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4 Results for "
Erastin (Standard)
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "Erastin (Standard)" in MCE Product Catalog:
Cat. No.: HY-15763R
CAS No.: 571203-78-6
Research Areas:
Erastin (Standard) is the analytical standard of Erastin (HY-15763). This product is intended for research and analytical applications. Erastin is a ferroptosis inducer. Erastin exhibits the mechanism of ferroptosis induction related to ROS and iron-dependent signaling. Erastin inhibits voltage-dependent anion channels (VDAC2/VDAC3) and accelerates oxidation, leading to the accumulation of endogenous reactive oxygen species. Erastin also disrupts mitochondrial permeability transition pore (mPTP) with anti-tumor activity. Furthermore, Erastin can block the uptake of cystine mediated by SLC7A11 and also spares UMRC6-EV and -C91A cells from disulfidptosis under glucose starvation .
Cat. No.: HY-100887R
CAS No.: 1538593-71-3
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Research Areas:
Piperazine Erastin (Standard) is the analytical standard of Piperazine Erastin (HY-100887). This product is intended for research and analytical applications. Piperazine erastin is an analog of erastin which induces an iron-dependent form of non-apoptotic cell death, termed ferroptosis. Piperazine erastin can be used in cancer research .
Cat. No.: HY-114481R
CAS No.: 1801530-11-9
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Research Areas:
Imidazole ketone erastin (Standard) is the analytical standard of Imidazole ketone erastin (HY-114481). This product is intended for research and analytical applications. Imidazole ketone erastin is a potent, selective, and metabolically stable inhibitor of the cystine-glutamate antiporter, system xc - and an activator of ferroptosis. Imidazole ketone erastin has anti-tumor activity .
Cat. No.: HY-100579R
CAS No.: 347174-05-4
Synonyms: Fer-1 (Standard)
Target:
Research Areas:
Ferrostatin-1 (Standard) is the analytical standard of Ferrostatin-1 (HY-100579). This product is intended for research and analytical applications. Ferrostatin-1 (Fer-1), a potent and selective ferroptosis inhibitor, suppresses Erastin-induced ferroptosis in HT-1080 cells (EC50=60 nM). Ferrostatin-1, a synthetic antioxidant, acts via a reductive mechanism to prevent damage to membrane lipids and thereby inhibits cell death. Ferrostatin-1 exhibits antifungal activity .
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Protocols
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