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Flavokavain B

" in MedChemExpress (MCE) Product Catalog:

3

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N2132
    Flavokawain B
    2 Publications Verification

    Flavokavain B

    Apoptosis Caspase PARP Bcl-2 Family NF-κB PI3K Akt p38 MAPK MMP Reactive Oxygen Species (ROS) Cardiovascular Disease Inflammation/Immunology Cancer
    Flavokawain B (Flavokavain B) is an orally active chalcone. Flavokawain B results in activation of caspase-9, -3 and -8, cleavage of PARP. Flavokawain B down-regulates Bcl-2 with concomitant increase in Bax level. Flavokawain B inhibits NF-κB, PI3K/Akt and MAPK signaling pathway. Flavokawain B exhibits Apoptotic effects. Flavokawain B inhibits MMP-9 and promotes ROS generation. Flavokawain B inhibits multiple tumors and inflammation .
    Flavokawain B
  • HY-N2132R

    Flavokavain B (Standard)

    Reference Standards Apoptosis Cancer
    Flavokawain B (Standard) is the analytical standard of Flavokawain B. This product is intended for research and analytical applications. Flavokawain B (Flavokavain B) is a chalcone isolated from the root extracts of kava-kava plant and a potent apoptosis inducer for inhibiting the growth of various cancer cell lines. Flavokawain B (Flavokavain B) shows strong antiangiogenic activity. Flavokawain B (Flavokavain B) inhibits human brain endothelial cell (HUVEC) migration and tube formation with very low and non-toxic concentrations .
    Flavokawain B (Standard)
  • HY-N2132A

    (E/Z)-Flavokavain B

    Drug Derivative Inflammation/Immunology
    (E/Z)-Flavokawain B (compound 4) is a chalcone and nitric oxide production inhibitor with an IC50 of 6.8 μM.(E/Z)-Flavokawain B can be found in the aerial parts of Sarcandra glabra.(E/Z)-Flavokawain B inhibits lipopolysaccharide-induced nitric oxide production .
    (E/Z)-Flavokawain B

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