149-29-1
149-29-1
Chemical Structure
Patulin
Synonym(s): Terinin
- CAS No.: 149-29-1
- Formula:C7H6O4
- Molecular Weight:154.12
IUPAC Name: 4-hydroxy-4H-furo[3,2-c]pyran-2(6H)-one
InChIKey: ZRWPUFFVAOMMNM-UHFFFAOYSA-N
SMILES: O=C1OC2=CCOC(C2=C1)O
Biological Activity: Patulin (Terinin) is a mycotoxin produced by fungi including the Aspergillus, Penicillium, and Byssochlamys species, causes chromosome breakage, mutation, teratogenic and cytotoxic. Patulin induces autophagy-dependent apoptosis through lysosomal-mitochondrial axis, and causes DNA damage[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Patulin | 99.94% | Patulin (Terinin) is a mycotoxin produced by fungi including the Aspergillus, Penicillium, and Byssochlamys species, causes chromosome breakage, mutation, teratogenic and cytotoxic. Patulin induces autophagy-dependent apoptosis through lysosomal-mitochondrial axis, and causes DNA damage. | ||||||||||||||||||||
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Patulin (Standard) | 99.99% | Patulin (Standard) is the analytical standard of Patulin. This product is intended for research and analytical applications. Patulin (Terinin) is a mycotoxin produced by fungi including the Aspergillus, Penicillium, and Byssochlamys species, causes chromosome breakage, mutation, teratogenic and cytotoxic. Patulin induces autophagy-dependent apoptosis through lysosomal-mitochondrial axis, and causes DNA damage. | ||||||||||||||||||||
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Patulin-13C7 | Patulin-13C7 (Terinin-13C7) is the 13C labeled Patulin (HY-N6779). Patulin (Terinin) is a mycotoxin produced by fungi including the Aspergillus, Penicillium, and Byssochlamys species, is suspected to be clastogenic, mutagenic, teratogenic and cytotoxic. Patulin induces autophagy-dependent apoptosis through lysosomal-mitochondrial axis, and causes DNA damage. | |||||||||||||||||||||
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Loliolide | 99.94% | Loliolide (Loliolid) is a β-carotene metabolite. Loliolide reduces caspase 3, 8, 9 expression, enhances PI3K, AKT, SIRT1, inhibits ROS, apoptosis, and blocks NF-κB p65 nuclear translocation. Loliolide protects mitochondria, reduces oxidative stress, and increases cell viability in neuroblastoma cells. Loliolide can be used for the research of UV-induced skin damage and Parkinson’s disease. | ||||||||||||||||||||
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Neopatulin | Neopatulin is a redox isomer and pivotal biogenetic precursor of the potent antibiotic patulin, which is produced by numerous fungal species. Neopatulin can be synthesized through Lewis acid-catalyzed aldol reaction or 2-formyl-1,3-dithiane with 2-(tert-butyldimethylsiloxy)-4-[(tert-butyldimethylsiloxy)-methyl]furan. | |||||||||||||||||||||
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Levoglucosenone | 99.42% | Levoglucosenone Levoglucosenone has unique chemical properties that make it an important intermediate in the production of a wide variety of chemicals, including pharmaceuticals, fragrances and flavorings. Due to its ability to dissolve polar and non-polar compounds, it can also be used as a solvent or fuel additive. | ||||||||||||||||||||
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Citraconic anhydride | 99.81% | Citraconic anhydride (Methylmaleic anhydride) is a derivative of maleic anhydride (HY-Z0060) and novel antigen retrieval solution. Citraconic anhydride reversibly blocks protein amino groups, stabilizing specific enzymes and improving their catalytic performance. Citraconic anhydride reacts with free amino groups on proteins (especially lysine residues), converting positively charged NH3+ into carboxyl groups, thereby disrupting methylene bridge crosslinks caused by Formaldehyde during antigen retrieval. Citraconic anhydride functionalizes Isotactic polypropylene. Citraconic anhydride precisely responds to pH changes to achieve reversible modification. Citraconic anhydride is irritating to skin and eyes. | ||||||||||||||||||||
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Griffonilide | 99.77% | Griffonilide is a steroidal compound that can be isolated from the roots of Semiaquilegia adoxoides. | ||||||||||||||||||||
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(+)-Epiloliolide | 95.0% | (+)-Epiloliolide is a megastigmane that can be isolated from Annona muricata. (+)-epiloliolide increased the nuclear localization of p53. (+)-Epiloliolide has anti-inflammatory effect through upregulating phosphorylation of the PKA/CREB pathway. (+)-Epiloliolide also effectively increases the proliferation and migration of human periodontal ligament cells by downregulating NLRP3 activated by PG-LPS. | ||||||||||||||||||||
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Menisdaurilide | Menisdaurilide is a natural product that can be isolated from Dicentra spectabilis. | |||||||||||||||||||||
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Astepyrone | Astepyrone is a microbial metabolite with a anti-ulcerogenic effect. | |||||||||||||||||||||
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cis-Aconitic anhydride | cis-Aconitic anhydride, in the presence of acetic anhydride, can be used to detect and determine aliphatic tert-amines and alkaloids. Cis-aconitine anhydride reacts with aliphatic tertiary amines in alcoholic solution to form a yellow color. | |||||||||||||||||||||
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References
- [1]. Puel O, et al. Biosynthesis and toxicological effects of patulin. Toxins (Basel). 2010 Apr;2(4):613-31. [Content Brief]
- [2]. Glaser N, et al. Patulin: Mechanism of genotoxicity. Food Chem Toxicol. 2012 May;50(5):1796-801. [Content Brief]
- [3]. Sun M, et al. Patulin Induces Autophagy-Dependent Apoptosis through Lysosomal-Mitochondrial Axis and Impaired Mitophagy in HepG2 Cells. J Agric Food Chem. 2018 Nov 21;66(46):12376-12384. [Content Brief]
- [4]. Glaser N, et al. Patulin: Mechanism of genotoxicity. Food Chem Toxicol. 2012 May;50(5):1796-801. [Content Brief]
