673 Results for "

Fungi

" in MedChemExpress (MCE) Product Catalog:
Products (673)

673 Results for "Fungi" in MCE Product Catalog:

174
174 Publications Verification
Cat. No.: HY-A0098
CAS No.: 11089-65-9
Tunicamycin is a mixture of homologous nucleoside antibiotic that inhibits N-linked glycosylation and blocks GlcNAc phosphotransferase (GPT). Tunicamycin causes accumulation of unfolded proteins in cell endoplasmic reticulum (ER) and induces ER stress, and causes blocking of DNA synthesis and cell cycle arrest in G1 phase. Tunicamycin inhibits gram-positive bacteria, yeasts, fungi, and viruses and has anti-cancer activity .Tunicamycin increases exosome release in cervical cancer cells .
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26
26 Cited Publications
Cat. No.: HY-N6687
CAS No.: 52665-69-7
Synonyms: A-23187; Antibiotic A-23187
Calcimycin (A-23187) is an antibiotic and a unique divalent cation ionophore (like calcium and magnesium). Calcimycin induces Ca 2+-dependent cell death by increasing intracellular calcium concentration. Calcimycin inhibits the growth of Gram-positive bacteria and some fungi. Calcimycin also inhibits the activity of ATPase and uncouples oxidative phosphorylation (OXPHOS) of mammalian cells. Calcimycin induces apoptosis and autophagy .
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21
21 Cited Publications
Cat. No.: HY-B0101
CAS No.: 86386-73-4
Synonyms: UK-49858
Fluconazole (UK-49858) is a triazole antifungal agent with excellent activities against a broad range of fungi, especially against Candida albicans. Fluconazole inhibits C. albicans and Candida kefyr with IC99s range from 0.20 μg/mL to 0.39 μg/mL .
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16
16 Cited Publications
Cat. No.: HY-K1002

MCE NP-40 Lysis Buffer is a relatively mild reliable buffers used to lyse cells from animal, plant tissue and fungi, bacteria etc.

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11
11 Cited Publications
Cat. No.: HY-103447
CAS No.: 17924-92-4
Purity:  98.22%
Synonyms: Mycotoxin F2; Toxin F2
Zearalenone is a mycotoxin produced mainly by fungi belonging to the genus Fusarium in foods and feeds. Possess oestrogenic activity in pigs, cattle and sheep, with low acute toxicity. Causes precocious development of mammae and other estrogenic effects in young gilts .
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8
8 Cited Publications
Cat. No.: HY-B0133
CAS No.: 7681-93-8
Synonyms: Pimaricin
Natamycin (Pimaricin) is a macrolide antibiotic agent produced by several Streptomyces strains. Natamycin inhibits the growth of fungi via inhibition of amino acid and glucose transport across the plasma membrane. Natamycin is a food preservative, an antifungal agent in agriculture, and is widely used for fungal keratitis research .
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6
6 Cited Publications
Cat. No.: HY-B1747
CAS No.: 1121-30-8
Research Areas:  

Infection

Pyrithione is an inhibitor of membrane transport processes in fungi. Pyrithione is a potent antibiotic aspergillic acid. Pyrithion incubated Penicillium mycelia would have a marked decrease in the activities of a variety of independently regulated transport systems .
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6
6 Cited Publications
Cat. No.: HY-B0885
CAS No.: 27220-47-9
Synonyms: (±)-Econazol
Econazole ((±)-Econazol) is an orally active imidazole antifungal agent, as well as a cytochrome P-450 inhibitor and a blocker of calcium and manganese ion uptake. Econazole is active against a variety of fungi and some Gram-positive bacteria, but has no significant activity against Gram-negative bacteria. Econazole can inhibit the synthesis of prostaglandins and can also induce liver damage .
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5
5 Cited Publications
Cat. No.: HY-14273
CAS No.: 241479-67-4
Purity:  99.97%
Synonyms: BAL-4815; RO-0094815
Research Areas:  

Infection Cancer

Isavuconazole (BAL-4815) is a triazole proagent with antifungal activity against yeasts, molds, and dimorphic fungi. Isavuconazole inhibits ergosterol biosynthesis and results in the disruption of fungal membrane structure and function. Isavuconazole is a moderate inhibitor of CYP3A4.
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5
5 Cited Publications
Cat. No.: HY-100597
CAS No.: 8047-15-2
Purity:  98.36%
Synonyms: Saponin
Saponins (Saponin) is a class of chemical compound of glycosides found in particular abundance in various plant species. In plants, Saponins may serve as anti-feedants, and to protect the plant against microbes and fungi .
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5
5 Cited Publications
Cat. No.: HY-B1858
CAS No.: 50512-35-1
Isoprothiolane is a blast fungicide with antifungal, anti-inflammatory and insecticidal activities. Isoprothiolane primarily acts on fungi during the penetration and growth stages of infecting hyphae. Isoprothiolane can be used as an insecticide, pesticide, etc. In addition, Isoprothiolane can reduce serum phospholipid and total lipid concentrations, regulating lipid metabolism. Isoprothiolane is also used in the research of fatty liver .
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5
5 Cited Publications
Cat. No.: HY-D0093
CAS No.: 61926-22-5
Synonyms: EthD-1
Ethidium homodimer (EthD-1) is a high-affinity fluorescent nucleic acid dye commonly used to stain mammals, bacteria, yeast, and fungi. Ethidium homodimer binds to DNA or RNA, enhancing fluorescence more than 30 times. The Ethidium homodimer has a strong positive charge, so it cannot cross cell membranes and stain living cells; But the Ethidium homodimer can cross the disordered region of the dead cell membrane to reach the nucleus and embed the DNA double strand to produce red fluorescence. Therefore, Ethidium homodimer is a relatively sensitive nucleic acid stain that can accurately detect nucleic acids in solution or in decomposing cells. Ethidium homodimer binds DNA, Ex/Em=528/617 nm .
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4
4 Cited Publications
Cat. No.: HY-Y0520
CAS No.: 97-65-4
Synonyms: Methylenesuccinic acid
Itaconic acid, a precursor of polymers, chemicals, and fuels, can be synthesized by many fungi. Itaconic acid also is a macrophage-specific metabolite. Itaconic acid mediates crosstalk between macrophage metabolism and peritoneal tumors. Itaconic acid has anti-inflammatory, anti-microbial and immunomodulatory effect .
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4
4 Cited Publications
Cat. No.: HY-N6779
CAS No.: 149-29-1
Synonyms: Terinin
Patulin (Terinin) is a mycotoxin produced by fungi including the Aspergillus, Penicillium, and Byssochlamys species, causes chromosome breakage, mutation, teratogenic and cytotoxic. Patulin induces autophagy-dependent apoptosis through lysosomal-mitochondrial axis, and causes DNA damage .
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3
3 Cited Publications
Cat. No.: HY-N0181
CAS No.: 57-87-4
Ergosterol is the primary sterol found in fungi, with antioxidative, anti-proliferative, and anti-inflammatory effects.
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3
3 Cited Publications
Cat. No.: HY-B1414
CAS No.: 88-04-0
Synonyms: p-Chloro-m-xylenol; PCMX
Chloroxylenol is a broad-spectrum antibacterial agent that can be used to control bacteria, algae, fungi and viruses .
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3
3 Cited Publications
Cat. No.: HY-B0850
CAS No.: 119446-68-3
Research Areas:  

Infection

Difenoconazole is a sterol demethylation inhibitor, as a fungicide. Difenoconazole binds the heme portion of the fungal cytochrome P450 51, interferes the mycelial growth and inhibits the spore germination of pathogens, suppressing fungal growth .
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3
3 Cited Publications
Cat. No.: HY-75958
CAS No.: 511-28-4
Synonyms: 22-Dihydroergocalciferol
Target:  

VD/VDR

Research Areas:  

Metabolic Disease

Vitamin D4 (22-Dihydroergocalciferol) is a Vitamin D derived from fungi. The precursor of Vitamin D4 is 22,23-dihydroergosterol .
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3
3 Cited Publications
Cat. No.: HY-N0216A
CAS No.: 553-54-8
Benzoic acid lithium is an aromatic alcohol found in many plants and is a common additive in food, beverages, cosmetics and other products. Benzoic acid lithium inhibits bacteria and fungi and acts as a preservative .
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3
3 Cited Publications
Cat. No.: HY-N0216
CAS No.: 65-85-0
Benzoic acid is an aromatic alcohol existing naturally in many plants and is a common additive to food, drinks, cosmetics and other products. It acts as preservatives through inhibiting both bacteria and fungi .
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