30 Results for "

CEACAM-1

" in MedChemExpress (MCE) Product Catalog:
Products (30)

30 Results for "CEACAM-1" in MCE Product Catalog:

  • Recombinant Proteins Recommended:
Cat. No.: HY-163028
CAS No.: 459789-75-4
Target:  

Tim3

Research Areas:  

Cancer

ML-T7 is a potent Tim-3 inhibitor. ML-T7 blocks Tim-3 interactions with PtdSer and CEACAM1. ML-T7 not only enhances the antitumor activity of adoptive transfer therapy with cytotoxic T lymphocytes (CTLs) and CAR T cells but also increases the effector function of T cell. ML-T7 promotes NK cells’ killing activity against tumor cells and DC antigen-presenting capacity. ML-T7 directly exerts antitumor efficacy in preclinical tumor models either alone or in combination with Nivolumab (HY-P9903A). ML-T7 can be used for tumor immunotherapy research [1].
Cat. No.: HY-155175
CAS No.: 1113126-49-0
Purity:  98.93%
Target:  

Tim3 IFNAR

Research Areas:  

Cancer

TIM-3-IN-2 is a TIM-3 inhibitor. TIM-3-IN-2 blocks the interactions of TIM-3 with PtdSer, CEACAM1 and Gal-9, and inhibits the immunosuppressive function of TIM-3. TIM-3-IN-2 restores IFNγ release from peripheral blood mononuclear cells. TIM-3-IN-2 inhibits the proliferation of acute myeloid leukemia cells. TIM-3-IN-2 can be used for the research of acute myeloid leukemia [1].
Cat. No.: HY-P990821

Target:  

Tim3

Research Areas:  

Inflammation/Immunology

Anti-Mouse TIM-3 Antibody (RMT3-23) is a kind of rat-derived anti-mouse TIM-3 IgG2a antibody inhibitor. Anti-Mouse TIM-3 Antibody (RMT3-23) blocks Tim-3 binding to phosphatidylserine (PtdSer) and carcinoembryonic antigen cell adhesion molecule 1 (CEACAM1). Anti-Mouse TIM-3 Antibody (RMT3-23) inhibits phagocytosis of apoptotic cells in peritoneal exudate Mac1+ cells. Anti-Mouse TIM-3 Antibody (RMT3-23) can be used for the researches of inflammation and immunology, such as rheumatoid arthritis [1] .
Cat. No.: HY-P990569
CAS No.: 1783801-93-3
Synonyms: MK-6018

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

CM-24 is a humanized antibody expressed in CHO cells, targeting CEACAM1/CD66a. The predicted molecular weight (MW) of CM-24 is 145 kDa. The isotype control for CM-24 can refer to Human IgG1 kappa, Isotype Control (HY-P99001).
Cat. No.: HY-159884
CAS No.: 328540-44-9
Target:  

Tim3 TNF Receptor IFNAR

Research Areas:  

Cancer

MG-T-19 is a potent small-molecule inhibitor targeting human TIM-3. MG-T-19 blocks the interactions between TIM-3 and its ligands such as phosphatidylserine, CEACAM1 and Galectin-9. MG-T-19 promotes the secretion of TNF-α and IFN-γ by peripheral blood mononuclear cells, and significantly enhances their ability to inhibit cancer cell proliferation. MG-T-19 can be used in studies related to acute myeloid leukemia [1] .
Cat. No.: HY-P991198

Target:  

Tim3

Research Areas:  

Cancer

M6903 is a humanized monoclonal IgG2 antibody targeting T cell immunoglobulin and mucin domain-3 (TIM-3) (KD for human TIM-3 is 2.3 nM). M6903 binds to TIM-3, blocking the binding of TIM-3 to phosphatidylserine (PtdSer), carcinoembryonic antigen cell adhesion-related molecule 1 (CEACAM1), and galectin 9 (Gal-9), thus relieving TIM-3-mediated T cell inhibition and exerting the activities of activating antigen-specific T cells and enhancing anti-tumor immunity. M6903 is promising for research of cancers [1].
Cat. No.: HY-P990004

Target:  

Tim3

Research Areas:  

Inflammation/Immunology Cancer

Anti-Mouse TIM-3 Antibody (B8.2C12) is an anti-mouse TIM-3 IgG1 monoclonal antibody. Anti-Mouse TIM-3 Antibody (B8.2C12) can block the binding of Tim-3 with Phosphatidylserine (PtdSer) and CEACAM1 without interfering with the binding to Galectin-9. Anti-Mouse TIM-3 Antibody (B8.2C12) can inhibit tumor growth and activate tumor infiltrating CD8 + T cells. Anti-Mouse TIM-3 Antibody (B8.2C12) can be used for studying cancer such as breast cancer and colon cancer and constructing experimental autoimmune encephalomyelitis (EAE) models [1] .
Cat. No.: HY-RS02435
Research Areas:  

Others

CEACAM1 Human Pre-designed siRNA Set A contains three designed siRNAs for CEACAM1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Cat. No.: HY-RS17387
Research Areas:  

Others

Ceacam1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ceacam1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Cat. No.: HY-RS23842
Research Areas:  

Others

Ceacam1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ceacam1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Cat. No.: HY-P990364

Research Areas:  

Inflammation/Immunology

Anti-CEACAM1/CD66a Antibody is a human antibody expressed in CHO cells that targets CEACAM1/CD66a. The Anti-CEACAM1/CD66a Antibody is equipped with huIgG1 heavy chain and huκ light chain, with a predicted molecular weight (MW) of 144.98 kDa. The isotype control for the Anti-CEACAM1/CD66a Antibody can refer to Human IgG1 kappa, Isotype Control (HY-P99001).
Cat. No.: HY-P990854

Research Areas:  

Cancer

Anti-CEACAM1/3/5/6/8 Antibody (6G5j) is a kind of mouse IgG1 κ chimeric antibody, targeting to human CEACAM1/3/5/6/8. Anti-CEACAM1/3/5/6/8 Antibody (6G5j) reacts with an antigen epitope shared by human carcinoembryonic antigen-related cell adhesion molecule (CEACAM) 1, 3, 5, 6, and 8. Anti-CEACAM1/3/5/6/8 Antibody (6G5j) can be used for the detections of western blot, ELISA, immunofluorescence immunohistochemistry and flow cytometry in cancer [1].
Cat. No.: HY-P84091
Synonyms: CEACAM1; BGP; BGP1; BGPI; CD66a

Host:  

Mouse

Application:  

WB, IHC-P, FC, ELISA

Reactivity:  

Human

Cat. No.: HY-P84091A
Synonyms: CEACAM1; BGP; BGP1; BGPI; CD66a

Host:  

Mouse

Application:  

WB, IHC-P, FC, ELISA

Reactivity:  

Human

Cat. No.: HY-P77630
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: BGP; BGP1; BGPI; CEACAM1; CD66a
Species:  
Source:  
Cat. No.: HY-P78894
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CEACAM1; CD66a; BGP; BGP1; BGPI
Species:  
Source:  
Cat. No.: HY-P72695
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Carcinoembryonic antigen-related cell adhesion molecule 1; BGP-1; CD66a; CEACAM1
Species:  
Source:  
Cat. No.: HY-P72932
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Carcinoembryonic antigen-related cell adhesion molecule 1; BGP-1; CD66a; CEACAM1
Species:  
Source:  
Cat. No.: HY-P700975
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: BGP; BGP1; BGPI; CEACAM1; CD66a
Species:  
Source:  
Cat. No.: HY-P80985
Synonyms: BGP-1; BGPI; CD66a; CEACAM1

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, IP

Reactivity:  

Human