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Diroximel fumarate (Synonyms: ALKS 8700; BIIB098)

Cat. No.: HY-100375 Purity: 99.90%
Handling Instructions

Fumarate de diroximel (ALKS 8700) est un promédicament oralement actif de monométhyl fumarate (MMF)et bien toléré dans une formulation à libération contrôlée. Fumarate de diroximel est considéré comme un équivalent actif de son métabolite actif, fumarate de diméthyle (DMF). Fumarate de diroximel a un profil d'innocuité et d'efficacité favorable, a le potentiel pour l'étude de la sclérose en plaques (SEP).

Diroximel fumarate (ALKS 8700) is an orally-active and well-tolerated monomethyl fumarate (MMF) prodrug in a controlled-release formulation. Diroximel fumarate is considered as active equivalent to its active metabolite dimethyl fumarate (DMF). Diroximel fumarate has a favorable safety and efficacy profile, has the potential for the study of multiple sclerosis (MS).

For research use only. We do not sell to patients.

Diroximel fumarate Chemical Structure

Diroximel fumarate Chemical Structure

CAS No. : 1577222-14-0

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 165 In-stock
Estimated Time of Arrival: December 31
5 mg USD 150 In-stock
Estimated Time of Arrival: December 31
10 mg USD 210 In-stock
Estimated Time of Arrival: December 31
50 mg USD 550 In-stock
Estimated Time of Arrival: December 31
100 mg USD 750 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Description

Diroximel fumarate (ALKS 8700) is an orally-active and well-tolerated monomethyl fumarate (MMF) prodrug in a controlled-release formulation. Diroximel fumarate is considered as active equivalent to its active metabolite dimethyl fumarate (DMF). Diroximel fumarate has a favorable safety and efficacy profile, has the potential for the study of multiple sclerosis (MS)[1].

Clinical Trial
Molecular Weight

255.22

Formula

C₁₁H₁₃NO₆

CAS No.

1577222-14-0

SMILES

O=C(OCCN1C(CCC1=O)=O)/C=C/C(OC)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (489.77 mM; Need ultrasonic)

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Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.9182 mL 19.5909 mL 39.1819 mL
5 mM 0.7836 mL 3.9182 mL 7.8364 mL
10 mM 0.3918 mL 1.9591 mL 3.9182 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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Keywords:

DiroximelALKS 8700BIIB098ALKS8700ALKS-8700BIIB 098BIIB-098OthersInhibitorinhibitorinhibit

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Product Name:
Diroximel fumarate
Cat. No.:
HY-100375
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