63550-99-2
Chemical Structure
Rebaudioside C
Synonym(s): Dulcoside B
- CAS No.: 63550-99-2
- Formula:C44H70O22
- Molecular Weight:951.01
IUPAC Name: (2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl (4R,4aS,6aR,9S,11aR,11bS)-9-(((2S,3R,4S,5R,6R)-5-hydroxy-6-(hydroxymethyl)-4-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-3-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-4,11b-dimethyl-8-methylenetetradecahydro-6a,9-methanocyclohepta[a]naphthalene-4-carboxylate
InChIKey: QSRAJVGDWKFOGU-WBXIDTKBSA-N
SMILES: O[C@H]1[C@H](O)[C@@H](CO)O[C@@H](OC([C@@]2(C)[C@](CC[C@]3(CC4=C)[C@@]5([H])CC[C@]4(O[C@]6([H])O[C@H](CO)[C@@H](O)[C@H](O[C@]7([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)[C@H]6O[C@@]8([H])[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O8)C3)([H])[C@@]5(C)CCC2)=O)[C@@H]1O
Biological Activity: Rebaudioside C (Dulcoside B) is an orally effective natural sweetener that cannot pass the blood-brain barrier and selectively binds to human sweet taste receptors (TAS1R2/TAS1R3). The sweetness of Rebaudioside C is about 20-30 times that of sucrose, and its sweetness activity depends on the C-16/C-17 double bond structure and specific aglycones. The glycoside structure in the Rebaudioside C molecule can bind to the sweet taste receptor, activate the taste signal transduction pathway, and produce sweetness perception[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Rebaudioside C | 99.99% | Rebaudioside C (Dulcoside B) is an orally effective natural sweetener that cannot pass the blood-brain barrier and selectively binds to human sweet taste receptors (TAS1R2/TAS1R3). The sweetness of Rebaudioside C is about 20-30 times that of sucrose, and its sweetness activity depends on the C-16/C-17 double bond structure and specific aglycones. The glycoside structure in the Rebaudioside C molecule can bind to the sweet taste receptor, activate the taste signal transduction pathway, and produce sweetness perception. | ||||||||||||||||||||
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Rebaudioside C (Standard) | ≥98% | Rebaudioside C (Standard) is the analytical standard of Rebaudioside C. This product is intended for research and analytical applications. Rebaudioside C (Dulcoside B) is a natural sweetener that can be used in controlled diets for diabetic patients. | ||||||||||||||||||||
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Rebaudioside A | 98.0% | Rebaudioside A is an orally effective steviol glycoside with high sweetness. Rebaudioside A acts as an inhibitor of α-glucosidase with an IC50 value of 35.01 μg/mL. Rebaudioside A increases the ATP/ADP ratio in β cells in a glucose-dependent manner, thereby inhibiting KATP channels, leading to membrane depolarization, calcium influx, and ultimately stimulating insulin secretion. Rebaudioside A activates the SREBP signaling pathway by inhibiting HMGCR, the rate-limiting enzyme in cholesterol synthesis, resulting in increased expression of LDLR on the cell surface, thus promoting the uptake of LDL-C in the blood. Rebaudioside A can be used for studies on blood glucose and lipid regulation as well as anti-obesity. | ||||||||||||||||||||
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Stevioside (Standard) | 98.39% | Stevioside (Standard) is the analytical standard of Stevioside. This product is intended for research and analytical applications. Stevioside is an orally active sweetener that can be isolated from Stevia rebaudiana, with antihypertensive, antihyperglycemic, antioxidant, anti-inflammatory and anti-tumor activities. | ||||||||||||||||||||
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Rebaudioside S | Rebaudioside S is a minor steviol glycoside that can be isolated from the leaves of Stevia rebaudiana. | |||||||||||||||||||||
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Stevioside E | Stevioside E is a diterpenoid glycoside which can be extract from Stevia rebaudiana. | |||||||||||||||||||||
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Stevioside D | Stevioside D is a natural product. | |||||||||||||||||||||
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Rebaudioside G | 99.89% | Rebaudioside G is the minor constituent isolated from the leaves of Stevia rebaudiana Bertoni, used for sweeteners research. | ||||||||||||||||||||
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Rebaudioside J | Rebaudioside J is a diterpene glycoside that can be found in Stevia rebaudiana. | |||||||||||||||||||||
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Rebaudioside F | 99.88% | Rebaudioside F is a steviol glycoside isolated from Stevia rebaudiana leaves. is a new natural sweet ingredient. | ||||||||||||||||||||
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Rebaudioside E | 99.87% | Rebaudioside E is a steviol glycoside isolated from Stevia rebaudiana leaves. | ||||||||||||||||||||
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Dulcoside A (Standard) | ≥98% | Dulcoside A (Standard) is the analytical standard of Dulcoside A. This product is intended for research and analytical applications. Dulcoside A is a glycoside that can be isolated from Stevia rebaudiana that elicits sweet and bitter taste through activation of TAS1R. Dulcoside A also exhibits anti-inflammatory activity. | ||||||||||||||||||||
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References
- [1]. Prakash I, et al. Catalytic hydrogenation of the sweet principles of Stevia rebaudiana, Rebaudioside B, Rebaudioside C, and Rebaudioside D and sensory evaluation of their reduced derivatives. Int J Mol Sci. 2012 Nov 16;13(11):15126-36. [Content Brief]
- [2]. Yang Z, et al. Enzymatic Synthesis and Characterization of a Novel α-1→6-Glucosyl Rebaudioside C Derivative Sweetener. Biomolecules. 2019 Jan 14;9(1):27. [Content Brief]
