4 Results for "

FAM-DEALA-Hyp-YIPD

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "FAM-DEALA-Hyp-YIPD" in MCE Product Catalog:

Cat. No.: HY-P5908F
Target:  

Inhibitory Antibodies

Research Areas:  

Others

FAM-DEALA-Hyp-YIPD is a fluorescent HIF-1α peptide, with the Kd of 180-560 nM. FAM-DEALA-Hyp-YIPD can be used to assess VHL binding in Fluorescence Polarization (FP) displacement assay, and evaluate the effect of VHL binding on degradation activity .
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Cat. No.: HY-P5915
Research Areas:  

Cancer

FAM-DEALA-Hyp-YIPMDDDFQLRSF-NH2, a 5-FAM labeled HIF-1α peptide, is a substrate of VHL. FAM-DEALA-Hyp-YIPMDDDFQLRSF-NH2 binds to VHL protein with a KD of 3 nM. Ex/Em (λ) = 485/520 nm .
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Cat. No.: HY-122570
CAS No.: 1360616-29-0
Target:  

E1/E2/E3 Enzyme

Research Areas:  

Others

VHL Ligand 38 (Compound 1) is a competitive E3 ubiquitin-protein ligase VHL inhibitor with IC50s of 4.1 and 7.0 μM in 1% and 10% DMSO, respectively. VHL Ligand 38 contains a hydroxyproline residue and an isoxazolylacetamide fragment. VHL Ligand 38 significantly inhibits the binding of a fluorescent peptide derived from HIF1α (FAM-DEALA-Hyp-YIPD) (HY-P5908F) to VHL .
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Cat. No.: HY-P5908
Target:  

Inhibitory Antibodies

Research Areas:  

Cardiovascular Disease

DEALA-Hyp-YIPD is an HIF-1α peptide that inhibits VHL/HIF-1α interaction with an IC50 of 0.91 μM and a Kd of 180 nM .
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