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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
13 Results for "
Fmoc-PEG6-Val-Cit-PAB-OH
" in MedChemExpress (MCE) Product Catalog:
Products (13)
13 Results for "Fmoc-PEG6-Val-Cit-PAB-OH" in MCE Product Catalog:
Cat. No.: HY-W800623
CAS No.: 2055024-57-0
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Fmoc-PEG6-Val-Cit-PAB-OH is an enzyme-cleavable ADC linker featuring a Boc-protected amine, a hydrophilic PEG spacer, and a Val-Cit-PAB dipeptide. The benzylic alcohol on the PAB can be used to attach with reactive groups such as PNP for conjugation with drug payloads. The Fmoc protecting group may be removed with piperidine to reveal a primary amine which may be used in coupling reactions to form amides. The Val-Cit-PAB is cleaved by cellular proteases for efficient release of payloads to the cell.
Cat. No.: HY-41189
CAS No.: 863971-53-3
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Fmoc-Val-Cit-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Fmoc-Val-Cit-PAB-PNP has superior plasma stability comparable to that of non-cleavable linkers .
Cat. No.: HY-P11295
CAS No.: 3035272-00-2
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Cat. No.: HY-P10563
CAS No.: 2580150-96-3
Synonyms: BHV-1100
Cat. No.: HY-W019682
CAS No.: 84889-09-8
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Cat. No.: HY-P10870
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Cat. No.: HY-P5037
CAS No.: 185213-75-6
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Cat. No.: HY-P5962
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Cat. No.: HY-P5045
CAS No.: 133575-43-6
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Cat. No.: HY-W1050525
CAS No.: 2377585-15-2
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Cat. No.: HY-P5037A
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Cat. No.: HY-P11504
CAS No.: 3109821-26-0
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Cat. No.: HY-P4613
CAS No.: 130674-54-3
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
