PDGF-AA
PDGF-AA is the homodimeric form of platelet-derived growth factor assembled from two A chains, and it signals exclusively through PDGFR-alpha. Produced recombinantly by expressing the PDGF-A chain and allowing disulfide-bonded dimerization, it is a weaker mitogen and chemoattractant than PDGF-BB because it cannot activate PDGFR-beta. Physiologically, PDGF-AA/PDGFR-alpha signaling guides oligodendrocyte precursor cell migration and proliferation in the CNS, supports alveologenesis, and participates in mesenchymal development. In culture it is the reagent of choice for expanding oligodendrocyte progenitors and for dissecting alpha-specific receptor pharmacology. Recombinant PDGF-AA is supplied for proliferation, binding, and PDGFR-alpha inhibitor assays.
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PDGF-AA Recombinant Proteins (3)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formel: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
