71 Results for "

DMF D6

" in MedChemExpress (MCE) Product Catalog:
Products (71)

71 Results for "DMF D6" in MCE Product Catalog:

64
64 Publications Verification
Cat. No.: HY-17363
CAS No.: 624-49-7
Dimethyl fumarate (DMF) is an orally active and brain-penetrant Nrf2 activator and induces upregulation of antioxidant gene expression. Dimethyl fumarate induces necroptosis in colon cancer cells through GSH depletion/ROS increase/MAPKs activation pathway, and also induces cell autophagy. Dimethyl fumarate can be used for multiple sclerosis research .
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45
45 Cited Publications
Cat. No.: HY-D0819
CAS No.: 146368-14-1
Synonyms: Cy5 NHS Ester; Sulfo-Cyanine5 Succinimidyl Ester
Cy5-SE (Cy5 NHS Ester) is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. This dye requires small amount of organic co-solvent (such as DMF or DMSO) to be used in labeling reaction. This reagent is ideal for very cost-efficient labeling of soluble proteins, as well as all kinds of peptides and oligonucleotides. This reagent also works well in organic solvents for small molecule labeling. Excitation (nm):649, Emission (nm): 670.
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7
7 Cited Publications
Cat. No.: HY-103252
CAS No.: 2756-87-8
Purity:  99.95%
Monomethyl fumarate, an active metabolite of Dimethyl fumarate (DMF), is a potent GPR109A agonist. Monomethyl fumarate has the potential for multiple neuroprotective pathways and other models of retinal disease .
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5
5 Cited Publications
Cat. No.: HY-100375
CAS No.: 1577222-14-0
Purity:  99.90%
Synonyms: ALKS 8700; BIIB098
Target:  

Keap1-Nrf2

Research Areas:  

Inflammation/Immunology

Diroximel fumarate (ALKS 8700) is an orally-active and well-tolerated monomethyl fumarate (MMF) proagent in a controlled-release formulation. Diroximel fumarate is considered as active equivalent to its active metabolite dimethyl fumarate (DMF). Diroximel fumarate has a favorable safety and efficacy profile, has the potential for the study of multiple sclerosis (MS). Diroximel fumarate is a Nrf2 activator that alleviate MGO-induced pain hypersensitivity .
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4
4 Cited Publications
Cat. No.: HY-W015883
CAS No.: 110-17-8
Fumaric acid is an unsaturated dicarbonic acid, an intermediate product of the citric acid cycle that provides intracellular energy in the form of ATP. Fumaric acid exerts anti-inflammatory effects by inhibiting the NF-κB signaling pathway dependent on p38 MAPK. Fumaric acid can be used in the study of pregnancy-induced hypertension .
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4
4 Cited Publications
Cat. No.: HY-W015883A
CAS No.: 17013-01-3
Fumaric acid disodium is an unsaturated dicarbonic acid, an intermediate product of the citric acid cycle that provides intracellular energy in the form of ATP. Fumaric acid disodium exerts anti-inflammatory effects by inhibiting the NF-κB signaling pathway dependent on p38 MAPK. Fumaric acid disodium can be used in the study of pregnancy-induced hypertension .
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1
1 Cited Publications
Cat. No.: HY-Y0543
CAS No.: 620-02-0
5-Methylfurfural is a chemical that can be utilized as food additive, intermediate in the production of agrochemicals, and precursor of certain anti-cancer natural products. 5-Methylfurfural is formed during the photoexposition of ranitidine hydrochloride. 5-Methylfurfural is an organic compound. 5-Methylfurfural has a strong tendency to be further hydrogenated to 2,5-dimethylfuran (DMF). 5-Methylfurfural can predominantly evoke skin inflammation and barrier disintegration. 5-Methylfurfural degrades native DNA through the formation of single-strand breaks .
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1
1 Cited Publications
Cat. No.: HY-103252S
CAS No.: 1616345-41-5
Purity:  98.24%
Monomethyl fumarate-d3 is a deuterium labeled Monomethyl fumarate (HY-103252). Monomethyl fumarate, an active metabolite of Dimethyl fumarate (DMF) (HY-17363), is a potent GPR109A agonist. Monomethyl fumarate has the potential for multiple neuroprotective pathways and other models of retinal disease .
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Cat. No.: HY-DY2002
CAS No.: 7240-90-6
X-GAL (BCIG) (solution) is a widely used chromogenic β-galactosidase substrate. X-GAL is a colorless compound until cleaved by β-galactosidase, at which point X-GAL turns to an insoluble and detectable blue compound, making X-GAL particularly useful in techniques such as blue-white screening for cloning in bacteria. X-GAL can also be used for detection of β-galactosidase activity .
Solvent and Concentration: DMF: 20 mg/mL
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Cat. No.: HY-138585
CAS No.: 330628-04-1
Purity:  99.71%
DMT-dG(dmf) Phosphoramidite is a phosphinamide monomer that can be used in the preparation of oligonucleotides
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Cat. No.: HY-Y1078
CAS No.: 4637-24-5
Synonyms: N-Dimethoxymethyl-N,N-dimethylamine
Research Areas:  

Others

DMF-DMA (N-Dimethoxymethyl-N,N-dimethylamine) is a reagent with both condensation and alkylation functions. DMF-DMA can undergo condensation reactions with active methylene groups or amino groups to generate enamine and imino derivatives, and can also act as an alkylating agent to methylate nitrogen and oxygen atoms in heterocyclic structures. DMF-DMA is widely used in the synthesis of enaminones and dimethylamino imine intermediates, as well as in the construction of heterocyclic backbones such as pyridine, pyrimidine and pyrazole. DMF-DMA can also serve as a polar aprotic co-solvent; although DMF-DMA cannot dissolve cellulose alone, it can form an efficient cellulose dissolution system with diallylimidazolium methoxyacetate .
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Cat. No.: HY-W015883S4
CAS No.: 194160-45-7
Fumaric acid-d4 is the d4-labeled Fumaric acid (HY-W015883). Fumaric acid is an unsaturated dicarbonic acid, an intermediate product of the citric acid cycle that provides intracellular energy in the form of ATP. Fumaric acid exerts anti-inflammatory effects by inhibiting the NF-κB signaling pathway dependent on p38 MAPK. Fumaric acid can be used in the study of pregnancy-induced hypertension .
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Cat. No.: HY-W015883S
CAS No.: 201595-62-2
Fumaric acid- 13C4 is the 13C-labeled Fumaric acid (HY-W015883). Fumaric acid is an unsaturated dicarbonic acid, an intermediate product of the citric acid cycle that provides intracellular energy in the form of ATP. Fumaric acid exerts anti-inflammatory effects by inhibiting the NF-κB signaling pathway dependent on p38 MAPK. Fumaric acid can be used in the study of pregnancy-induced hypertension .
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Cat. No.: HY-W402064
CAS No.: 16265-37-5
Research Areas:  

Others

N-Acetyladenosine is an adenosine analog and an adenosine N 6-acylated derivative. N-Acetyladenosine can be produced via the heterolytic reaction between adenosine and diacetyl peroxide .
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Cat. No.: HY-W010922
CAS No.: 162558-25-0
Research Areas:  

Others

Fmoc-Dap (Boc)-OH is an amino acid derivative bearing the Fmoc protecting group. Fmoc-Dap (Boc)-OH supports Fmoc-based solid-phase peptide synthesis for the preparation of bicyclic tachykinin NK2 receptor antagonists .
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Cat. No.: HY-W003486
CAS No.: 57489-77-7
Research Areas:  

Neurological Disease Cancer

5,7-Dichloropyrazolo[1,5-a]pyrimidine is a PDE10A inhibitor with a Ki of 24 μM. 5,7-Dichloropyrazolo[1,5-a]pyrimidine serves as a key intermediate in the synthesis of 5,7-disubstituted pyrazolo[1,5-a]pyrimidine derivatives (HIV-1 non-nucleoside reverse transcriptase inhibitors). 5,7-Dichloropyrazolo[1,5-a]pyrimidine can be used for the research of schizophrenia .
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Cat. No.: HY-W015883S1
CAS No.: 96503-56-9
Fumaric acid- 13C2 is the 13C-labeled Fumaric acid (HY-W015883). Fumaric acid is an unsaturated dicarbonic acid, an intermediate product of the citric acid cycle that provides intracellular energy in the form of ATP. Fumaric acid exerts anti-inflammatory effects by inhibiting the NF-κB signaling pathway dependent on p38 MAPK. Fumaric acid can be used in the study of pregnancy-induced hypertension .
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Cat. No.: HY-W015883S3
CAS No.: 24461-32-3
Fumaric acid-d2 is the d2-labeled Fumaric acid (HY-W015883). Fumaric acid is an unsaturated dicarbonic acid, an intermediate product of the citric acid cycle that provides intracellular energy in the form of ATP. Fumaric acid exerts anti-inflammatory effects by inhibiting the NF-κB signaling pathway dependent on p38 MAPK. Fumaric acid can be used in the study of pregnancy-induced hypertension .
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Cat. No.: HY-17363S1
CAS No.: 23057-98-9
Dimethyl fumarate-d2 is the deuterium labeled Dimethyl fumarate . Dimethyl fumarate (DMF) is an orally active and brain-penetrant Nrf2 activator and induces upregulation of antioxidant gene expression. Dimethyl fumarate induces necroptosis in colon cancer cells through GSH depletion/ROS increase/MAPKs activation pathway, and also induces cell autophagy. Dimethyl fumarate can be used for multiple sclerosis research .
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Cat. No.: HY-177360
CAS No.: 3067915-73-2
Synonyms: RNA splicing modulator-4
Target:  

DNA/RNA Synthesis

Ruxuplam (RNA splicing modulator-4) is an RNA splicing modulator. Ruxuplam controls the inclusion or exclusion of specific exons in precursor mRNA (pre-mRNA) by regulating alternative splicing events, thereby altering the coding sequence and function of mature mRNA. Ruxuplam shows promise for research into neurodegenerative diseases (such as Huntington's disease) and cancers .
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