
4 Cited Publications
Cat. No.: HY-N6953
CAS No.: 107390-08-9
Garcinone D is an activator of the STAT3/Cyclin D1 and Nrf2/HO-1 pathways, and an inhibitor of CDK2/CyclinE1 (IC50 for CDK2/CyclinE1 is 28.23 μM). Garcinone D promotes neural stem cell proliferation by activating STAT3 phosphorylation and Cyclin D1 expression and enhancing the Nrf2/HO-1 signaling pathway. In addition, Garcinone D blocks the tumor cell cycle by inhibiting CDK2/CyclinE1. Garcinone D can promote the proliferation of C17.2 neural stem cells and inhibit prostate and breast cancer .
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2
2 Cited Publications
Cat. No.: HY-P70422
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Granulocyte Colony-Stimulating Factor; G-CSF; Pluripoietin; Filgrastim; Lenograstim; CSF3; C17orf33; GCSF
Species:  
Source:  
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1
1 Cited Publications
Cat. No.: HY-N2116
CAS No.: 111047-30-4
Ginkgolic acid C17:1 is a fatty acid synthase (FAS) inhibitor with an IC50 of 10.5 µM. Ginkgolic acid C17:1 shows anti-tumor activity by inhibiting the phosphorylation of STAT3 and inducing apoptosis. Ginkgolic acid C17:1 can block the interaction between S-RBD and ACE2, and has anti-SARS-CoV-2-S pseudovirus activity. Ginkgolic acid C17:1 inhibits the biofilm formation of enterohemorrhagic Escherichia coli and Staphylococcus aureus .
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1
1 Cited Publications
Cat. No.: HY-P700083AF
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CSF-3; MGI-1G; GM-CSF beta; pluripoietin
Species:  
Source:  
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1
1 Cited Publications
Cat. No.: HY-P73073
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Granulocyte Colony-Stimulating Factor; G-CSF; CSF3; C17orf33
Species:  
Source:  
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Cat. No.: HY-115703
CAS No.: 67492-16-4
Synonyms: N-Heptadecanoyl-D-erythro-sphingosine
Research Areas:  

Metabolic Disease

C17 Ceramide (d18:1/17:0) (N-Heptadecanoyl-D-erythro-sphingosine) is a phospholipid internal standard. C17 Ceramide (d18:1/17:0) is used in studies of medium-chain acyl-CoA dehydrogenase deficiency (MCADD) .
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Cat. No.: HY-N0467
CAS No.: 63550-99-2
Synonyms: Dulcoside B
Rebaudioside C (Dulcoside B) is an orally effective natural sweetener that cannot pass the blood-brain barrier and selectively binds to human sweet taste receptors (TAS1R2/TAS1R3). The sweetness of Rebaudioside C is about 20-30 times that of sucrose, and its sweetness activity depends on the C-16/C-17 double bond structure and specific aglycones. The glycoside structure in the Rebaudioside C molecule can bind to the sweet taste receptor, activate the taste signal transduction pathway, and produce sweetness perception .
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Cat. No.: HY-P991598
CAS No.: 2304625-87-2
Synonyms: MOR12743; MOR03207

Research Areas:  

Inflammation/Immunology

MOR-106 (MOR12743) is a humanized anti-IL-17C IgG1 monoclonal antibody. MOR-106 inhibits the NF-κB signaling pathway by specifically binding to IL-17C (IC50 = 59 pM for human IL-17C, IC50 = 55 pM for mouse IL-17C). MOR-106 can effectively inhibit skin inflammation and reduce related inflammatory factors in animal models of psoriasis and atopic dermatitis .
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Cat. No.: HY-141632
CAS No.: 32164-02-6
Synonyms: Heptadecasphinganine
Target:  

Bacterial

Research Areas:  

Infection Neurological Disease

Sphinganine-C17 (Heptadecasphinganine) is a synthetic bioactive sphingolipid and an isomer of sphinganine. Sphinganine-C17 inhibits the growth of Candida glabrata and Candida albicans with a minimum bactericidal concentration (MBC) of 0.5 μg/mL for both. Sphinganine-C17 can be used as an internal standard for the chromatographic analysis of sphingosine compounds .
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Cat. No.: HY-W004290S
CAS No.: 1219804-81-5
Methyl heptadecanoate-d33 is the deuterium labeled Methyl heptadecanoate (HY-W004290). Methyl heptadecanoate (C17:0 methyl ester) is the methyl ester derivative of heptadecanoic acid (HY-W004284). Methyl heptadecanoate is used as an internal standard for quantitative calibration of fatty acids in GC-MS analysis .
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Cat. No.: HY-148430
CAS No.: 121768-39-6
Purity:  99.83%
Target:  

Cytochrome P450

Research Areas:  

Cancer

4-Pyridylmethyl adamantanecarboxamide (Compound 11) is an Aromatase inhibitor with an IC50 of 1.5 μM against hAromatase. 4-Pyridylmethyl adamantanecarboxamide inhibits the C17,20-lyase activity of testicular cytochrome P45017α with an IC50 of 1600 nM, and also inhibits the 17α-hydroxylase activity of this enzyme with an IC50 of 7700 nM. 4-Pyridylmethyl adamantanecarboxamide can be used in the research of prostate cancer .
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Cat. No.: HY-P990225
Anti-Mouse IL-12 p40 Antibody (C17.8) is a rat-derived anti-mouse IL-12 p40 IgG2a κ type antibody inhibitor. Anti-Mouse IL-12 p40 Antibody (C17.8) binds p40 subunit of IL-12. Anti-Mouse IL-12 p40 Antibody (C17.8) can be used for the researches of inflammation, immunology and metabolic disease, such as diabetes and arthritis .
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Cat. No.: HY-N7961
CAS No.: 102811-39-2
(E/Z)-Ginkgolic acid C17:2, isolated from Ginkgo biloba, can bind with human dihydroorotate dehydrogenase (DHODH) tightly .
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Cat. No.: HY-131676
CAS No.: 121999-64-2
Synonyms: SM (d18:1/17:0); Heptadecanoyl Sphingomyelin; N-Heptadecanoyl-D-erythro-Sphingosylphosphorylcholine
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

C17 Sphingomyelin is a synthetic derivative of sphingomyelin that has been used as an internal standard for the quantification of sphingomyelin.
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Cat. No.: HY-141630
CAS No.: 474923-27-8
Purity:  99.00%
Synonyms: D-erythro-Sphingosine-C17-1-phosphate
Target:  

Drug Derivative

Research Areas:  

Cancer

Sphingosine-1-phosphate d17:1 (D-erythro-Sphingosine-C17-1-phosphate) is a derivative of ceramide. Sphingosine-1-phosphate d17:1 can be used for the research of cancer .
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Cat. No.: HY-N2673
CAS No.: 41442-57-3
Synonyms: 5-n-Heptadecylresorcinol; AR-C17
5-Heptadecylresorcinol (AR-C17), a phenolic lipid component, is also an orally active mitochondrial protector. 5-Heptadecylresorcinol improves mitochondrial function via sirtuin3 signaling pathway, thus alleviates endothelial cell damage and apoptosis. 5-Heptadecylresorcinol induces sirtuin3-mediated autophagy. 5-Heptadecylresorcinol reduces the atherosclerotic plaques in the aortic root region of mice heart. 5-Heptadecylresorcinol can be used for research of atherosclerosis prevention and obesity .
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Cat. No.: HY-N7583
CAS No.: 854038-96-3
Norcaesalpinin E, a C-17-norcassane-type diterpene found in Caesalpinia crista, is a Plasmodium falciparum growth inhibitor with an IC50 of 90 nM. Norcaesalpinin E induces dose-dependent growth inhibition of Plasmodium falciparum. Norcaesalpinin E can be used for the research of malaria .
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Cat. No.: HY-69055
CAS No.: 58794-09-5
7-Bromoisoquinoline is a brominated isoquinoline and synthetic precursor that constructs the isoquinoline functional group at the C17 position of target molecules. 7-Bromoisoquinoline serves as a key synthetic intermediate for the synthesis of cortistatin A-derived anti-angiogenic steroidal analogs (e.g., 7-tributylstannyl isoquinoline). 7-Bromoisoquinoline .
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Cat. No.: HY-158655
CAS No.: 1071654-84-6
Synonyms: (3'-Sulfo)Galβ-Cer (d18:1/17:0); N-Heptadecanoyl sulfatide; C17 Sulfatide
Research Areas:  

Neurological Disease

C17 3'-Sulfo galactosylceramide (d18:1/17:0) is a member of the sulfatide class of glycolipids. C17 3'-Sulfo galactosylceramide (d18:1/17:0) can be used for the mass spectrometric quantitative urinary determination in metachromatic leukodystrophies .
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