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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
18 Results for "
Chronic schizophrenia
" in MedChemExpress (MCE) Product Catalog:
Products (18)
18 Results for "Chronic schizophrenia" in MCE Product Catalog:
22
22 Publications Verification
Cat. No.: HY-14538B
CAS No.: 53515-91-6
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Haloperidol lactate is a potent antipsychotic agent. Haloperidol lactate can be used in acute and chronic schizophrenia and gilles de la tourette's syndrome. Haloperidol lactate has the potential for the research of psychotic disorders .
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Penfluridol (R-16341) is a potent, long-acting, first-generation, oral diphenylbutylpiperidine antipsychotic agent by targeting D2-like dopamine receptor. Penfluridol effectively inhibits TNFα-induced NF-κB activation and alleviates the severity of arthritis and colitis in vivo. Penfluridol is a Ca2+-calmodulin inhibitor. Penfluridol induces apoptosis and autophagy. Penfluridol is used for chronic schizophrenia, acute psychosis, Tourette syndrome and autoimmune diseases. Penfluridol inhibites the growth of E. faecalis planktonic cells with the MIC of 7.81 μg/ml .
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2 Cited Publications
Synonyms: HMPG; MHPG; MOPEG
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GSK239512 is a blood-brain barrier-permeable, orally active H3 receptor antagonist, with a human pKi ranging from <5.5 to 9.92 and a murine pKi ranging from 9.44 to 9.83. GSK239512 modulates cholinergic and monoaminergic neurotransmission, blocks the inhibitory feedback of H3 receptors, and increases the release of pro-cognitive neurotransmitters. GSK239512 induces oligodendrocyte precursor cell differentiation and restores myelin gene expression at the cellular level. GSK239512 reverses Scopolamine (HY-N0296)-induced memory deficits and improves recognition memory in animal models. GSK239512 can be used in research related to Alzheimer's disease, chronic traumatic encephalopathy, relapsing-remitting multiple sclerosis, and schizophrenia .
Synonyms: AHR 2277 free base
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Lenperone (AHR 2277 free base) has antipsychotic effect. Lenperone improves depressive symptoms .
Synonyms: HMPG-d3; MHPG-d3; MOPEG-d3
Cat. No.: HY-113323A
CAS No.: 28700-49-4
Synonyms: HMPG sulfate; MHPG sulfate; MOPEG sulfate
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3-Methoxy-4-hydroxyphenylglycol sulfate (HMPG sulfate) is a metabolite of norepinephrine degradation in the brain. 3-Methoxy-4-hydroxyphenylglycol sulfate is an indicators of central nervous system noradrenergic activity. 3-Methoxy-4-hydroxyphenylglycol sulfate can be used for research of depression, chronic schizophrenia, etc .
Cat. No.: HY-P5857
Synonyms: Micrurotoxin 2
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Carphenazine dimaleate is a Phenothiazine (HY-Y0055) class antipsychotic active molecule. Carphenazine can be used in research on chronic schizophrenia .
Cat. No.: HY-B1077R
CAS No.: 26864-56-2
Synonyms: R-16341 (Standard)
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Penfluridol (Standard) is the analytical standard of Penfluridol. This product is intended for research and analytical applications. Penfluridol (R-16341) is a potent, long-acting, first-generation, oral diphenylbutylpiperidine antipsychotic agent by targeting D2-like dopamine receptor. Penfluridol effectively inhibits TNFα-induced NF-κB activation and alleviates the severity of arthritis and colitis in vivo. Penfluridol is a Ca2+-calmodulin inhibitor. Penfluridol induces apoptosis and autophagy. Penfluridol is used for chronic schizophrenia, acute psychosis, Tourette syndrome and autoimmune diseases. Penfluridol inhibites the growth of E. faecalis planktonic cells with the MIC of 7.81 μg/ml .
Cat. No.: HY-143390
CAS No.: 2758255-05-7
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NMDA receptor modulator 2 (Compound 1) is a potent NMDA receptor modulator. NMDA receptor modulator 2 can be used for neurological disorder research .
Cat. No.: HY-143391
CAS No.: 2758256-02-7
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NMDA receptor modulator 3 (Compound 99) is a potent NMDA receptor modulator. NMDA receptor modulator 3 can be used for neurological disorder research .
Cat. No.: HY-143393
CAS No.: 2758256-71-0
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NMDA receptor modulator 4 (Compound 169) is a potent NMDA receptor modulator. NMDA receptor modulator 4 can be used for neurological disorder research .
Cat. No.: HY-143396
CAS No.: 2758256-97-0
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NMDA receptor modulator 5 (Compound 195) is a potent NMDA receptor modulator. NMDA receptor modulator 5 can be used for neurological disorder research .
Cat. No.: HY-143397
CAS No.: 2758256-85-6
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NMDA receptor modulator 6 (Compound 183) is a potent NMDA receptor modulator. NMDA receptor modulator 6 can be used for neurological disorder research .
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Azacyclonol (γ-pipradol) hydrochloride is a compound with promising anticancer activity, showing effectiveness in inhibiting NOX-derived ROS in A549 human lung cancer cells. Azacyclonol hydrochloride exhibits enhanced proliferation inhibition against androgen-refractory cancer cell lines, specifically DU145 and PC-3. Azacyclonol hydrochloride demonstrates antitumor activity in DU145-xenografted chorioallantoic membrane tumor models. Azacyclonol hydrochloride also acts as a ligand for the M3 muscarinic acetylcholine receptor, which is overexpressed in ARPC. Azacyclonol hydrochloride effectively blocks carbachol-induced proliferation and NOX activity in DU145 cells. Azacyclonol hydrochloride can also be utilized for the treatment of chronic schizophrenia.
Cat. No.: HY-119800
CAS No.: 86487-64-1
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Setoperone is an orally active and potent 5-HT₂ receptor antagonist and a moderate dopamine D₂ receptor blocker. Setoperone dissociates from the receptors relatively quickly, but it is easily "captured" by serotonin receptors in the body, resulting in persistent receptor inhibition even after elution. Setoperone can be used to study the negative symptoms of type II schizophrenia and associated mood disorders .
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Methopromazine maleate is a dopamine D2 receptor (Dopamine D2 receptor) antagonist belonging to the phenothiazine class of compounds, with an LD50 of 366 mg/kg in mouse studies. Methopromazine maleate competitively binds to and blocks G-protein coupled receptors (GPCR) in the central nervous system, thereby inhibiting downstream signal transduction. Methopromazine maleate can be used in research on chronic schizophrenia .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
