2393840-15-6

LEI-401 Chemical Structure
2393840-15-6

Chemical Structure

LEI-401

  • CAS No.: 2393840-15-6
  • Formula:C24H31N5O2
  • Molecular Weight:421.54

IUPAC Name: N-(cyclopropylmethyl)-6-((S)-3-hydroxypyrrolidin-1-yl)-2-((S)-3-phenylpiperidin-1-yl)pyrimidine-4-carboxamide

InChIKey: GFHJYPQZBBHOCC-UXHICEINSA-N

SMILES: O=C(C1=NC(N2C[C@H](C3=CC=CC=C3)CCC2)=NC(N4C[C@@H](O)CC4)=C1)NCC5CC5

Biological Activity: LEI-401 is a first-in-class, selective, and CNS-active NAPE-PLD (N-acylphosphatidylethanolamine phospholipase D) inhibitor, with an IC50 of 27 nM. LEI-401 modulates emotional behavior in mice[1].

Cat. No. Product Name Purity Description Pricing
HY-131181 		LEI-401 99.73% LEI-401 is a first-in-class, selective, and CNS-active NAPE-PLD (N-acylphosphatidylethanolamine phospholipase D) inhibitor, with an IC50 of 27 nM. LEI-401 modulates emotional behavior in mice.
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