2393840-15-6
2393840-15-6
Chemical Structure
LEI-401
- CAS No.: 2393840-15-6
- Formula:C24H31N5O2
- Molecular Weight:421.54
IUPAC Name: N-(cyclopropylmethyl)-6-((S)-3-hydroxypyrrolidin-1-yl)-2-((S)-3-phenylpiperidin-1-yl)pyrimidine-4-carboxamide
InChIKey: GFHJYPQZBBHOCC-UXHICEINSA-N
SMILES: O=C(C1=NC(N2C[C@H](C3=CC=CC=C3)CCC2)=NC(N4C[C@@H](O)CC4)=C1)NCC5CC5
Biological Activity: LEI-401 is a first-in-class, selective, and CNS-active NAPE-PLD (N-acylphosphatidylethanolamine phospholipase D) inhibitor, with an IC50 of 27 nM. LEI-401 modulates emotional behavior in mice[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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LEI-401 | 99.73% | LEI-401 is a first-in-class, selective, and CNS-active NAPE-PLD (N-acylphosphatidylethanolamine phospholipase D) inhibitor, with an IC50 of 27 nM. LEI-401 modulates emotional behavior in mice. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.47
HY-173562PRMT5 ligand 2 -
Similarity Score 0.47
HY-101563Pemrametostat -
Similarity Score 0.47
HY-176063TRPV1 antagonist 11 -
Similarity Score 0.46
HY-18779PF-4840154 -
Similarity Score 0.46
HY-12727EPZ015666 -
Similarity Score 0.46
HY-182385BPN-14136 -
Similarity Score 0.46
HY-173092PRMT5 ligand 1 -
Similarity Score 0.45
HY-49421BTK ligand 12 -
Similarity Score 0.45
HY-172796UNC9435 -
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