1 Result for "

Cassialoin

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "Cassialoin" in MCE Product Catalog:

Cassialoin
Cassialoin
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Cat. No.: HY-N21609
CAS No.: 60462-09-1
Category:  

Flavonoids Senna garrettiana (Craib) H.S.Irwin & Barneby Plants Fabaceae Isoflavones

Target:  

Drug Intermediate IFNAR

Cassialoin is an orally active anthrone-C-glucoside natural product with antitumor activity, which is found in the heartwood of Cassia garrettiana. Cassialoin is metabolized to the active substance Chrysophanol‑9‑anthrone. Cassialoin does not directly inhibit the activities of VEGFR‑2 and MMP‑9 in vitro, nor does it directly inhibit vascular lumen formation and cell migration in vitro. Cassialoin increases the number of IFN-γ-positive CD8 + T cells and natural killer cells in the small intestine or spleen, and enhances IFN-γ production by splenocytes induced by Concanavalin A (HY-P2149). Cassialoin inhibits tumor growth and peritoneal invasion in colon cancer xenograft models. Cassialoin can be used for research on colon cancer .
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