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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
FTY720 analogue
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "FTY720 analogue" in MCE Product Catalog:
Target:
Research Areas:
MP07-66, a FTY720 analogue, is devoid of immunosuppressive effects and shows promising antitumor effects in chronic lymphocytic leukemia by disruption of the SET-PP2A complex leading to PP2A reactivation .
Cat. No.: HY-117720
CAS No.: 1351056-65-9
OSU-2S is a potent PKCδ activator. OSU-2S inhibits cell proliferation and migration. OSU-2S decreases the expression of p-ERK1/2, increases the expression of PKCδ (38 kDa) when combined with Sorafenib (HY-10201). OSU-2S induces Apoptosis. OSU-2S slao is a non-immunosuppressive analogue of FTY720. OSU-2S shows anticancer activity .
Cat. No.: HY-112485
CAS No.: 1142015-25-5
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(R)-FTY720-vinylphosphonate is a sphingosine kinase 1 (SK1) inhibitor. (R)-FTY720-ene-phosphonate is also an FTY720 analogue. (R)-FTY720-vinylphosphonate is promising for research of solid tumors like breast cancer .
Cat. No.: HY-134976
CAS No.: 881914-35-8
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Azido-FTY720 is a photoactivatable analogue of FTY720. Azido-FTY720 is used for identifying binding sites between FTY720 and its receptors . Azido-FTY720 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Cat. No.: HY-12898
CAS No.: 1142015-13-1
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Research Areas:
(S)-FTY-720 Vinylphosphonate is a chiral phosphonate analogue of Fingolimod (HY-11063). (S)-FTY-720 Vinylphosphonate can activate the S1P1 receptor with an EC50 value of 75 nM. (S)-FTY-720 Vinylphosphonate can significantly inhibit Camptothecin (HY-16560)-induced apoptosis in IEC-6 cells. (S)-FTY-720 Vinylphosphonate is applicable for the research of autoimmune diseases .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
