1. Protein Tyrosine Kinase/RTK
  2. PDGFR
  3. AG 1295

AG 1295 

Cat. No.: HY-101957
Handling Instructions

AG 1295 is a selective platelet-derived growth factor receptor (PDGFR) tyrosine-kinase inhibitor. AG 1295 reduces neointimal formation in aortic allograft vasculopathy by inhibition of PDGFR-beta-triggered tyrosine phosphorylation.

For research use only. We do not sell to patients.

AG 1295 Chemical Structure

AG 1295 Chemical Structure

CAS No. : 71897-07-9

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Description

AG 1295 is a selective platelet-derived growth factor receptor (PDGFR) tyrosine-kinase inhibitor. AG 1295 reduces neointimal formation in aortic allograft vasculopathy by inhibition of PDGFR-beta-triggered tyrosine phosphorylation[1][2].

IC50 & Target

PDGFR[1]

Molecular Weight

234.30

Formula

C₁₆H₁₄N₂

CAS No.

71897-07-9

SMILES

CC1=C(C)C=C2N=CC(C3=CC=CC=C3)=NC2=C1

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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AG 1295
Cat. No.:
HY-101957
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