1467157-21-6
Chemical Structure
Durlobactam sodium
Synonym(s): ETX2514
- CAS No.: 1467157-21-6
- Formula:C8H10N3NaO6S
- Molecular Weight:299.24
IUPAC Name: sodium (1R,2S,5R)-2-carbamoyl-3-methyl-7-oxo-1,6-diazabicyclo[3.2.1]oct-3-en-6-yl sulfate
InChIKey: WHHNOICWPZIYKI-IBTYICNHSA-M
SMILES: NC([C@H]1[N@@]2C(N([C@H](C=C1C)C2)OS(=O)(O[Na])=O)=O)=O
Biological Activity: Durlobactam sodium salt (ETX2514) is a broad-spectrum β-lactamase inhibitor with IC50s of 4, 14 and 190 nM for Class A KPC-2, Class C AmpC and Class D OXA-24, respectively. For the treatment of drug-resistant Gram-negative bacteria including Acinetobacter baumannii[1].
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Durlobactam sodium | 99.62% | Durlobactam sodium salt (ETX2514) is a broad-spectrum β-lactamase inhibitor with IC50s of 4, 14 and 190 nM for Class A KPC-2, Class C AmpC and Class D OXA-24, respectively. For the treatment of drug-resistant Gram-negative bacteria including Acinetobacter baumannii. | ||||||||||||||||||||
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Keywords