Erastin (Standard)

Erastin (Standard) is the analytical standard of Erastin (HY-15763). This product is intended for research and analytical applications. Erastin is a ferroptosis inducer. Erastin exhibits the mechanism of ferroptosis induction related to ROS and iron-dependent signaling. Erastin inhibits voltage-dependent anion channels (VDAC2/VDAC3) and accelerates oxidation, leading to the accumulation of endogenous reactive oxygen species. Erastin also disrupts mitochondrial permeability transition pore (mPTP) with anti-tumor activity. Furthermore, Erastin can block the uptake of cystine mediated by SLC7A11 and also spares UMRC6-EV and -C91A cells from disulfidptosis under glucose starvation.

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  • CAS No.: 571203-78-6
  • Formule: C30H31ClN4O4
  • Masse moléculaire:547.04
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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100 mg

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