1542705-92-9

CB-5083 Chemical Structure
1542705-92-9

Chemical Structure

CB-5083

  • CAS No.: 1542705-92-9
  • Formula:C24H23N5O2
  • Molecular Weight:413.47

IUPAC Name: 1-(4-(benzylamino)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-2-yl)-2-methyl-1H-indole-4-carboxamide

InChIKey: RDALZZCKQFLGJP-UHFFFAOYSA-N

SMILES: O=C(C1=CC=CC2=C1C=C(C)N2C3=NC(NCC4=CC=CC=C4)=C(COCC5)C5=N3)N

Biological Activity: CB-5083 is a first-in-class, potent, selective, and orally bioavailable inhibitor of the p97 AAA ATPase/VCP. CB-5083 selectively inhibits p97 through its D2 site with the IC50 of 11 nM[1].

Cat. No. Product Name Purity Description Pricing
HY-12861 		CB-5083 99.90% CB-5083 is a first-in-class, potent, selective, and orally bioavailable inhibitor of the p97 AAA ATPase/VCP. CB-5083 selectively inhibits p97 through its D2 site with the IC50 of 11 nM.
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