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Cat. No.: HY-187043

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Methopromazine maleate

Name: Methopromazine maleate
Brand: MedChemExpress
SKU: HY-187043
Availability: PreOrder

(Synonyms: Mopazine maleate)

Methopromazine maleate is a dopamine D2 receptor (Dopamine D2 receptor) antagonist belonging to the phenothiazine class of compounds, with an LD₅₀ of 366 mg/kg in mouse studies. Methopromazine maleate competitively binds to and blocks G-protein coupled receptors (GPCR) in the central nervous system, thereby inhibiting downstream signal transduction. Methopromazine maleate can be used in research on chronic schizophrenia.

For research use only. We do not sell to patients.

CAS No.: 3403-42-7
Formula: C₂₂H₂₆N₂O₅S
Molecular Weight:430.52

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Methopromazine maleate Chemical Structure

CAS No.: 3403-42-7

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Description

IC₅₀ & Target^[1]

D₂ Receptor

All Dopamine Receptor Isoforms :

Chemical Information

CAS No. 3403-42-7
Molecular Weight 430.52
Formula C₂₂H₂₆N₂O₅S
SMILES

CN(C)CCCN1C2=CC(OC)=CC=C2SC3=CC=CC=C31.OC(/C=C\C(O)=O)=O
Synonyms

Mopazine maleate
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Esteki M, et al. Mechanistic-based descriptors for QSAR study of psychotropic drug toxicity. Chemical biology & drug design. 2008 Nov;72(5):409-35.

[2]. BRADLEY PB, et al. The effect of chlorpromazine and methopromazine on the electrical activity of the brain in the cat. Electroencephalogr Clin Neurophysiol. 1957 May;9(2):191-215.

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
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Chemical Information
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References

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Methopromazine maleate

All Dopamine Receptor Isoforms