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Results for "

Couplings

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (1) ADC Antibody (2) ADC Linker (20) Adenosine Receptor (1) Adrenergic Receptor (2) Akt (1) Amino Acid Derivatives (3) Amylin Receptor (1) Amyloid-β (2) Anaplastic lymphoma kinase (ALK) (1) Angiotensin Receptor (3) Antibiotic (3) Antibody-Drug Conjugates (ADCs) (1) Apoptosis (5) Arrestin (3) Autophagy (1) Bacterial (7) Beclin1 (1) Biochemical Assay Reagents (167) Cannabinoid Receptor (1) Carboxylesterase (CES) (3) Carboxypeptidase (3) Caspase (3) Cathepsin (1) CD22 (1) Complement System (1) Cytochrome P450 (1) DNA/RNA Synthesis (1) Drug Derivative (5) Drug Intermediate (32) Drug Isomer (1) Drug-Linker Conjugates for ADC (3) E3 Ligase Ligand-Linker Conjugates (1) EGFR (2) Endogenous Metabolite (18) Environmental Pollutants (1) Exosomes (4) Fluorescent Dye (60) G2A (GPR132) (1) GCGR (1) GPR84 (1) HIF/HIF Prolyl-Hydroxylase (1) Isocitrate Dehydrogenase (IDH) (1) Isotope-Labeled Compounds (6) JNK (1) Lipase (1) Liposome (26) mAChR (1) Mas-related G-protein-coupled Receptor (MRGPR) (1) mGluR (1) Mitochondrial Metabolism (3) MMP (1) MOFs (1) Mucin (1) NF-κB (1) NO Synthase (2) Nucleoside Antimetabolite/Analog (2) Opioid Receptor (1) P2X Receptor (2) p38 MAPK (4) PD-1/PD-L1 (1) PDGFR (1) PERK (1) Phosphatase (1) Phosphodiesterase (PDE) (2) Phosphoramidites (1) PI3K (1) Pyruvate Kinase (1) RABV (1) Radionuclide-Drug Conjugates (RDCs) (3) Reactive Oxygen Species (ROS) (1) Reference Standards (10) SARS-CoV (1) Sialyltransferase (1) Target Protein Ligand-Linker Conjugates (1) TMV (1) VDAC (1) VEGFR (2)
By Research Areas:	Cancer (46) Cardiovascular Disease (10) Endocrinology (6) Infection (14) Inflammation/Immunology (29) Metabolic Disease (21) Neurological Disease (24)
Click Chemistry:	ADC Synthesis (1) Labeling and Fluorescence Imaging (1) DBCO (8) Azide (8) Tetrazine (2) Alkynes (3)
Oligonucleotides:	Pegylated Lipids (23) Nucleoside Analogs (2) Uridine (2) Phospholipids (1) Polymers (1) Other Phosphoramidite (1) Phosphoramidites (1) Cholesterol (1)

367

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

148

Biochemical Assay Reagents

Peptides

MCE Kits

Inhibitory Antibodies

Natural
Products

Isotope-Labeled Compounds

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-Y1703

HATU	Biochemical Assay Reagents	Others
HATU is a third-generation uronium salt peptide coupling reagent. HATU increases the rate of peptide coupling reactions, activates amino acids, promotes peptide bond formation in both solution-phase and solid-phase synthesis, and also facilitates peptide assembly, fragment coupling, and linear peptide cyclization. HATU can promote the N-acylation of chitosan to generate amide-linked cationic derivatives with a controllable degree of substitution. HATU is commonly used in amine acylation reactions .

HY-W018864

Tris(dibenzylideneacetonyl)bis-palladium	Biochemical Assay Reagents	Others
Tris(dibenzylideneacetonyl)bis-palladium is a catalyst that catalyzes the coupling reaction of N-methyl-2-pyrrolidinone (NMP) .

HY-Z0275

HOAT	Biochemical Assay Reagents Bacterial	Infection
HOAT is a peptide bond-forming reagent. HOAT is utilized to affect formation of peptide bonds by coupling carboxylic acids with amines. HOAt is not mutagenic in the bacterial reverse mutation test .

HY-79880

N,N'-Carbonyldiimidazole 1,1'-Carbonyldiimidazole	MOFs	Others
N,N'-Carbonyldiimidazole (1,1'-Carbonyldiimidazole) is a highly reactive carboxylating reagent that can activate hydroxyl groups to form reactive carbonyl groups. N,N'-Carbonyldiimidazole can be used as a coupling agent and a peptide synthesis reagent .

HY-21623

Dichloro[1,1'-bis(diphenylphosphino)ferrocene]palladium(II) dichloromethane adduct	Biochemical Assay Reagents	Others
Dichloro[1,1'-bis(diphenylphosphino)ferrocene]palladium(II) dichloromethane adduct is a common dichloromethane solvate of the palladium catalyst Pd(dppf)Cl₂, a phosphine ligand palladium(II) complex, which can be used as a versatile precatalyst for various cross-coupling reactions. Dichloro[1,1'-bis(diphenylphosphino)ferrocene]palladium(II) dichloromethane adduct can stabilize reaction intermediates and lower the reaction activation energy in coupling reactions, and can be used in Suzuki-Miyaura coupling reaction studies .

HY-114362

DL-alpha-Tocopherol methoxypolyethylene glycol succinate TPGS-750-M	Biochemical Assay Reagents	Others
DL-alpha-Tocopherol methoxypolyethylene glycol succinate (TPGS-750-M) is an amphiphile, acts as a surfactant. DL-alpha-Tocopherol methoxypolyethylene glycol succinate has a positive effect on Suzuki-Miyaura cross coupling. DL-alpha-Tocopherol methoxypolyethylene glycol succinate increases the styrene titer. DL-alpha-Tocopherol methoxypolyethylene glycol succinate is used in the stability test of NPYM-modified drugs in biological fluids .

HY-41456

Ethyl 2-cyano-2-(hydroxyimino)acetate	Biochemical Assay Reagents	Others
Ethyl 2-cyano-2-(hydroxyimino) acetate (Oxyma) is a peptide coupling additive. Ethyl 2-cyano-2-(hydroxyimino) acetate suppresses racemization during peptide coupling and improves the coupling efficiency of both solution-phase and solid-phase peptide synthesis .

HY-Y0912

HBTU N-HBTU	Biochemical Assay Reagents	Inflammation/Immunology
HBTU (N-HBTU) is a guanidinium-based peptide coupling reagent and immunological sensitizer. HBTU can be used in combination with bases such as DIPEA (HY-130142) to complete coupling reactions, with HOBt and TMU as by-products. HBTU is a standard reagent in automated solid-phase peptide synthesis, particularly for the Fmoc/tBu strategy, which effectively promotes coupling steps, but it is not suitable for sterically hindered amino acids or dipeptide derivatives. HBTU can induce rhinitis, dermatitis, bronchial asthma and severe allergic reactions. HBTU can be used to study the pathogenesis of allergic reactions, occupational rhinitis, allergic contact dermatitis and bronchial asthma .

HY-W011556

N,N,N',N'-Tetramethylchloroformamidinium hexafluorophosphate TCFH	Drug Isomer	Cancer
N,N,N',N'-Tetramethylchloroformamidinium hexafluorophosphate (TCFH) is a powerful coupling and derivatizing reagent for ester prodrug synthesis. N,N,N',N'-Tetramethylchloroformamidinium hexafluorophosphate can be used for antitumor drugs before medicine research .

HY-D0177

(Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate	Biochemical Assay Reagents	Others
(Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate (Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate) is a peptide coupling reagent and BOP analog. (Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate promotes the reaction of amino and carboxyl groups to form peptide bonds. (Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate can be used in the synthesis of peptide compounds .

HY-D2171A

AF488 DBCO ditriethylamine 1 Publications Verification	Fluorescent Dye	Others
AF488 DBCO ditriethylamineis a fluorescent dye and also a click chemistry reagent that can label azide-containing biomolecules. AF488 DBCO ditriethylaminemediates the coupling reaction with azide-modified 2'-OMe RNA oligonucleotides. DBCO is a bioorthogonal partner of azides and enables covalent coupling without copper (Ex/Em = 470/520 nm) .

HY-151817

5-Azidomethyl-uridine	Biochemical Assay Reagents	Others
5-Azidomethyl-uridine is a click chemistry reagent containing an azide group. The azide function is widely used for coupling to alkyne-containing fragments via the renowned Click reaction.

HY-W090940

H-Gly-Gly-Phe-OH	ADC Linker	Cancer
H-Gly-Gly-Phe-OH is a tripeptide linker that may be used in the creation of antibody drug conjugates (ADCs). The N-terminal of the glycine tripeptide is free to perform a variety of reactions such as couplings with carboxylic acids or NHS esters.

HY-168940B

NH2-PEG2000-COOH	Drug Intermediate	Cancer
NH2-PEG2000-COOH is a heterofunctional polyethylene glycol with one amino terminal group and one carboxyl terminal group. NH2-PEG2000-COOH reacts with N-succinimidyl-6-maleimidohexanoate to introduce a maleimide terminal group, followed by conjugation with thiolated RGD peptide via a thiol-maleimide coupling reaction to synthesize RGD-PEG-COOH. NH2-PEG2000-COOH can be used in cancer research .

HY-15933

TOPS 1 Publications Verification	Biochemical Assay Reagents	Others Metabolic Disease
TOPS is a chromogenic substrate. TOPS undergoes an oxidative coupling reaction with 4-aminoantipyrine in the presence of H₂O₂ and nanocrystalline cobalt selenide. TOPS is used in studies related to uric acid detection .

HY-D1916

ATTO 594	Fluorescent Dye Mucin	Others
ATTO 594 is a Fluorescent dye (excitation/emission = 603/626 nm). ATTO 594 is covalently conjugated to Mucin via carbodiimide coupling .

HY-Y0747

Iodobenzene 1-Iodobenzene	Biochemical Assay Reagents	Others
Iodobenzene can undergo Ullmann coupling reaction on copper catalyst to generate biphenyl. Iodobenzene can undergo Suzuki reaction with phenylboronic acid to generate biphenyl .

HY-32951

2-Fluoropyridine-4-boronic acid	Drug Intermediate	Others
2-Fluoropyridine-4-boronic acid is a coupling reagent and chemical intermediate. 2-Fluoropyridine-4-boronic acid facilitates the synthesis of Rho kinase (ROCK) inhibitor Compound 37 .

HY-107783

Sulfo-GMBS	Biochemical Assay Reagents	Others
Sulfo-GMBS is a crosslinker widely used in chemical modification and coupling reactions of proteins and peptides. Among amine-thiol crosslinkers, Sulfo-GMBS generates the largest number of crosslinks and covers most of the crosslinks identified by AMAS and GMBS .

HY-W011412

TSTU	Biochemical Assay Reagents	Others
TSTU is used as a coupling reagent in peptide chemistry. TSTU can convert carboxylic acids into the corresponding N-hydroxysuccinimidyl (NHS) esters. TSTU can be applied to the attachment of labels to peptides, proteins, etc .

HY-D2171

AF488 DBCO	Fluorescent Dye	Others
AF488 DBCO is a fluorescent dye and also a click chemistry reagent that can label azide-containing biomolecules. AF488 DBCO mediates the coupling reaction with azide-modified 2'-OMe RNA oligonucleotides. DBCO is a bioorthogonal partner of azides and enables covalent coupling without copper (Ex/Em = 470/520 nm) .

HY-W010986

Fmoc-N-Me-Phe-OH	Drug Intermediate	Others
Fmoc-N-Me-Phe-OH is an N-methylated amino acid that can be used for the synthesis of some active compounds .

HY-W036410

Aminopropyltrimethoxysilane 1 Publications Verification 3-Aminopropyltrimethoxysilane	Environmental Pollutants Biochemical Assay Reagents	Others
Aminopropyltrimethoxysilane (APTMS) is a silane coupling agent. Aminopropyltrimethoxysilane couples with Tosylcellulose. Aminopropyltrimethoxysilane improves the thermal stability of the material. Aminopropyltrimethoxysilane can be used in the preparation of GNBP substrates .

HY-160291

Trivalent GalNAc-DBCO	Biochemical Assay Reagents	Others
Trivalent GalNAc-DBCO can be used for oligonucleotide coupling .

HY-W003601

2-Bromo-4-fluoropyridine	Biochemical Assay Reagents	Others
2-Bromo-4-fluoropyridine is a synthetic halogenated heterocyclic organic compound and a key intermediate in the pharmaceutical and agrochemical industries. 2-Bromo-4-fluoropyridine can be used to synthesize bioactive molecules through cross-coupling reactions, such as Suzuki coupling or Buchwald-Hartwig amination.

HY-159734

TPP-resveratrol	Apoptosis	Cancer
TPP-resveratrol is a conjugate of Resveratrol (HY-16561) and triphenylphosphine (TPP) with anticancer activity. TPP-resveratrol increases the potency of Resveratrol through mitochondrial-targeted delivery and induces mitochondria-mediated apoptosis .

HY-D0798

Catechol violet	Fluorescent Dye	Others
Catechol violet is an efficient and versatile ligand for Cu(I)-catalyzed C-S coupling reactions. Catechol violet is also a complexometric indicator dye .

HY-123067

NBD-Fructose	Fluorescent Dye	Metabolic Disease
NBD-Fructose is a fluorescent derivative of Fructose (HY-N0395) that is formed by coupling NBD-chloride with the amine group of amino fructose (EX/Em=472/538 nm) .

HY-46225

DEX-maleimide	Drug Intermediate	Inflammation/Immunology
DEX-maleimide is a coupling agent that can be used to synthesize conjugates containing single-domain antibodies (VHH) conjugated with antigens and anti-inflammatory agents. DEX-maleimide can be used for research on autoimmune diseases .

HY-13443B

Exendin-4-Lys-azide TFA	GCGR	Cardiovascular Disease Metabolic Disease Cancer
Exendin-4-Lys-azide TFA (Compound Ex40) is an azide derivative of Exendin-4-Lys-azide, Exendin-4, which can be used for coupling/click chemistry .

HY-D2448

Cy3-PEG-Thiol	Fluorescent Dye	Cancer
Cy3-PEG-Thiol (Cy3-PEG-SH) is a near infrared fluorescent labeling reagent that combines Cy3 fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) polyethylene glycol derivatives, and is suitable for molecular coupling. Cy3-PEG-Thiol is absorbed at 550nm and has high solubility and end-group substitution rate .

HY-75637

3-Amino-5-methylpyrazole	Drug Intermediate	Others
5-Methyl-1H-pyrazol-3-amine is a pyrazole heterocyclic compound and can be used as a key intermediate for the synthesis of pyrazolylamide derivatives.

HY-172164B

FITC-lysine-dextran (MW 70kDa)	Fluorescent Dye	Others
FITC-lysine-dextran, 70kDa is a dextran with lysine coupling with a fluorescent group FITC (HY-66019). Lysine-dextran exhibits higher Glu-plasminogen binding ability than dextran alone .

HY-P11501

AAKLVFF	Amyloid-β Biochemical Assay Reagents	Neurological Disease
AAKLVFF is an oligopeptide capable of self-assembling into nanotubes. AAKLVFF can be derived from the core section of β-amyloid. AAKLVFF becomes the first methanol compatible LC alignment medium for residual dipolar coupling measurement .

HY-151637

Fmoc-N-propargyl-MPBA	Amino Acid Derivatives	Others
Fmoc-N-propargyl-MPBA is a propargyl-substituted MPBA linker derived from 4-hydroxy-3-methoxybenzaldehyde. Fmoc-N-propargyl-MPBA can be elongated using standard Fmoc-based solid phase chemistry and linked to supports by standard coupling procedures . Fmoc-N-propargyl-MPBA is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-101218

N-Biotinyl-6-aminohexanoic acid N-(+)-Biotinyl-6-aminohexanoic acid	Sialyltransferase	Others
N-Biotinyl-6-aminohexanoic acid (N-(+)-Biotinyl-6-aminohexanoic acid) can be used to perform biotinylation .

HY-161541

Estradiol/BSA 1 Publications Verification	Biochemical Assay Reagents	Inflammation/Immunology
Estradiol/BSA is the antigen-adjuvant conjugate formed by the coupling of Estradiol (HY-B0141) with Bovine Serum Albumin (BSA). By coupling the antigen with a protein adjuvant, the production of antigen-specific antibodies in vaccine models can be enhanced. The conjugate does not affect protein folding or disrupt major epitopes, and it can enhance cross-presentation and the generation of antigen-specific T cells.

HY-W004650A

TETA tetraTFA	Biochemical Assay Reagents	Others
TETA (tetraTFA) is an effective selective chelating agent for copper (II). TETA (tetraTFA) can be used for drug coupling .

HY-161526

T3/KLH	Biochemical Assay Reagents	Inflammation/Immunology
T3/KLH is an antigen-adjuvant conjugate formed by the coupling of T3 (thyroid hormone) with keyhole limpet hemocyanin (KLH). By coupling the antigen with the protein adjuvant, the production of antigen-specific antibodies in vaccine models can be enhanced. The conjugate does not affect protein folding or disrupt major epitopes, and it can enhance cross-presentation and the generation of antigen-specific T cells.

HY-W013598

Sodium benzenesulfinate	Biochemical Assay Reagents	Others
Sodium benzenesulfinate is a reagent used in organic synthesis to create other compounds, such as sulfones. Sodium benzenesulfinate undergoes rhodium-catalyzed desulfinative coupling with aldehydes to yield ketones .

HY-W441014B

DSPE-PEG20000-NHS ammonium	Biochemical Assay Reagents	Others
DSPE-PEG20000-NHS ammonium is one of the most commonly used reactive phospholipids for coupling antibodies, proteins, peptides or other substrates to the surface of liposomes and other lipid PEG nanoparticles .

HY-P3430

JM3A	Biochemical Assay Reagents	Cancer
JM3A is a highly specific peptoid reagent that targets newly appears cell surface vimentin (CSV) on tumor-transformed early lung cancer cells. JM3A can detect and stain CSV by coupling with fluorophores .

HY-Y0747S

Iodobenzene-d5 1-Iodobenzene-d₅	Isotope-Labeled Compounds	Others
Iodobenzene-d₅ is the deuterium labeled 1-Iodobenzene. Iodobenzene can undergo Ullmann coupling reaction on copper catalyst to generate biphenyl. Iodobenzene can undergo Suzuki reaction with phenylboronic acid to generate biphenyl .

HY-W004698

(2-Methoxypyrimidin-5-yl)boronic acid	Drug Intermediate	Others
(2-Methoxypyrimidin-5-yl)boronic acid is a drug intermediate that can serve as a key reactant in the Suzuki-Miyaura coupling reaction, and is used for the synthesis of isoquinoline ketone derivatives with anti-tumor activity .

HY-D2510

Cy3-PEG2000-SH	Fluorescent Dye	Cancer
Cy3-PEG2000-SH (Cy3-PEG-Thiol) is a near infrared fluorescent labeling reagent that combines Cy3 fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) polyethylene glycol derivatives, and is suitable for molecular coupling. Cy3-PEG2000-SH is absorbed at 550nm and has high solubility and end-group substitution rate .

HY-130908

11-Maleimidoundecanoic acid	Biochemical Assay Reagents	Cancer
11-Maleimidoundecanoic acid is a maleimide-containing hydrophobic core former. 11-Maleimidoundecanoic acid forms a hydrophobic core via maleimide-thiol coupling with cysteine residues on polypeptides, enabling stable loading and controllable release of Doxorubicin (HY-15142A). 11-Maleimidoundecanoic acid can be used for the research of breast cancer .

HY-151686

Bz-(Me)Tz-NHS	Biochemical Assay Reagents	Others
Bz-(Me)Tz-NHS is a methyltetrazine carboxylic acid NHS ester that enables conjugation of the tetrazine moiety to the 5' end of oligonucleotides via amide coupling reaction, and it is used in oligonucleotide template-mediated fluorescent bioorthogonal cycloaddition reactions. Bz-(Me) Tz-NHS is applicable to click chemistry-related studies .

HY-W688571

T-02	Biochemical Assay Reagents	Others
T-02 is an isocyanate silane coupling agent .

HY-133883

Cyanine7.5 amine	Fluorescent Dye	Others
Cyanine7.5 amine is a near-infrared Cy7.5-based dye and also a substrate for amide bond coupling (Ex/Em = 788 nm/808 nm). Cyanine7.5 amine contains a free amino group and can be used for coupling with activated carboxylic acid derivatives .

HY-32928

4-Cyanobenzeneboronic acid	Biochemical Assay Reagents	Others
4-Cyanobenzeneboronic acid is a Boronic acid derivative. 4-Cyanobenzeneboronic acid can be used in Suzuki-Miyaura cross-coupling reactions .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W087952

(R)-(-)-2-Butanol	Natural Products Microorganisms Classification of Application Fields Metabolic Disease Disease Research Fields Source Classification	Drug Intermediate
(R)-(-)-2-Butanol is the isomer of 2-Butanol, which is found in the females of the white grub beetle, Dasylepida ishigakiensis, to attract males. (R)-(-)-2-Butanol is an intermediate of pharmaceutical synthesis by coupling .

HY-148978

18:0,18:1 PS sodium	Structural Classification Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Lipid Source Classification	Exosomes Endogenous Metabolite Liposome
18:0,18:1 PS sodium is the dominant phosphatidylserine subtype in cells, exosomes and HIV particles. It is abundant in the brain and is essential for maintaining membrane structure, lipid raft organization and intracellular trafficking. 18:0,18:1 PS sodium mediates interleaflet membrane coupling through cholesterol-dependent interactions with very long-chain sphingolipids, and can induce the clustering of glycosylphosphatidylinositol-anchored proteins. In addition, clusters formed by the binding of 18:0,18:1 PS sodium to cholesterol not only facilitate the proper distribution of cholesterol in lipid bilayers, but also effectively protect cholesterol from oxidative damage .

HY-N1356A

(R)-Reticuline	Structural Classification Alkaloids Plants Lauraceae Isoquinoline Alkaloids Lindera aggregata (Sims) Kosterm. Source Classification	Cytochrome P450
(R)-Reticuline is a key intermediate and precursor in the biosynthetic pathway of morphinan alkaloids. (R)-Reticuline plays a central role in the metabolism of opium poppy (Papaver somniferum). (R)-Reticuline can either undergo O-methylation catalyzed by PSOMT1, or be converted to (+)-Salutaridine via regioselective and stereoselective oxidative coupling under the action of salutaridine synthase (CYP719B1). (R)-Reticuline serves as a direct precursor for the synthesis of important alkaloids such as morphine, codeine and thebaine .

HY-N10511

GM1a Ganglioside oligosaccharide	Natural Products Polysaccharides Classification of Application Fields Endogenous metabolite Inflammation/Immunology Disease Research Fields Saccharides	Others
GM1a Ganglioside oligosaccharide is a semisynthetic form of ganglioside GM1. Ganglioside GM1 is the natural receptor for cholera toxin and plays an important role not only in general growth regulation but also in the coupling of hormone-induced responses .

HY-120286

K-13	Natural Products Microorganisms Source Classification	Drug Intermediate
K-13 is a cyclic peptide compound synthesized by a specific organozinc reagent. Its synthesis process involves intermolecular and intramolecular Negishi cross-coupling reactions and is one of the shortest routes reported for the synthesis of such cyclic peptides.

HY-148978R

18:0,18:1 PS sodium (Standard)	Structural Classification Natural Products Endogenous metabolite Source Classification	Reference Standards Exosomes Endogenous Metabolite Liposome
Resorantel (Standard) is the analytical standard of Resorantel. This product is intended for research and analytical applications. 18:0,18:1 PS sodium is the dominant phosphatidylserine subtype in cells, exosomes and HIV particles. It is abundant in the brain and is essential for maintaining membrane structure, lipid raft organization and intracellular trafficking. 18:0,18:1 PS sodium mediates interleaflet membrane coupling through cholesterol-dependent interactions with very long-chain sphingolipids, and can induce the clustering of glycosylphosphatidylinositol-anchored proteins. In addition, clusters formed by the binding of 18:0,18:1 PS sodium to cholesterol not only facilitate the proper distribution of cholesterol in lipid bilayers, but also effectively protect cholesterol from oxidative damage .

HY-W653461

4,5-Dimethyloctane	Structural Classification Natural Products Rosaceae Plants Rosa rugosa Thunb. Source Classification	Biochemical Assay Reagents
4,5-Dimethyloctane is a product from n-pentane/iso-butane coupling .

HY-N15196

Andrographolide-lipoic acid	Natural Products Acanthaceae Simsia foetida (Cav.) S.F.Blake Plants Source Classification	NF-κB
Andrographolide-lipoic acid is an Andrographolide (HY-N0191) analogue, which is formed by the coupling of Andrographolide and Lipoic acid (HY-18733). Andrographolide-lipoic acid inhibits NF-κB and has anti-diabetic and β-cell protective activities .

HY-N18366

Dulcoside C	Structural Classification Terpenoids Cassia Diterpenoids Plants Compositae Source Classification	Drug Derivative
Dulcoside C is a rhamnose-containing steviol glycoside found in Stevia rebaudiana leaves.Dulcoside C exhibits significantly lower sweetness compared to Rebaudioside A (HY-N0466) .

HY-N18253

Dehydroaromadendrane	Structural Classification Terpenoids Encephalartos villosus Lem. Sesquiterpenes Plants Zamiaceae Source Classification	Drug Derivative
Dehydroaromadendrane is an aromadendrane derivative sesquiterpene .

Cat. No.	Product Name	Chemical Structure

HY-W744953

Carbimazole-d3

Carbimazole-d₃ is deuterium labeled Carbimazole. Carbimazole is an orally active antithyroid agent which rapidly converts to Methimazole after absorption and prevents thyroid peroxidase enzyme from iodinating and coupling the tyrosine residues on thyroglobulin, hence reducing the production of thyroxine. Carbimazole also displays anti-inflammatory and neuronal-protective activities, suggesting its application for hyperthyroidism and neurological research .

HY-B0558S

Carbimazole-d5

Carbimazole-d₅ is deuterium labeled Carbimazole. Carbimazole is an orally active antithyroid agent which rapidly converts to Methimazole after absorption and prevents thyroid peroxidase enzyme from iodinating and coupling the tyrosine residues on thyroglobulin, hence reducing the production of thyroxine. Carbimazole also displays anti-inflammatory and neuronal-protective activities, suggesting its application for hyperthyroidism and neurological research .

HY-W701476

Ethyl phenylglyoxylate-d5

Ethyl phenylglyoxylate-d₅ (Ethyl benzoylformate-d₅; Phenylglyoxylic acid ethyl ester-d₅) is the deuterium labeled Ethyl phenylglyoxylate (HY-W016618). Ethyl phenylglyoxylate (Ethyl benzoylformate), the ethyl ester of phenylglyoxylic acid, is used as a synthetic reagent. Ethyl phenylglyoxylate is also a poor substrate but a potent inhibitor of chicken liver carboxylesterase. Additionally, Ethyl phenylglyoxylate exhibits photoreactivity, where its excited triplet carbonyl can initiate intermolecular hydrogen abstraction, radical coupling and cross-linking reactions .

HY-Y0747S1

Iodobenzene-d2
Iodobenzene-d₂ is the deuterium labeled 1-Iodobenzene. Iodobenzene can undergo Ullmann coupling reaction on copper catalyst to generate biphenyl. Iodobenzene can undergo Suzuki reaction with phenylboronic acid to generate biphenyl .

HY-145547S

1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine-d27

1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine-d₂₇ (14:0 Lyso PE-d₂₇) is the deuterium labeled 1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine. 1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine (14:0 Lyso PE) is a lysophospholipid with a phosphoethanolamine head and a myristoyl tail. The free amine group can conjugate with NHS active ester or coupled with carboxylic acid in the presence of a coupling agent. It also induces transient increases in intracellular calcium in PC12 cells .

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