24461-32-3
24461-32-3
Chemical Structure
Fumaric acid-d2
- CAS No.: 24461-32-3
- Formula:C4H2D2O4
- Molecular Weight:118.08
InChIKey: VZCYOOQTPOCHFL-FBBQFRKLSA-N
SMILES: OC(/C([2H])=C([2H])/C(O)=O)=O
Biological Activity: Fumaric acid-d2 is the deuterium labeled Fumaric acid[1]. Fumaric acid, associated with fumarase deficiency, is identified as an oncometabolite or an endogenous, cancer causing metabolite[2].
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Fumaric acid-d2 | 99.50% | Fumaric acid-d2 is the deuterium labeled Fumaric acid. Fumaric acid, associated with fumarase deficiency, is identified as an oncometabolite or an endogenous, cancer causing metabolite. | ||||||||||||||||||||
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Fumaric acid (Standard) | 99.93% | Fumaric acid (Standard) is the analytical standard of Fumaric acid. This product is intended for research and analytical applications. Fumaric acid is an unsaturated dicarbonic acid, an intermediate product of the citric acid cycle that provides intracellular energy in the form of ATP. Fumaric acid exerts anti-inflammatory effects by inhibiting the NF-κB signaling pathway dependent on p38 MAPK. Fumaric acid can be used in the study of pregnancy-induced hypertension. | ||||||||||||||||||||
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Fumaric acid-13C2 | 99.9% | Fumaric acid-13C2 is the 13C-labeled Fumaric acid (HY-W015883). Fumaric acid is an unsaturated dicarbonic acid, an intermediate product of the citric acid cycle that provides intracellular energy in the form of ATP. Fumaric acid exerts anti-inflammatory effects by inhibiting the NF-κB signaling pathway dependent on p38 MAPK. Fumaric acid can be used in the study of pregnancy-induced hypertension. | ||||||||||||||||||||
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Fumaric acid-13C2,d2 | 98.00% | Fumaric acid-13C2,d2 is the deuterium and 13C labeled Fumaric acid. Fumaric acid, associated with fumarase deficiency, is identified as an oncometabolite or an endogenous, cancer causing metabolite. | ||||||||||||||||||||
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Fumaric acid-d4 | 98% | Fumaric acid-d4 is the deuterium labeled Fumaric acid. Fumaric acid, associated with fumarase deficiency, is identified as an oncometabolite or an endogenous, cancer causing metabolite. | ||||||||||||||||||||
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Fumaric acid-13C4 | 98.0% | Fumaric acid-13C4 is the 13C-labeled Fumaric acid. Fumaric acid, associated with fumarase deficiency, is identified as an oncometabolite or an endogenous, cancer causing metabolite. | ||||||||||||||||||||
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Fumaric acid2,3-13C2 disodium | 99% | Fumaric acid2,3-13C2 (disodium) is the deuterium labeled Fumaric acid disodium. | ||||||||||||||||||||
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Fumaric acid | 99.91% | Fumaric acid is an unsaturated dicarbonic acid, an intermediate product of the citric acid cycle that provides intracellular energy in the form of ATP. Fumaric acid exerts anti-inflammatory effects by inhibiting the NF-κB signaling pathway dependent on p38 MAPK. Fumaric acid can be used in the study of pregnancy-induced hypertension. | ||||||||||||||||||||
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References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
- [2]. Whelan DT, et al. Fumaric aciduria: a new organic aciduria, associated with mental retardation and speech impairment. Clin Chim Acta. 1983 Aug 31;132(3):301-8. [Content Brief]
