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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
655 Results for "
Class D
" in MedChemExpress (MCE) Product Catalog:
Products (655)
655 Results for "Class D" in MCE Product Catalog:
53
53 Publications Verification
CB-5083 is a first-in-class, potent, selective, and orally bioavailable inhibitor of the p97 AAA ATPase/VCP. CB-5083 selectively inhibits p97 through its D2 site with the IC50 of 11 nM .
6
Durlobactam sodium salt (ETX2514) is a broad-spectrum β-lactamase inhibitor with IC50s of 4, 14 and 190 nM for Class A KPC-2, Class C AmpC and Class D OXA-24, respectively. For the treatment of drug-resistant Gram-negative bacteria including Acinetobacter baumannii .
5
5 Cited Publications
Target:
Forschungsgebiete:
O-304 is a first-in-class, orally available pan-AMPK activator, which increases AMPK activity by suppressing the dephosphorylation of pAMPK. O-304 exhibits a great potential as a agent to treat type 2 diabetes (T2D) and associated cardiovascular complications .
3
3 Cited Publications
Target:
Forschungsgebiete:
LEI-401 is a first-in-class, selective, and CNS-active NAPE-PLD (N-acylphosphatidylethanolamine phospholipase D) inhibitor, with an IC50 of 27 nM. LEI-401 modulates emotional behavior in mice .
2
2 Cited Publications
Art. -Nr.: HY-P80900
Synonyms: SREBF1; BHLHD1; SREBP1; Sterol regulatory element-binding protein 1; SREBP-1; Class D basic helix-loop-helix protein 1; bHLHd1; Sterol regulatory element-binding transcription factor 1
1
Target:
Forschungsgebiete:
Levosulpiride (RV-12309) is the (S)-enantiomer of sulpiride, which is a D2 receptor a antagonist, an atypical antipsychotic agent of the benzamide class.
1
1 Cited Publications
Art. -Nr.: HY-B0150S
CAS. Nr.: 347841-88-7
Synonyms: Niacinamide-d4; Nicotinic acid amide-d4
1
1
Synonyms: 9β,10α-Cholesta-5,7-dien-3β-ol; Cholecalciferol EP Impurity C
Category:
Human Gut Microbiota Metabolites Metabolic Disease Endogenous metabolite Disease Research Fields Steroids
Target:
Target:
Art. -Nr.: HY-P4193
CAS. Nr.: 181272-91-3
Target:
Forschungsgebiete:
Art. -Nr.: HY-13666S
CAS. Nr.: 1246819-64-6
Synonyms: (-)-Tetramisole-d5 hydrochloride
Art. -Nr.: HY-W047710
CAS. Nr.: 21193-75-9
Target:
Forschungsgebiete:
BLI-489 hydrate, a penem β-lactamase inhibitor, is active against class A and class C as well as some class D β-lactamases. The combination of Piperacillin and BLI-489 hydrate is efficacious against murine infections caused by class A (including extended-spectrum β-lactamases), class C (AmpC), and class D β-lactamase-expressing pathogens .
Art. -Nr.: HY-112251GL
CAS. Nr.: 1224606-06-7
Target:
Forschungsgebiete:
WCK-4234 is a diazabicyclooctane β-lactamase inhibitor and susceptibility restorer. WCK-4234 lacks direct antibacterial activity. WCK-4234 inhibits class A, C, D β-lactamases and extended-spectrum β-lactamases to potentiate Imipenem (HY-B1369A) and Meropenem (HY-13678) activity against Gram-negative pathogens. WCK-4234 can be used for the research of gram-negative bacterial infections and β-lactamase-mediated carbapenem-resistant bacterial infections .
Art. -Nr.: HY-132824
CAS. Nr.: 1842399-68-1
Synonyms: VNRX-7145
Target:
Forschungsgebiete:
Ledaborbactam etzadroxil (VNRX-7145) is an orally active Ambler class A, C, and D β-lactamase enzymes inhibitor .
Art. -Nr.: HY-W008216S
CAS. Nr.: 1015855-78-3
Synonyms: Hydroxy Dimetridazole-d3
Art. -Nr.: HY-B0176AS
CAS. Nr.: 1330180-66-9
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
