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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
29 Results for "
CDH1
" in MedChemExpress (MCE) Product Catalog:
Products (29)
29 Results for "CDH1" in MCE Product Catalog:
66
66 Publications Verification
Synonyms: Tripterine; Tripterin
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TAME is an inhibitor of anaphase-promoting complex/cyclosome (APC/C or APC), which binds to APC/C and prevents its activation by Cdc20 and Cdh1, produces mitotic arrest. TAME is not cell permeable [1] .
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TAME hydrochloride is an inhibitor of anaphase-promoting complex/cyclosome (APC/C or APC), which binds to APC/C and prevents its activation by Cdc20 and Cdh1, produces mitotic arrest. TAME hydrochloride is not cell permeable [1] .
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Cat. No.: HY-P990362
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Cat. No.: HY-RS02320
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CDH1 Human Pre-designed siRNA Set A contains three designed siRNAs for CDH1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23495
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Cdh1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Cdh1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS17051
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Cdh1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cdh1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-145268
CAS No.: 863761-17-5
SLEC-11 is a CDH1/E-cadherin modulator that potently inhibits cell death in E-cadherin-deficient cells (EC50=8.2 μM). SLEC-11 can be used to study potential synthetic lethal therapies for gastric cancer [1].
Cat. No.: HY-145269
CAS No.: 2761538-66-1
AL-GDa62 is a derivative of the CDH1/E-cadherin modulator SLEC-11 (HY-145268) and induces apoptosis in CDH1 -/- cells. AL-GDa62 has an EC50 of 3.2 μM and 2 μM for isogenic mammary epithelial cells MCF10A-WT (wild type) and mutant MCF10A-CDH1 -/-, respectively. AL-GDa62 specifically inhibits TCOF1, ARPC5, and UBC9, and suppresses SUMOylation at low micromolar concentrations [1].
Cat. No.: HY-13067G
CAS No.: 34157-83-0
Synonyms: Tripterine (GMP); Tripterin (GMP)
Cat. No.: HY-P700008
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Cadherin-1; CDH1; CAM 120/80; E-cadherin; CD324
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
