2. Maleic Acid

Maleic Acid is a Glutamate Decarboxylase (GAD) inhibitor of E. coli and L. monocytogenes.

For research use only. We do not sell to patients.

Maleic Acid Chemical Structure

Maleic Acid Chemical Structure

CAS No. : 110-16-7

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in Water
ready for reconstitution
 USD 33 In-stock
Solution
10 mM * 1 mL in Water USD 33 In-stock
Solid
500 mg USD 30 In-stock
5 g USD 40 In-stock
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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Maleic Acid:

Maleic Acid Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Maleic Acid

  • Biological Activity

  • Purity & Documentation

  • Customer Review

Description

Maleic Acid is a Glutamate Decarboxylase (GAD) inhibitor of E. coli and L. monocytogenes.

IC50 & Target

GAD[1][2].
In Vitro

The MICs of WT 10403S for the acids (e.g., Maleic Acid) are 34 mM, 25 mM, 31 mM and 30 mM which correspond to pH values prior to growth of 4.84, 5.14, 5.32 and 5.02 respectively. Of all compounds tested, Maleic Acid is the least inhibitory despite acting at a lower pH (4.84). The most acid resistant (10403S) and the weakest (EGD-e) strain are challenged with 8.6 mM and 4.3 mM of each organic acid at pH 3 and 3.3 respectively. On both strains, Maleic Acid is the most bactericidal[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Maleic Acid Related Antibodies
Clinical Trial
Molecular Weight

116.07

Formula

C4H4O4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(O)/C=C\C(O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (861.55 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 8.6155 mL 43.0775 mL 86.1549 mL
5 mM 1.7231 mL 8.6155 mL 17.2310 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 100 mg/mL (861.55 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 99.86%

COA (247 KB) HNMR (177 KB) RP-HPLC (187 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 8.6155 mL 43.0775 mL 86.1549 mL 215.3873 mL
5 mM 1.7231 mL 8.6155 mL 17.2310 mL 43.0775 mL
10 mM 0.8615 mL 4.3077 mL 8.6155 mL 21.5387 mL
15 mM 0.5744 mL 2.8718 mL 5.7437 mL 14.3592 mL
20 mM 0.4308 mL 2.1539 mL 4.3077 mL 10.7694 mL
25 mM 0.3446 mL 1.7231 mL 3.4462 mL 8.6155 mL
30 mM 0.2872 mL 1.4359 mL 2.8718 mL 7.1796 mL
40 mM 0.2154 mL 1.0769 mL 2.1539 mL 5.3847 mL
50 mM 0.1723 mL 0.8615 mL 1.7231 mL 4.3077 mL
60 mM 0.1436 mL 0.7180 mL 1.4359 mL 3.5898 mL
80 mM 0.1077 mL 0.5385 mL 1.0769 mL 2.6923 mL
100 mM 0.0862 mL 0.4308 mL 0.8615 mL 2.1539 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Maleic Acid110-16-7Inhibitorinhibitorinhibit

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