194423-15-9
194423-15-9
Chemical Structure
PD168393
- CAS No.: 194423-15-9
- Formula:C17H13BrN4O
- Molecular Weight:369.22
IUPAC Name: N-(4-((3-bromophenyl)amino)quinazolin-6-yl)acrylamide
InChIKey: HTUBKQUPEREOGA-UHFFFAOYSA-N
SMILES: C=CC(NC1=CC2=C(NC3=CC=CC(Br)=C3)N=CN=C2C=C1)=O
Biological Activity: PD168393 is a potent, selective and cell-permeable inhibitor of EGFR tyrosine kinase and ErbB2. PD168393 irreversiblely inactivates EGF receptor ( IC50=0.7 nM) and is inactive against insulin receptor, PDGFR, FGFR and PKC[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PD168393 | 98.01% | PD168393 is a potent, selective and cell-permeable inhibitor of EGFR tyrosine kinase and ErbB2. PD168393 irreversiblely inactivates EGF receptor ( IC50=0.7 nM) and is inactive against insulin receptor, PDGFR, FGFR and PKC. | ||||||||||||||||||||
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References
Keywords
