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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
54 Results for "
EGF receptor
" in MedChemExpress (MCE) Product Catalog:
Products (54)
54 Results for "EGF receptor" in MCE Product Catalog:
4
4 Cited Publications
Target:
Research Areas:
AG 1295 is a selective platelet-derived growth factor receptor (PDGFR) tyrosine-kinase inhibitor. AG1295 abolishes autophosphorylation of the PDGFR whereas not affects the autophosphorylation of the EGF receptor .
3
3 Cited Publications
PD168393 is a potent, selective and cell-permeable inhibitor of EGFR tyrosine kinase and ErbB2. PD168393 irreversiblely inactivates EGF receptor ( IC50=0.7 nM) and is inactive against insulin receptor, PDGFR, FGFR and PKC .
3
3 Cited Publications
Cat. No.: HY-P7017
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: HBEGF; Diphtheria Toxin receptor (Heparin-Binding EGF-Like Growth Factor); Prev. HEGFL; Heparin-Binding Epidermal Growth Factor; Prev. DTR; Short Form Heparin-Binding EGF-Like Growth Factor; Prev. DTS; Heparin-Binding EGF-Like Growth Factor; Diphtheria To
Species:
Human
Source:
E. coli
3
3 Cited Publications
Cat. No.: HY-P7194
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: HBEGF; Diphtheria Toxin receptor (Heparin-Binding EGF-Like Growth Factor); Prev. HEGFL; Heparin-Binding Epidermal Growth Factor; Prev. DTR; Short Form Heparin-Binding EGF-Like Growth Factor; Prev. DTS; Heparin-Binding EGF-Like Growth Factor; Diphtheria To
Species:
Mouse
Source:
E. coli
3
3 Cited Publications
Cat. No.: HY-P7400
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: HBEGF; Diphtheria Toxin receptor (Heparin-Binding EGF-Like Growth Factor); Prev. HEGFL; Heparin-Binding Epidermal Growth Factor; Prev. DTR; Short Form Heparin-Binding EGF-Like Growth Factor; Prev. DTS; Heparin-Binding EGF-Like Growth Factor; Diphtheria To
Species:
Human
Source:
CHO
2
2 Cited Publications
Synonyms: EKI-785; WAY-EKI 785
Research Areas:
CL-387785 (EKI-785; WAY-EKI 785) is an orally active EGFR inhibitor with an IC50 of 370 pM. CL-387785 inhibits EGF-stimulated EGFR autophosphorylation with an IC50 of approximately 5 nM. CL-387,785 exerts selective inhibition on cell lines overexpressing EGFR or c-erbB-2, whereas it shows weak inhibitory effects on cell lines with low expression of these two receptors. CL-387785 effectively induces cell cycle arrest and apoptosis. CL-387785 can be used for the research of non-small cell lung cancer and autosomal recessive polycystic kidney disease .
1
1 Cited Publications
Target:
Research Areas:
FT709 is a potent and selective USP9X inhibitor, an IC50 of 82 nM. USP9X has been linked with centrosome function, chromosome alignment during mitosis, EGF receptor degradation, chemo-sensitization, and circadian rhythms .
1
1
1 Cited Publications
Cat. No.: HY-P72487
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: HBEGF; Diphtheria Toxin receptor (Heparin-Binding EGF-Like Growth Factor); Prev. HEGFL; Heparin-Binding Epidermal Growth Factor; Prev. DTR; Short Form Heparin-Binding EGF-Like Growth Factor; Prev. DTS; Heparin-Binding EGF-Like Growth Factor; Diphtheria To
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P80116
Synonyms: Avian erythroblastic leukemia viral (v erb b) oncogene homolog antibody;
Cell growth inhibiting protein 40 antibody;
Cell proliferation inducing protein 61 antibody;
EGF R antibody;
EGFR antibody;
EGFR_HUMAN antibody;
Epidermal growth factor receptor (avian erythroblastic leukemia viral (v erb b) oncogene homolog) antibody;
Epidermal growth factor receptor antibody;
erb-b2 receptor tyrosine kinase 1 antibody;
ERBB antibody;
ERBB1 antibody;
Errp antibody;
HER1 antibody;
mENA antibody;
NISBD2 antibody;
Oncogen ERBB antibody;
PIG61 antibody;
Proto-oncogene c-ErbB-1 antibody;
receptor tyrosine protein kinase ErbB 1 antibody;
receptor tyrosine-protein kinase ErbB-1 antibody;
SA7 antibody;
Species antigen 7 antibody;
Urogastrone antibody;
v-erb-b Avian erythroblastic leukemia viral oncogen homolog antibody;
wa2 antibody;
Wa5 antibody
Cat. No.: HY-P99155
CAS No.: 667901-13-5
Synonyms: 2F8; HUMAX-EGFR
Cat. No.: HY-P10697A
Target:
Research Areas:
Cat. No.: HY-D2004
CAS No.: 1430816-27-5
PD-089828 is an ATP competitive inhibitor of FGFR-1, PDGFR-β and EGFR (IC50s=0.15, 1.76, and 5.47 µM, respectively) and a noncompetitive inhibitor of c-Src tyrosine kinase (IC50=0.18 µM). PD-089828 also inhibits MAPK with an IC50 of 7.1 µM. PD-089828 inhibits PDGF-, EGF- and bFGF-mediated tyrosine kinase receptor autophosphorylation in vitro. PD-089828 has a long-lasting cellular activity .
Cat. No.: HY-P0320
CAS No.: 149261-42-7
Target:
Research Areas:
Cat. No.: HY-P4130
CAS No.: 1180485-56-6
Cat. No.: HY-P2673
CAS No.: 121284-21-7
Synonyms: KRTLRR
Cat. No.: HY-P99155A
CAS No.: 667901-13-5
Cat. No.: HY-129510
CAS No.: 1346601-52-2
4-Methyl erlotinib, is a potent and selective epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor. 4-Methyl erlotinib potently inhibits EGF-mediated tumor cell mitosis by reducing EGFr-specific tyrosine phosphorylation. Using a mouse model of human tumor transplantation, 4-Methyl erlotinib demonstrated significant and sustained suppression of EGFr phosphotyrosine levels, resulting in significant growth inhibition of EGFr-dependent human cancers .
Cat. No.: HY-101756
CAS No.: 150779-71-8
Synonyms: SDZ-LAP 977
SDZ 281-977 is a derivative of the EGF receptor tyrosine kinase inhibitor Lavendustin A.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
